Prospects for an orbital determination and capture cell experiment

A dust experiment which combines measurements of the elemental and isotopic composition of individual particles with orbital information would contribute fundamental, new scientific information on the sources contributing to the micrometeoroid population. The general boundary conditions for such a system are: (1) it must be capable of measuring velocities in the range of 10 km/sec to 100 km/sec with several percent accuracy; (2) it must collect particles in such a way that the debris atoms are locally concentrated so that precise isotopic measurements are possible; (3) it should collect particles over a wide range of sizes starting with a lower limit of 10 microns; (4) it should incorporate materials that will not compromise the isotopic measurements; and (5) it should be large enough to obtain statistically meaningful results within a reasonable exposure time. Techniques which may satisfy these conditions are described

Hartford Hub: Transforming Lower Lincoln

Breeah S. Carey received her degree in speech, language, and hearing sciences with minors in Spanish and psychology from Purdue University in May 2018. She is currently pursuing her master’s degree in speech-language pathology at Purdue University and wants to serve pediatric clients in school and clinic settings. She has volunteered in various schools in Newark, New Jersey, as a tutor in her mother’s after-school program and as a speaker for the Diamond’s in the Rough Program at Belmont Runyon Elementary School, where she encouraged minority girls to attend college in the future. Lauren Jankowski is a senior in interdisciplinary engineering who plans to pursue graduate school and focus her research on mental illness. She has volunteered with several organizations, such as St. Vincent de Paul, Hannah’s House, and Upward Basketball, since early high school. Madison Long received her degree in accounting from Purdue University in 2017 and began her career with Microsoft Corporation in Seattle, Washington, in their finance division. At Purdue, she frequently participated in local Lafayette community initiatives centered around child literacy and engagement, including United Way’s Read to Succeed Program and the Beck Lane Boys and Girls Club after-school volunteering program. Joshua Walker is a senior in mechanical engineering with a minor in computer science and plans to earn a master’s degree in mechanical engineering after a few years of work experience. He has provided one-on-one assistance with students at the free Math and Science Tutoring Center in his high school, refurbished bicycles intended for community use at Revolutions Bicycle Cooperative in Memphis, Tennessee, and worked with Engineers for a Sustainable World to keep tailgating parties at Purdue clean of trash

Invasive Ruins

The purpose of this thesis is to search for a way in which architecture can become a tool used to create a new definition for age-value and historic-value. Instead of proposing an architecture typology that will exist and be admired \u27forever\u27, the proposal becomes a suggestion of ruin; to allow the new building language to age over time alongside with its natural site

Postprandial morphological response of the intestinal epithelium of the Burmese python (Python molurus)

The postprandial morphological changes of the intestinal epithelium of Burmese pythons were examined using fasting pythons and at eight time points after feeding. In fasting pythons, tightly packed enterocytes possess very short microvilli and are arranged in a pseudostratified fashion. Enterocyte width increases by 23% within 24 h postfeeding, inducing significant increases in villus length and intestinal mass. By 6 days postfeeding, enterocyte volume had peaked, following as much as an 80% increase. Contributing to enterocyte hypertrophy is the cellular accumulation of lipid droplets at the tips and edges of the villi of the proximal and middle small intestine, but which were absent in the distal small intestine. At 3 days postfeeding, conventional and environmental scanning electron microscopy revealed cracks and lipid extrusion along the narrow edges of the villi and at the villus tips. Transmission electron microscopy demonstrated the rapid postprandial lengthening of enterocyte microvilli, increasing 4.8-fold in length within 24 h, and the maintaining of that length through digestion. Beginning at 24 h postfeeding, spherical particles were found embedded apically within enterocytes of the proximal and middle small intestine. These particles possessed an annular-like construction and were stained with the calcium-stain Alizarine red S suggesting that they were bone in origin. Following the completion of digestion, many of the postprandial responses were reversed, as observed by the atrophy of enterocytes, the shortening of villi, and the retraction of the microvilli. Further exploration of the python intestine will reveal the underlying mechanisms of these trophic responses and the origin and fate of the engulfed particles

Out of sight but not out of harm’s way: human disturbance reduces reproductive success of a cavity-nesting seabird

