8 research outputs found

    Dataset OROV

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    <p><b>First outbreak of Oropouche Fever reported in a non-endemic central-western region of the Peruvian Amazon. </b><b>Molecular diagnosis and clinical characteristics. </b></p><p><b>Introduction: </b>Oropouche virus (OROV) is an underreported and emerging infectious disease. Its incidence is underestimated mainly due to clinical similarities with other diseases that are also caused by arboviruses present in endemic areas. We report the first outbreak of OROV in the western region of the Peruvian Amazon in the department of Huanuco, Peru. </p><p><b>Methods</b>: This outbreak occurred in the region of Huanuco, Peru during July of 2016. Blood samples were taken from 268 patients who presented acute febrile syndrome to be later analyzed for Oropouche Virus via Polymerase Chain Reaction.</p><p><b>Results</b>: Of all 268 patients, 46 (17%) cases tested were positive for OROV. the most common symptom reported was headaches with a frequency of 87% (n=40) followed by myalgias with 76% (n=35), arthralgias with 65.2% (n=30), retro-ocular pain 60.8% (n=28) and hyporexia with 50% (n=23). </p><p> Concerning signs and symptoms that may suggest severe OROV infection, 4.3% (n=2) had low platelet count, 8.6% (n=4) had intense abdominal pain, and only 2.1% (n=1) had a presentation with thoracic pain<br></p

    Dataset HPV 2018

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    <p><b>Frequency and coinfection between genotypes of Human papillomavirus in a population of asymptomatic women in northern Peru.</b></p><p><b><br></b></p><p></p><p><b>Objective:</b> Describe the prevalence of HPV genotypes via PCR and DNA sequencing in 397 women who attended to the gynecological outpatient clinic in the Hospital Regional Docente de Cajamarca from March to September 2017.</p> <p><b>Results:</b> A positive PCR result for HPV was observed in 121 cervical samples. A high-risk genotype was found in 63.6% (77/121) of patients, a probably oncogenic type in 23.1% (28/121) and a low-risk type in 7.4%. Among the high-risk genotypes, HPV-31 was the most common one present in 20% (21/77), followed by HPV-16 in 11.4% (12/77). Coinfections between two or more genotypes were observed in 12 cases.</p><b></b><p></p
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