41 research outputs found
SPATIAL EFFECTS: 3D MOVEMENT OF A VIRTUAL SOUND SOURCE
This document intends to explain the audio development project proposed to emulate the spatial effect of having a sound source moving in a 3D sonic environment. Throughout this document the reader will see a detailed explanation of how the problem was approached, the specific requirements needed to achieve the result, how this requirements were implemented using MatLab coding and how the end product was tested to evaluate the effectiveness of the solution provided. MatLab files will also be provided so that the reader can associate the concepts being described in order to have a better understanding of the process followed to develop this application.Architecture & Allied Art
Health as a Symbolic Media Interchanging between Body and Social System
Genetics of disease, diagnosis and treatmen
[The impact of bisphosphonates on orthodontic treatment].
Item does not contain fulltextBisphosphonates are used in the treatment of various diseases which are associated with a disturbance of the balance between bone apposition and degradation. The most important complication of bisphosphonate use is osteonecrosis of the jaw. Certain components of an orthodontic treatment plan, such as the extraction of 1 or more teeth, are important risk factors in developing this complication. In addition to the desired effects on the bone metabolism, bisphosphonates may delay tooth eruption and inhibit or block orthodontic tooth movement. Nevertheless, case studies suggest that orthodontic treatment is possible despite the use of bisphosphonates. However, it is recommended to avoid orthodontic treatment unless this is strictly indicated.1 april 201
Prenatal diagnosis of craniomaxillofacial malformations: a characterization of phenotypes in trisomies 13, 18, and 21 by ultrasound and pathology.
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89665.pdf (publisher's version ) (Open Access)OBJECTIVE: To determine the relationship between trisomies 13, 18, and 21 and craniofacial malformations detected by prenatal sonography. DESIGN: During a 29-year period (1976 through 2004), prenatal sonographic findings of 69 fetuses with trisomy 13; 171 fetuses with trisomy 18; 302 fetuses with trisomy 21; and 17 fetuses with other trisomies were evaluated retrospectively, after fetal karyotype identification. Sonographic findings were compared with autopsy results in 209 patients (trisomy 13, n=39; trisomy 18, n=64; and trisomy 21, n=106). RESULTS: For trisomy 13, cleft deformities were detected prenatally in 65.2%, and of the 39 cases with pathological information, 76.9% were found to have a cleft deformity. Ocular and orbital abnormalities were found in 28%. Malformations of the jaws and abnormal profiles were more frequently diagnosed postnatally than prenatally. For trisomy 18, abnormal profiles (41.5%) and ear abnormalities (5.3%) were the most noticeable ultrasound markers, next to abnormalities of the neurocranium (36.8%) and cranial bone configuration (21.6%). Dysmorphisms of the eye, ear, or nose were detected more frequently in autopsy cases. For trisomy 21, ultrasound showed an aberrant shape of the skull in 14.2% of fetuses. In general, the ocular-orbital and nasal abnormalities in fetuses with trisomy 18 or 21 were more evident in pathological examination than in prenatal ultrasound imaging. CONCLUSIONS: Facial anomalies are common in the major trisomies, and their prenatal sonographic identification should be improved. The above-mentioned facial anomalies provide sufficient reason to consider performing cytogenic evaluation.1 maart 201
[Genetics and tooth eruption disorders: a future exploration].
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DESA1002 'Continuous City' Henry Szmelcer
My project is an architectural college situated in Venice. My idea was inspired by the cities connection with historical and evolving architecture. I expressed this tradition through my own project by taking advantage of the cities surrounding architectural masterpieces, where better to study architecture? The college is extremely selective consisting of a single class, single studio room where students will partake in most of their private and tutored studies. A computer room which provides printing and scanning capabilities, a single lecture room, interior cafe, 3 courtyards, and an exhibition room which displays the work of students. The college is located between 3 main roads, I took advantage of this by directly linking the main roads to the college where you can enter though 2 main entrances and a single side entrance. I integrated the site to highlight these entrances. The entrances to the building are very inviting; I used the geometric shape and large doors to highlight this. The two main entrances also have courtyards with landscaping before you enter, after you enter through the larger courtyard there’s a double heighted ceiling allowing you to see the roof of the first floor level from the ground floor lobby. The appearance of my project intends to bring together the historic and modern architecture of Venice, I achieved this by creating a modern form which I’ve designed to appear as if it’s growing out of the site itself, and I’ve used the material of the surrounding buildings as clad, these materials are Stone, concrete, copper. The interior of my project was designed to be an open space whilst maintaining the separation of spaces. To achieve this I used glass partitions inside the building, an elevator and spiral staircase at the centre of the building, a double heighted ceiling and an interior balcony, a geometric layout of areas to provide a flow throughout the building and a connection between all 3 levels
Orthodontic and orthognathic management of a patient with Apert syndrome: a case report.
Item does not contain fulltextThis case report describes the combined orthodontic and orthognathic management of a 14-year-old girl affected with Apert syndrome. She presented with a severe Class III skeletal relationship, midfacial hypoplasia and an large anterior open bite. Intraorally, she had severe crowding, a narrow maxilla and lateral posterior crossbites. The patient was treated with a combination of removable and fixed appliances, a transpalatal skeletal distractor and Le Fort I surgery. The extraoral characteristics improved and a good occlusal relationship between maxillary and mandibular teeth was achieved.1 juni 201
Retinoic acid signalling in the development of the epidermis, the limbs and the secondary palate
Retinoic acid (RA), the active derivative of vitamin A, is one of the major regulators of embryonic development, including the development of the epidermis, the limbs and the secondary palate. In the embryo, RA levels are tightly regulated by the activity of RA synthesizing and degrading enzymes. Aberrant RA levels due to genetic variations in RA metabolism pathways contribute to congenital malformations in these structures. In vitro and in vivo studies provide considerable evidence on the effects of RA and its possible role in the development of the epidermis, the limbs and the secondary palate. In conjunction with other regulatory factors, RA seems to stimulate the development of the epidermis by inducing proliferation and differentiation of ectodermal cells into epidermal cells. In the limbs, the exact timing of RA location and level is crucial to initiate limb bud formation and to allow chondrogenesis and subsequent osteogenesis. In the secondary palate, the correct RA concentration is a key factor for mesenchymal cell proliferation during palatal shelf outgrowth, elevation and adhesion, and finally to allow bone formation in the hard palate. These findings are highly relevant to understanding the mechanism of RA signalling in development and in the aetiology of specific congenital diseases