54 research outputs found
Access to administrative documents and to public sector information in Italy
Law No. 241 of 1990 on administrative procedure (Italian APA) established general rules on the right of access to administrative documents for the first time in the Italian legal system, which partly reproduced rules defined in sectorial legislations. From such very restrictive regime of access to administrative documents\u2014lately accompanied by a rather demagogical obligation imposed on public administrations to disclose a set of information in the context of the so-called open data policies\u2014Italy has recently moved forth to public access to data and documents held by public administrations
Transvaginal strain elastosonography in the differential diagnosis of rectal endometriosis: Some potentials and limits
We sincerely thank SzabĂł et al [...]
How and why do species break a developmental trade-off? Elucidating the association of trichomes and stomata across species.
PREMISE
Previous studies have suggested a trade-off between trichome density (Dt) and stomatal density (Ds) due to shared cell precursors. We clarified how, when, and why this developmental trade-off may be overcome across species.
METHODS
We derived equations to determine the developmental basis for Dt and Ds in trichome and stomatal indices (it and is) and the sizes of epidermal pavement cells (e), trichome bases (t), and stomata (s) and quantified the importance of these determinants of Dt and Ds for 78 California species. We compiled 17 previous studies of Dt-Ds relationships to determine the commonness of Dt-Ds associations. We modeled the consequences of different Dt-Ds associations for plant carbon balance.
RESULTS
Our analyses showed that higher Dt was determined by higher it and lower e, and higher Ds by higher is and lower e. Across California species, positive Dt-Ds coordination arose due to it-is coordination and impacts of the variation in e. A Dt-Ds trade-off was found in only 30% of studies. Heuristic modeling showed that species sets would have the highest carbon balance with a positive or negative relationship or decoupling of Dt and Ds, depending on environmental conditions.
CONCLUSIONS
Shared precursor cells of trichomes and stomata do not limit higher numbers of both cell types or drive a general Dt-Ds trade-off across species. This developmental flexibility across diverse species enables different Dt-Ds associations according to environmental pressures. Developmental trait analysis can clarify how contrasting trait associations would arise within and across species
The limits and potentials of presepsin in orthopaedic surgery: state of the art and future directions
Presepsin, i.e. the soluble cluster of differentiation 14-SubType (sCD14-ST), is an emerging biomarker
for the diagnosis and evaluation of sepsis and infection. In 2004, Yaegashi et al. originally described
presepsin as a potential biomarker; since then, several studies have investigated the role of presepsin in
different infectious conditions, including neonatal sepsis, severe acute pancreatitis, infections in patients
with haematological malignancies, severe community-acquired pneumonia, pacemaker and implantable
cardioverter-defibrillator (ICD) pocket infections, surgical site infections (SSIs) and periprosthetic joint
infects (PJIs). Moreover, presepsin has been also studied in the risk stratification in cardiac surgery patients,
and as a biomarker in the perioperative management of patients undergoing total hip arthroplasty (THA)
or total knee arthroplasty (TKA). This review aims to summarize the current knowledge about presepsin,
focusing on the limits and potentials that the use of this biomarker could have in daily clinical practice.
Presepsin is could be useful in daily clinical practice in orthopaedic surgery in the diagnosis and prevention
of SSIs and PJIs. It is a cost-effective biomarker, but to improve its accuracy, it is important to carefully
recalculate presepsin circulating values in patients with chronic kidney disease. However, further studies
with larger patients’ samples are needed to better validate the use of this biomarker in orthopaedics. In the
future, synovial fluid presepsin might be a useful biomarker in the diagnosis of septic arthritis and PJIs
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