Estudio del efecto de las condiciones de operación en un proceso de ultrafiltración destinado a recuperar compuestos fenólicos contenidos en los extractos líquidos del alperujo

[ES] El alperujo es un residuo semisólido que se obtiene en la elaboración de aceite de oliva virgen, el cual tiene una cantidad de elevada de compuestos fenólicos. Los compuestos fenólicos son productos de alto valor añadido puesto que juegan un importante papel en la nutrición y salud humanas (por ejemplo, en la prevención de determinadas enfermedades como el cáncer). Por ello, las industrias alimentaria, farmacéutica y cosmética han mostrado un creciente interés en este tipo de compuestos. Por otro lado, los compuestos fenólicos, debido a su carácter fitotóxico, suponen un problema a la hora de tratar dichos residuos en las plantas de tratamiento convencionales. Por todo ello, su recuperación es interesante. Este TFM tiene orientación investigadora. Se realizará un trabajo experimental que consiste en la puesta a punto del equipo de ultrafiltración con el que se estudiará la influencia de las condiciones de operación (concentración, velocidad tangencial, presión, tiempo, etc) sobre el rendimiento del proceso en términos de productividad y de recuperación de los polifenoles presentes en los extractos acuosos resultantes de una extracción sólido líquido aplicada al alperujo. A partir de los datos obtenidos, se seleccionarán las condiciones de operación más adecuadas del proceso de ultrafiltración para la recuperación de polifenoles. Este TFM se realizará por parte de la alumna mediante la modalidad de prácticas en empresa en el ISIRYM de la UPV bajo la dirección de las tutoras de este TFM.Casas Roncero, I. (2021). Estudio del efecto de las condiciones de operación en un proceso de ultrafiltración destinado a recuperar compuestos fenólicos contenidos en los extractos líquidos del alperujo. Universitat Politècnica de València. http://hdl.handle.net/10251/171185TFG

A facility and community-based assessment of scabies in rural Malawi.

Background Scabies is a neglected tropical disease of the skin, causing severe itching, stigmatizing skin lesions and systemic complications. Since 2015, the DerMalawi project provide an integrated skin diseases clinics and Tele-dermatology care in Malawi. Clinic based data suggested a progressive increase in scabies cases observed. To better identify and treat individuals with scabies in the region, we shifted from a clinic-based model to a community based outreach programme. Methodology/principal findings From May 2015, DerMalawi project provide integrated skin diseases and Tele-dermatological care in the Nkhotakota and Salima health districts in Malawi. Demographic and clinical data of all patients personally attended are recorded. Due to a progressive increase in the number of cases of scabies the project shifted to a community-based outreach programme. For the community outreach activities, we conducted three visits between 2018 to 2019 and undertook screening in schools and villages of Alinafe Hospital catchment area. Treatment was offered for all the cases and school or household contacts. Scabies increased from 2.9% to 39.2% of all cases seen by the DerMalawi project at clinics between 2015 to 2018. During the community-based activities approximately 50% of the population was assessed in each of three visits. The prevalence of scabies was similar in the first two rounds, 15.4% (2392) at the first visit and 17.2% at the second visit. The prevalence of scabies appeared to be lower (2.4%) at the third visit. The prevalence of impetigo appeared unchanged and was 6.7% at the first visit and 5.2% at the final visit. Conclusions/significance Prevalence of scabies in our setting was very high suggesting that scabies is a major public health problem in parts of Malawi. Further work is required to more accurately assess the burden of disease and develop appropriate public health strategies for its control

ESTUDIO REOLÓGICO DE PINTURAS PLÁSTICAS EN EL PROCESO DE HOMOLOGACIÓN DE UN ADITIVO ESPESANTE, EN UNA EMPRESA DE LA COMUNIDAD VALENCIANA

