4,024 research outputs found
Síndrome hipertensiva hiponatrémica em destaque – um caso clínico
Descrita pela primeira vez em 1952, a síndrome hipertensiva hiponatrémica (SHH) é a combinação de hipertensão severa, hiponatremia e isquémia renal. Mais do que rara, a síndrome é principalmente subdiagnosticada. Isto limita o conhecimento real e completo da sua fisiopatologia e jus_fica a inexistência de estudos aleatorizados prospe_vos com avaliação real de opções terapêu_cas. A necessidade de aumentar a consciencialização para a síndrome por parte da comunidade médica é premente, especialmente se _vermos em consideração que
é uma síndrome potencialmente curável e com taxas de mortalidade que chegam aos 25% nos adultos. Assim, apresenta-se um caso de SHH, com necessidade de nefrectomia para controlo e tratamento definitivo da síndrome.info:eu-repo/semantics/publishedVersio
Development and Validation of an Index Based on EAT-Lancet Recommendations: The Planetary Health Diet Index
The EAT-Lancet Commission has proposed a planetary health diet. We propose the development of the Planetary Health Diet Index (PHDI) based on this proposed reference diet. We used baseline dietary data obtained through a 114-item FFQ from 14, 779 participants of the Longitudinal Study on Adult Health, a multicenter cohort study conducted in Brazil. The PHDI has 16 components and a score from 0 to 150 points. Validation and reliability analyses were performed, including principal component analyses, association with selected nutrients, differences in means between groups (for example, smokers vs. non-smokers), correlations between components and total energy intake, Cronbach''s alpha, item-item correlations, and linear regression analysis between PHDI with carbon footprint and overall dietary quality. The mean PHDI was 60.4 (95% CI 60.2:60.5). The PHDI had six dimensions, was associated in an expected direction with the selected nutrients and was significantly (p < 0.001) lower in smokers (59.0) than in non-smokers (60.6). Cronbach''s alpha value was 0.51. All correlations between components were low, as well as between components and PHDI with total energy intake. After adjustment for age and sex, the PHDI score remained associated (p < 0.001) with a higher overall dietary quality and lower carbon footprint. Thus, we confirmed the PHDI validity and reliability
Hypertriglyceridemic Pancreatitis: Conventional Treatment Versus Therapeutic Plasma Exchange
Introdução:A pancreatite aguda (PA) por hipertrigliceridemia (HTG) pode ser tratada com troca plasmática terapêutica (TPT), com redução rápida dos valores de triglicerídeos. Contudo, não existem estudos comparativos definitivos que comprovem o real benefício desta terapêutica. Objetivo: Comparação dos métodos de tratamento (troca plasmática terapêutica versus convencional) em doentes com PA HTG, durante um período de 12 anos (2000-2012). Métodos: Estudo retrospetivo descritivo e inferencial de 37 doentes, avaliando: sexo, idade, antecedentes pessoais, gravidade, valores de TG e evolução consoante o tratamento (“TPT” ou terapêutica convencional “C”). Resultados: Os dois grupos TPT e C mostraram-se homogéneos quanto ao sexo (p = 0,647), idade (43,5 ± 9,74 anos TPT versus 45,30 ± 9,90 anos C; p = 0.320), pancreatite prévia (40% TPT vs 40,7% C; p = 1,0) alcoolismo crónico (50% TPT vs 70,4% C; p = 0,275) e gravidade pelo score de APACHE II (p = 0,054) e Ranson às 48 horas (p = 0,258). Dos doentes 45,95% apresentava mais de um fator de risco secundário para HTG. O grupo TPT apresentou maiores valores de TG à admissão: 4850 ± 2802 mg/dL vs 1845 ± 1858 mg/dL (p = 0,001). Não se verificaram diferenças na duração do internamento 14,2 ± 6,8 dias vs 13,5 ± 9,0 dias (p = 0,56) ou na taxa de mortalidade (p = 0,47). À data de alta a redução dos TG foi superior no grupo TPT: 4433,70 ± 2896,08 mg/dL - 91,41% vs 1582,95 ± 2051,06 mg/dL – 83,92% (p = 0,002). De referir seis intercorrências minor durante a troca plasmática terapêutica. Discussão/Conclusões: Apesar do viés de seleção (estudo retrospetivo), foi constatada uma maior redução dos TG por esta técnica. As intercorrências inerentes à técnica de troca plasmática terapêutica foram de simples resolução.info:eu-repo/semantics/publishedVersio
Pancreatite Hipertrigliceridémica: Tratamento Convencional Versus Troca Plasmática Terapêutica
Introduction: Acute pancreatitis (AP) induced by hypertriglyceridemia
(HTG) can be treated with therapeutic plasma exchange
(TPE), resulting in rapid reduction of triglyceride level.
