Carolyn Blake

An Alabama native, Carolyn Blake has worked in child nutrition for 37 years.https://egrove.olemiss.edu/icn_ohistories/1167/thumbnail.jp

Adolescents Building Connections (ABC) program evaluation 2022

CERC (formally CERG) has evaluated the Quantum Support Services ABC program that provids tools and strategies to help young people understand the impact of their behaviours and encourage positive growth and maintenance of healthy relationships

Twinning with Tonga : the experiences of Tongan stakeholders with a long-term partnership with regional Victoria, Australia

Twinning programs in health have gained increased recognition as a WHO preferred strategy for providing a sustainable strategy for enhancing the delivery of best practice healthcare globally. The Tonga Twinning Program (TTP), represents a longstanding relationship of some twenty-five years between The Ministry of Health in Tonga and St John of God Hospital, Ballarat, Australia and provides a compelling example of what can be achieved. This article presents the findings from a longitudinal exploration of the experiences and perceptions of the TTP through the voices of those key-stakeholders situated in Tonga who have engaged with the program. Informed by the tenets of hermeneutic phenomenology, a modified thematic analysis highlighted two major themes, ‘A shared mission’ and ‘The outcomes are more than the tangibles’, which supported by a series of sub-themes, identify the core components of the experience of the TTP. This study suggests that the TTP has supported a collective sense of bringing the very best available knowledge and skills to the people of Tonga and has fostered a genuine and open dialogue between partners as a mechanism for change that goes well beyond simply a capacity to replicate skills and instead has establish a genuine reciprocity akin to being a family

Airborne sampling of aerosol particles: Comparison between surface sampling at Christmas Island and P-3 sampling during PEM-Tropics B

Bulk aerosol sampling of soluble ionic compounds from the NASA Wallops Island P-3 aircraft and a tower on Christmas Island during PEM-Tropics B provides an opportunity to assess the magnitude of particle losses in the University of New Hampshire airborne bulk aerosol sampling system. We find that most aerosol-associated ions decrease strongly with height above the sea surface, making direct comparisons between mixing ratios at 30 m on the tower and the lowest flight level of the P-3 (150 m) open to interpretation. Theoretical considerations suggest that vertical gradients of sea-salt aerosol particles should show exponential decreases with height. Observed gradients of Na+ and Mg2+, combining the tower observations with P-3 samples collected below 1 km, are well described by exponential decreases (r values of 0.88 and 0.87, respectively), though the curve fit underestimates average mixing ratios at the surface by 25%. Cascade impactor samples collected on the tower show that \u3e99% of the Na+ and Mg2+mass is on supermicron particles, 65% is in the 1–6 micron range, and just 20% resides on particles with diameters larger than 9 microns. These results indicate that our airborne aerosol sampling probes must be passing particles up to at least 6 microns with high efficiency. We also observed that nss SO42− and NH4+, which are dominantly on accumulation mode particles, tended to decrease between 150 and 1000 m, but they were often considerably higher at the lowest P-3 sampling altitudes than at the tower. This finding is presently not well understood

What drives the involvement of young people in policy making and service improvement? Insights from a map of Scotland’s sexual health system

No abstract available

ExO: An Ontology for Exposure Science

An ontology is a formal representation of knowledge within a domain and typically consists of classes, the properties of those classes, and the relationships between them. Ontologies are critically important for specifying data of interest in a consistent manner, thereby enabling data aggregation, analysis and exchange. An exposure ontology, consistent with those being used in toxicology and other health sciences, is required to formally represent exposure concepts, the relationships between these concepts and most important, the relationships between exposure, susceptibility, and toxicology information. A successful exposure ontology must facilitate the semantic retrieval of exposure data in the context of environmental health science, medical surveillance, disease control, health tracking, risk assessment, and other public health and environmental science endeavors. To address this need, an Exposure Ontology, ExO, was designed and a prototype developed to provide the foundation for exposure data centralization and integration. The root classes forming the basis for the ontology are 'exposure event’ ‘exposure stressor', 'exposure receptor', and 'exposure outcome'. Although the initial development of ExO was focused on human exposure to chemicals, the ultimate intent is to provide domains that can be extended to address exposures to the full suite of environmental stressors

Scorecards and social accountability for improved maternal and newborn health services: a pilot in the Ashanti and Volta regions of Ghana