[ES] El origen del presente Trabajo de Fin de Grado se encuentra en la realización de prácticas en una empresa de fabricación de pinturas situada en la Comunidad Valenciana. Actualmente, la empresa se encuentra con la necesidad de realizar una homologación de un aditivo, utilizado como espesante en gran parte de sus productos, debido al cese de fabricación del mismo por parte del actual proveedor. Ante esta situación, el proveedor ha propuesto a la empresa diversas alternativas y ésta, además, ha buscado otras para aumentar la probabilidad de encontrar un resultado satisfactorio. En total, se van a estudiar 9 espesantes de 5 proveedores distintos como posibles sustitutos del actual. Como se trata de un aditivo reológico, el estudio se va a centrar en analizar la reología de pinturas de diferentes naturalezas fabricadas con cada uno de los posibles sustitutos del espesante. Además, la empresa cuenta con la reciente incorporación de un reómetro, concretamente el modelo MCR 102 de Anton Paar, con el que se van a realizar ensayos rotacionales y oscilatorios que describen el comportamiento de deformación y el flujo de una muestra bajo la acción de una fuerza. En concreto, se estudiarán los siguientes parámetros: la curva de viscosidad, la tixotropía, que permitirá conocer la rapidez con la que la pintura recupera su viscosidad inicial tras someterla a una velocidad de cizalla determinada, y un barrido de amplitud para obtener información sobre la resistencia que presenta la muestra a fluir. Por otro lado, se realizará un ensayo de estabilidad en estufa para asegurar que los sistemas formados con los posibles sustitutos son estables. Los ensayos se realizarán siguiendo la normativa existente para la determinación de parámetros de comportamiento en pinturas y barnices. A partir de los resultados de todos los ensayos, se elegirán aquellos espesantes que se ajusten mejor a las características del actual, los cuales serán propuestos como los más adecuados para el proceso de homologación.[EN] The origin of this Final Degree Project is in the work as an intern in a paint manufacturing company in the Valencian Community. Currently, the company has the necessity to carry out a homologation process of an additive, used in many of its products as a thickener, due to the fact the supplier has recently ended up its manufacturing. In view of this situation, the supplier has proposed several alternatives to the company and this one has also looked for others to increase the probability of finding a satisfactory result. In total, 9 products from 5 different suppliers will be studied as possible substitutes for the current one. As it is a rheological additive, the study will focus on analysing the rheology of paintings of different natures, manufactured with each one of the possible substitutes for the thickener. In addition, the company has recently purchased a rheometer, specifically the MCR 102 model by Anton Paar, which will be used to perform rotational and oscillatory tests that describe the deformation behaviour and flow of a sample under the action of a force. In particular, the following parameters will be studied: the viscosity curve, the thixotropy, which will allow knowing the speed with which the paint recovers its initial viscosity after being submitted to a determined shear rate; and an amplitude sweep, to obtain information on the resistance that the sample shows to flow. On the other hand, a stove stability test will be performed in order to ensure that the systems formed with the possible substitutes are all stable. The tests are carried out following the current standards for the determination of the parameters of behaviour in paints and varnishes. From the results of all the tests, those thickeners that best fit the characteristics of the current one will be chosen and proposed as the most suitable for the homologation process.Casas Roncero, I. (2019). ESTUDIO REOLÓGICO DE PINTURAS PLÁSTICAS EN EL PROCESO DE HOMOLOGACIÓN DE UN ADITIVO ESPESANTE, EN UNA EMPRESA DE LA COMUNIDAD VALENCIANA. http://hdl.handle.net/10251/125643TFG

Patients attended: Scabies, Impetigo and demographic data

A dataset that contains information on patients who received a facility or community-based assessment of Scabies . It contains six variables – age, gender, scabies assessment status, impetigo assessment status, site location, and treatment round number. Data was collected by the DerMalawi project through integrated skin diseases clinics and Tele-dermatology care that they established in 2015 in the Nkhotakota and Salima health districts in Malawi

A facility and community-based assessment of scabies in rural malawi

Altres ajuts: CantabriaLabs; Martiderm; Italfarmaco; Fundación CSAI; Ayuntamiento de Villanueva de la Cañada; Spanish Academy of Dermatology (CG); Colegio Oficial de Médicos de Madrid (CG); Fundación Mutua Madrileña (CG); Celia Delgado Matías Association; Universidad de Salamanca.Background Scabies is a neglected tropical disease of the skin, causing severe itching, stigmatizing skin lesions and systemic complications. Since 2015, the DerMalawi project provide an integrated skin diseases clinics and Tele-dermatology care in Malawi. Clinic based data suggested a progressive increase in scabies cases observed. To better identify and treat individuals with scabies in the region, we shifted from a clinic-based model to a community based outreach programme. Methodology/Principal findings From May 2015, DerMalawi project provide integrated skin diseases and Tele-dermatologi-cal care in the Nkhotakota and Salima health districts in Malawi. Demographic and clinical data of all patients personally attended are recorded. Due to a progressive increase in the number of cases of scabies the project shifted to a community-based outreach programme. For the community outreach activities, we conducted three visits between 2018 to 2019 and undertook screening in schools and villages of Alinafe Hospital catchment area. Treatment was offered for all the cases and school or household contacts. Scabies increased from 2.9% to 39.2% of all cases seen by the DerMalawi project at clinics between 2015 to 2018. During the community-based activities approximately 50% of the population was assessed in each of three visits. The prevalence of scabies was similar in the first two rounds, 15.4% (2392) at the first visit and 17.2% at the second visit. The prevalence of scabies appeared to be lower (2.4%) at the third visit. The prevalence of impetigo appeared unchanged and was 6.7% at the first visit and 5.2% at the final visit. Conclusions/Significance Prevalence of scabies in our setting was very high suggesting that scabies is a major public health problem in parts of Malawi. Further work is required to more accurately assess the burden of disease and develop appropriate public health strategies for its control

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present