While negative effects of human disturbance on animals living above the ground have been widely reported, few studies have considered effects on animals occupying cavities or burrows underground. It is generally assumed that, in the absence of direct visual contact, such species are less vulnerable to disturbance. Seabird colonies can support large populations of burrow- and cavity-nesting species and attract increasing numbers of tourists. We investigated the potential effects of recreational disturbance on the reproductive behaviour of the European storm petrel <i>Hydrobates pelagicus</i>, a nocturnally-active cavity-nesting seabird. Reproductive phenology and outcome of nests subject to high and low levels of visitor pressure were recorded in two consecutive years. Hatching success did not differ between disturbance levels, but overall nestling mortality was significantly higher in areas exposed to high visitor pressure. Although visitor numbers were consistent throughout the season, the magnitude and rate of a seasonal decline in productivity were significantly greater in nests subject to high disturbance. This study presents good evidence that, even when humans do not pose a direct mortality risk, animals may perceive them as a predation risk. This has implications for the conservation and management of a diverse range of burrow- and cavity-dwelling animals. Despite this reduction in individual fitness, overall colony productivity was reduced by ≤1.6% compared with that expected in the absence of visitors. While the colony-level consequences at the site in question may be considered minor, conservation managers must evaluate the trade-off between potential costs and benefits of public access on a site- and species-specific basis

Craniofacial dysmorphology in 22q11.2 deletion syndrome by 3D laser surface imaging and geometric morphometrics: illuminating the developmental relationship to risk for psychosis

Persons with 22q11.2 deletion syndrome (22q11.2DS) are characterized inter alia by facial dysmorphology and greatly increased risk for psychotic illness. Recent studies indicate facial dysmorphology in adults with schizophrenia. This study evaluates the extent to which the facial dysmorphology of 22q11.2DS is similar to or different from that evident in schizophrenia. Twenty-one 22q11.2DS-sibling control pairs were assessed using 3D laser surface imaging. Geometric morphometrics was applied to 30 anatomical landmarks, 480 geometrically homologous semi-landmarks on curves and 1720 semi-landmarks interpolated on each 3D facial surface. Principal component (PC) analysis of overall shape space indicated PC2 to strongly distinguish 22q11.2DS from controls. Visualization of PC2 indicated 22q11.2DS and schizophrenia to be similar in terms of overall widening of the upper face, lateral displacement of the eyes/orbits, prominence of the cheeks, narrowing of the lower face, narrowing of nasal prominences and posterior displacement of the chin; they differed in terms of facial length (increased in 22q11.2DS, decreased in schizophrenia), mid-face and nasal prominences (displaced upwards and outwards in 22q11.2DS, less prominent in schizophrenia); lips (more prominent in 22q11.2DS; less prominent in schizophrenia) and mouth (open mouth posture in 22q11.2DS; closed mouth posture in schizophrenia). These findings directly implicate dysmorphogenesis in a cerebral-craniofacial domain that is common to 22q11.2DS and schizophrenia and which may repay further clinical and genetic interrogation in relation to the developmental origins of psychotic illness

Predicting outcome in acute low back pain using different models of patient profiling

This is a non-final version of an article published in final form in Spine, 34(18), 1970 - 1975, 2009. Copyright © 2009 Lippincott Williams & Wilkins, Inc.Study Design. Prospective observational study of prognostic indicators, using data from a randomized, controlled trial of physiotherapy care of acute low back pain (ALBP) with follow-up at 6 weeks, 3 months, and 6 months. Objective. To evaluate which patient profile offers the most useful guide to long-term outcome in ALBP. Summary of Background Data. The evidence used to inform prognostic decision-making is derived largely from studies where baseline data are used to predict future status. Clinicians often see patients on multiple occasions so may profile patients in a variety of ways. It is worth considering if better prognostic decisions can be made from alternative profiles. Methods. Clinical, psychological, and demographic data were collected from a sample of 54 ALBP patients. Three clinical profiles were developed from information collected at baseline, information collected at 6 weeks, and the change in status between these 2 time points. A series of regression models were used to determine the independent and relative contributions of these profiles to the prediction of chronic pain and disability. Results. The baseline profile predicted long-term pain only. The 6-week profile predicted both long-term pain and disability. The change profile only predicted long-term disability (P 0.05). A similar result was obtained when the order of entry was reversed. When predicting long-term disability, after the 6-week profile was entered at the first step, the change profile was not significant when forced in at the second step. However, when the change profile was entered at the first step and the 6-week clinical profile was forced in at the second step, a significant contribution of the 6-week profile was found. Conclusion. The profile derived from information collected at 6 weeks provided the best guide to long-term pain and disability. The baseline profile and change in status offered less predictive value