Background: With the limited availability of quality emergency obstetric and newborn care (EmONC) in Ghana, and a lack of dialogue on the issue at district level, the Evidence for Action (E4A) program (2011-2015) initiated a pilot intervention using a social accountability approach in two regions of Ghana. Objective: Using scorecards to assess and improve maternal and newborn health services, the intervention study evaluated the effectiveness of engaging multiple, health and non-health sector stakeholders at district level to improve the enabling environment for quality EmONC. Methods: The quantitative study component comprised two rounds of assessments in 37 health facilities. The qualitative component is based on an independent prospective policy study. Results: Results show a marked growth in a culture of accountability, with heightened levels of community participation, transparency, and improved clarity of lines of accountability among decision-makers. The breadth and type of quality of care improvements were dependent on the strength of community and government engagement in the process, especially in regard to more complex systemic changes. Conclusion: Engaging a broad network of stakeholders to support MNH services has great potential if implemented in ways that are context-appropriate and that build around full collaboration with government and civil society stakeholders

Visualizing Mechanics: Improving Student Learning through Video Demonstrations

The Purdue Mechanics Freeform Classroom (PMFC) is a project that seeks to reform engineering mechanics education by integrating content and technology; enhancing communication between students, their peers, and instructors; accommodating a broader range of learning styles; and facilitating greater depths of understanding. In an attempt to increase the PMFC’s efficacy, a series of demonstration videos has been produced. As demonstrated by the popularity and pervasiveness of websites such as YouTube, short videos have the potential to captivate audiences. As such, these videos have incredible promise in educational contexts. In the PMFC series of videos, entitled Visualizing Mechanics, each imitates the length and format of a generic YouTube video, but is specifically designed to highlight and elucidate interesting phenomena in engineering mechanics. Various techniques are used in the course of video production, including student voiceovers, equation overlays, and advanced video enhancement techniques designed to improve student visualization. The result is videos capable of conveying key mechanics concepts that could not easily be recreated in a classroom setting. To date, the videos have been produced for only one class, ME 274: Basic Mechanics II at Purdue University, which provides an overview of particle and rigid body kinematics and kinetics, as well as an introduction to mechanical vibrations. Once this initial batch of videos is finalized, student surveys and YouTube Analytics tools will be used to assess their effectiveness. If the results of this assessment prove positive, the approach will be expanded to incorporate additional course content and allow for distribution to other colleges and universities outside the Purdue University College of Engineering

Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays

BACKGROUND: DNA microarrays are rapidly becoming a fundamental tool in discovery-based genomic and biomedical research. However, the reliability of the microarray results is being challenged due to the existence of different technologies and non-standard methods of data analysis and interpretation. In the absence of a "gold standard"/"reference method" for the gene expression measurements, studies evaluating and comparing the performance of various microarray platforms have often yielded subjective and conflicting conclusions. To address this issue we have conducted a large scale TaqMan(® )Gene Expression Assay based real-time PCR experiment and used this data set as the reference to evaluate the performance of two representative commercial microarray platforms. RESULTS: In this study, we analyzed the gene expression profiles of three human tissues: brain, lung, liver and one universal human reference sample (UHR) using two representative commercial long-oligonucleotide microarray platforms: (1) Applied Biosystems Human Genome Survey Microarrays (based on single-color detection); (2) Agilent Whole Human Genome Oligo Microarrays (based on two-color detection). 1,375 genes represented by both microarray platforms and spanning a wide dynamic range in gene expression levels, were selected for TaqMan(® )Gene Expression Assay based real-time PCR validation. For each platform, four technical replicates were performed on the same total RNA samples according to each manufacturer's standard protocols. For Agilent arrays, comparative hybridization was performed using incorporation of Cy5 for brain/lung/liver RNA and Cy3 for UHR RNA (common reference). Using the TaqMan(® )Gene Expression Assay based real-time PCR data set as the reference set, the performance of the two microarray platforms was evaluated focusing on the following criteria: (1) Sensitivity and accuracy in detection of expression; (2) Fold change correlation with real-time PCR data in pair-wise tissues as well as in gene expression profiles determined across all tissues; (3) Sensitivity and accuracy in detection of differential expression. CONCLUSION: Our study provides one of the largest "reference" data set of gene expression measurements using TaqMan(® )Gene Expression Assay based real-time PCR technology. This data set allowed us to use an alternative gene expression technology to evaluate the performance of different microarray platforms. We conclude that microarrays are indeed invaluable discovery tools with acceptable reliability for genome-wide gene expression screening, though validation of putative changes in gene expression remains advisable. Our study also characterizes the limitations of microarrays; understanding these limitations will enable researchers to more effectively evaluate microarray results in a more cautious and appropriate manner