Sample description for genotyped samples.

a<p>Discordant: Phenotype deficient, but with wild type for the Med- allele. The three discordant females were all homozygous WT against the Med allele assay.</p

Unadjusted ORs and AORs for phenotypic G6PD deficiency stratified by sex.

a<p>Odds ratios adjusted for village (unpublished data); age group and tribe were dropped due to no univariate effect (age group) or low sample sizes (tribe).</p

Characteristics of cases and controls.

a<p>Data missing from four controls.</p>b<p>Chi² = 59.5, <i>p</i><0.001.</p

The geographical distribution of studies and patients by country.

<p>The geographical distribution of studies and patients by country.</p

Box plot showing duration of follow-up in VL studies.

<p>The majority of studies (104 studies, 21,070 patients) had a follow-up duration of six months. Two studies (406 patients) had a nine month follow-up duration and 24 studies (4,546 patients) had a one year follow-up duration.</p

The geographical distribution of studies and patients by country.

<p>The geographical distribution of studies and patients by country.</p

Pie chart and table showing the design and method of patient allocation in published visceral leishmaniasis clinical studies.

<p>Pie chart and table showing the design and method of patient allocation in published visceral leishmaniasis clinical studies.</p

The drugs and dose regimens used in visceral leishmaniasis clinical studies.

<p>The drugs and dose regimens used in visceral leishmaniasis clinical studies.</p

The number of visceral leishmaniasis clinical trials identified in searches of clinical trial registries and publication databases.

<p>The number of visceral leishmaniasis clinical trials identified in searches of clinical trial registries and publication databases.</p

Bar chart showing dose regimens used in visceral leishmaniasis clinical studies.

<p>Bars show the number of patients treated with the drug in visceral leishmaniasis clinical studies. Bars are colored according to the dose regimen.</p