However, there are no definitive comparative studies that
prove the real benefits of this therapy.
Objectives: Comparison of treatment methods (TPE versus
conventional) in patients with HTG AP during a period of 12
years (2000-2012).
Methods: Retrospective, descriptive and inferential analysis of
37 patients, evaluating: gender, age, personal pathologic history,
severity of disease, HTG values and evolution depending
on treatment with therapeutic plasma exchange (“TPE”) or
with conventional therapy (“C”).
Results: Both groups TPE and C demonstrated homogeneity
considering gender (p = 0.647), age (43.5 ± 9.74 years TPE vs
45.30 ± 9.90 years C; p = 0.320), prior AP episode (40% TPE
vs 40.7% C; p = 1.0), chronic alcohol consumption (50% TPE
vs 70.4% C; p = 0.275) and severity disease scores: APACHE
II (p = 0.054) and Ranson (p = 0.258). More than one secondary
HTG risk factor was presented in 45.95% of patients
. TPE group presented higher TG levels at admission: 4850
± 2802 mg/dL vs 1845 ± 1858 mg/dL (p = 0.001). No significant
statistical differences were observed considering length
of hospital stay [14.2 ± 6.8 days vs 13.5 ± 9.0 days (p = 0.56)]
or mortality rate (p = 0.47). At discharge, TG reduction was
greater in TPE group: 4433.70 ± 2896.08 mg/dL – 91.41% vs
1582.95 ± 2051.06 mg/dL – 83,92% (p = 0.002). Six minor
complications associated to TPE occurred.
Discussion/Conclusion: Despite the selection bias (retrospective
study), a greater TG reduction was observed with TPE
technique. Complications associated with the technique were
simple to resolveinfo:eu-repo/semantics/publishedVersio
Mobility deficit – Rehabilitate, an opportunity for functionality
There are many pathological conditions that cause mobility deficits and that ultimately influence someone’s autonomy.Aims: to evaluate patients with mobility deficits functional status; to implement a Rehabilitation Nursing intervention plan; to monitor health gains through mobility deficits rehabilitation.Conclusion: Early intervention and the implementation of a nursing rehabilitation intervention plan results in health gains (direct or indirect), decreases the risk of developing Pressure Ulcers (PU) and the risk of developing a situation of immobility that affects patients’ autonomy and quality of life
Associations between health-related quality of life, physical function and fear of falling in older fallers receiving home care
Falls and injuries in older adults have significant consequences and costs, both personal and to society. Although having a high incidence of falls, high prevalence of fear of falling and a lower quality of life, older adults receiving home care are underrepresented in research on older fallers. The objective of this study is to determine the associations between health-related quality of life (HRQOL), fear of falling and physical function in older fallers receiving home care
Адаптация гидравлической модели водостока к бассейнам рек Дунай и Днестр
Гидравлическая модель водостока адаптирована к бассейну рек Дунай и Днестр. По данным орографии, атмосферных осадках или поверхностном стоке она позволяет рассчитывать объемы, расходы и уровни воды с пространственным разрешением 1 км. В модели возможно использование данные об экосистемах на земной поверхности, типах почвы. По данным наблюдений стока оценены среднемесячные величины расходов рек, которые соответствуют наблюдениям, что позволяет применять модель в дальнейших оценках стока, наносов и т.д.Hydraulic model of water inflow is adapted to the Danube and the Dniester rivers basin. According to the orography, precipitation and surface inflow data it permits to calculate water volumes, discharges and levels with spatial resolution 1 km. It is possible to use the data on ecosystems on the ground surface, types of soil in the model. According to the observations data of the inflow the average monthly values of river discharges corresponding to the observations are estimated. It permits to apply the model in the further estimations of inflow, alluvia e t.c
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