6 research outputs found

    Effect of Exercise-Related Factors on the Perception of Time

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    The concept of time whether considered through the lenses of physics or physiology is a relative measure. Alterations in time perception can have serious implications in sport, fitness and work. Accurate perception of time is an important skill with many time constrained sports (i.e., basketball, North American football, tennis, gymnastics, figure skating, ice hockey, and others), and work environments (i.e., workers who need to synchronize their actions such as police and military). In addition, time distortions may play a role in exercise adherence. Individuals may be disinclined to continue with healthy, exercise activities that seem protracted (time dilation). Two predominant theories (scalar expectancy theory and striatal beat frequency model) emphasize the perception of the number of events in a period and the role of neurotransmitters in activating and coordinating cortical structures, respectively. A number of factors including age, sex, body temperature, state of health and fitness, mental concentration and exercise intensity level have been examined for their effect on time perception. However, with the importance of time perception for work, sport and exercise, there is limited research on this area. Since work, sports, and exercise can involve an integration of many of these aforementioned factors, they are interventions that need further investigations. The multiplicity of variables involved with work, sport, and exercise offer an underdeveloped but fruitful field for future research. Thus, the objective of this review was to examine physiological and psychological factors affecting human perception of time and the mechanisms underlying time perception and distortion with activity

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∌99% of the euchromatic genome and is accurate to an error rate of ∌1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Thiopeptide Antibiotics

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    Enantioselective Approach to Quinolizidines: Total Synthesis of Cermizine D and Formal Syntheses of Senepodine G and Cermizine C

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    Terpenoids from Marine Organisms: Unique Structures and their Pharmacological Potential

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