Minima moralia y la parataxis filosófica: la dialéctica del fragmento de Theodor Adorno

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A modified Brazilian test for the generalized-fracturetoughness determination in multimaterial corners. Numerical and experimental results

IX CONGRESO NACIONAL DE MATERIALES COMPUESTOS. Celebrado en Girona, 5, 6, 7 y 8 de julio de 2011In the present work, a general procedure for the experimental evaluation of the generalized fracture toughness in multimaterial corners is defined. The proposed method is suitable for closed corners (all material wedges being bonded) having two singular terms in the asymptotic stress representation at the corner tip. For a particular corner configuration, the method finds the load configuration at which one of the singular terms vanishes, thus the main stress contribution being controlled by the other non-vanishing singular term. The experimental test, until failure, using the previously defined load configuration allows the generalized fracture toughness associated to each singular term to be evaluated. The whole procedure has been applied to a bimaterial CFRP-Adhesive bimaterial corner and the generalized fracture toughness values have been obtained. The testing of mixed modes has permitted a failure envelope based on the generalized fracture toughness values at the corner tip to be defined. Previously published results, with different geometries, but involving the same corner, have shown that the failure envelope can predict accurately the failure initiation at these corners.Junta de Andalucía y Fondo Social Europeo P08-TEP-4071Junta de Andalucía y Fondo Social Europeo P08-TEP-4051Ministerio de Ciencia e Innovación MAT2009-14022CAPES Ministerio de Educación de Brasi

Are there stable long-range ordered Fe(1-x)Cr(x) compounds?

The heat of formation of Fe-Cr alloys undergoes an anomalous change of sign at small Cr concentrations. This observation raises the question whether there are intermetallic phases present in this composition range. Here we report the discovery of several long-range ordered structures that represent ground state phases at zero Kelvin. In particular we have identified a structure at 3.7% Cr with an embedding energy which is 49 meV/Cr atom below the solid solution. This implies there is an effective long-range attractive interaction between Cr atoms. We propose that the structures found in this study complete the low temperature-low Cr region of the phase diagram.Comment: 3 pages, 2 figure

Scalable Parallel Numerical CSP Solver

We present a parallel solver for numerical constraint satisfaction problems (NCSPs) that can scale on a number of cores. Our proposed method runs worker solvers on the available cores and simultaneously the workers cooperate for the search space distribution and balancing. In the experiments, we attained up to 119-fold speedup using 256 cores of a parallel computer.Comment: The final publication is available at Springe

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action

Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to provide disease control. Numerous biological therapies are in various stages of clinical development, with expectation of providing enhanced safety and efficacy over currently available psoriasis therapies. Efalizumab, a recombinant humanized monoclonal IgG1 antibody, is a novel targeted T-cell modulator that inhibits multiple steps in the immune cascade that result in the production and maintenance of psoriatic plaques, including initial T-cell activation and T-cell trafficking into sites of inflammation, including psoriatic skin, with subsequent reactivation in these sites. This article reviews the pharmacodynamic, pharmacokinetic and clinical effects observed during phase I, II and III efalizumab trials in patients with moderate to severe chronic plaque psoriasis. Copyright (C) 2004 S. Karger AG, Basel

Towards durable multistakeholder-generated solutions: The pilot application of a problem-oriented policy learning protocol to legality verification and community rights in Peru

This paper reports and reflects on the pilot application of an 11-step policy learning protocol that was developed by Cashore and Lupberger (2015) based on several years of Cashore’s multi-author collaborations. The protocol was applied for the first time in Peru in 2015 and 2016 by the IUFRO Working Party on Forest Policy Learning Architectures (hereinafter referred to as the project team). The protocol integrates insights from policy learning scholarship (Hall 1993, Sabatier 1999) with Bernstein and Cashore’s (2000, 2012) four pathways of influence framework. The pilot implementation in Peru focused on how global timber legality verification interventions might be harnessed to promote local land rights. Legality verification focuses attention on the checking and auditing of forest management units in order to verify that timber is harvested and traded in compliance with the law. We specifically asked: How can community legal ownership of, and access to, forestland and forest resources be enhanced? The protocol was designed as a dynamic tool, the implementation of which fosters iterative rather than linear processes. It directly integrated two objectives: 1) identifying the causal processes through which global governance initiatives might be harnessed to produce durable results ‘on the ground’; 2) generating insights and strategies in collaboration with relevant stakeholders. This paper reviews and critically evaluates our work in designing and piloting the protocol. We assess what seemed to work well and suggest modifications, including an original diagnostic framework for nurturing durable change. We also assess the implications of the pilot application of the protocol for policy implementation that works to enhance the influence of existing international policy instruments, rather than contributing to fragmentation and incoherence by creating new ones