Spatiotemporal chaotic dynamics of solitons with internal structure in the presence of finite-width inhomogeneities

We present an analytical and numerical study of the Klein-Gordon kink-soliton dynamics in inhomogeneous media. In particular, we study an external field that is almost constant for the whole system but that changes its sign at the center of coordinates and a localized impurity with finite-width. The soliton solution of the Klein-Gordon-like equations is usually treated as a structureless point-like particle. A richer dynamics is unveiled when the extended character of the soliton is taken into account. We show that interesting spatiotemporal phenomena appear when the structure of the soliton interacts with finite-width inhomogeneities. We solve an inverse problem in order to have external perturbations which are generic and topologically equivalent to well-known bifurcation models and such that the stability problem can be solved exactly. We also show the different quasiperiodic and chaotic motions the soliton undergoes as a time-dependent force pumps energy into the traslational mode of the kink and relate these dynamics with the excitation of the shape modes of the soliton.Comment: 10 pages Revtex style article, 22 gziped postscript figures and 5 jpg figure

Novel compound mutations in the mitochondrial translation elongation factor (TSFM) gene cause severe cardiomyopathy with myocardial fibro-adipose replacement

Primary mitochondrial dysfunction is an under-appreciated cause of cardiomyopathy, especially when cardiac symptoms are the unique or prevalent manifestation of disease. Here, we report an unusual presentation of mitochondrial cardiomyopathy, with dilated phenotype and pathologic evidence of biventricular fibro-adipose replacement, in a 33-year old woman who underwent cardiac transplant. Whole exome sequencing revealed two novel compound heterozygous variants in the TSFM gene, coding for the mitochondrial translation elongation factor EF-Ts. This protein participates in the elongation step of mitochondrial translation by binding and stabilizing the translation elongation factor Tu (EF-Tu). Bioinformatics analysis predicted a destabilization of the EF-Ts variants complex with EF-Tu, in agreement with the dramatic steady-state level reduction of both proteins in the clinically affected myocardium, which demonstrated a combined respiratory chain enzyme deficiency. In patient fibroblasts, the decrease of EF-Ts was paralleled by up-regulation of EF-Tu and induction of genes involved in mitochondrial biogenesis, along with increased expression of respiratory chain subunits and normal oxygen consumption rate. Our report extends the current picture of morphologic phenotypes associated with mitochondrial cardiomyopathies and confirms the heart as a main target of TSFM dysfunction. The compensatory response detected in patient fibroblasts might explain the tissue-specific expression of TSFM-associated disease

Environmental Behaviour of Metolachlor and Diuron in a Tropical Soil in the Central Region of Brazil.

The environmental behaviour of metolachlor and diuron was studied in the Central-western region of Brazil, by means of a field study where six experimental plots were installed. The soil was classified as a Latosol, and the soil horizons were characterized. Sorption of metolachlor and diuron was evaluated in laboratory batch experiments. Metolachlor and diuron were applied to the experimental plots on uncultivated soil in October 2003. From this date to March 2004, the following processes were studied: leaching, runoff and dissipation in top soil. Koc of metolachlor varied from 179 to 264 mL g?1 in the soil horizons. Koc of diuron in the Ap horizon was 917 mL g?1, decreasing significantly in the deeper horizons. Field dissipation half-lives of metolachlor and diuron were 18 and 15 days, respectively. In percolated water, metolachlor was detected in concentrations ranging from 0.02 to 2.84 ?g L?1. In runoff water and sediment, metolachlor was detected in decreasing concentrations throughout the period of study. Losses of 0.02% and 0.54% of the applied amount by leaching and runoff, respectively, were observed confirming the high mobility of this herbicide in the environment. In percolated water, diuron was detected with low frequency but in relatively high concentrations (up to 6.29 ?g L?1). In runoff water and soil, diuron was detected in decreasing concentrations until 70 days after application, totalizing 13.9% during the whole sampling period. These results show the importance of practices to reduce runoff avoiding surface water contamination by these pesticides, particularly diuron

Environmental behaviour of metolachlor and diuron in a tropical soil in the Central Region of Brazil.

The environmental behaviour of metolachlor and diuron was studied in the Central-western region of Brazil, by means of a field study where six experimental plots were installed. The soil was classified as a Latosol, and the soil horizons were characterized. Sorption of metolachlor and diuron was evaluated in laboratory batch experiments. Metolachlor and diuron were applied to the experimental plots on uncultivated soil in October 2003. From this date to March 2004, the following processes were studied: leaching, runoff and dissipation in top soil. K oc of metolachlor varied from 179 to 264 mL g-1 in the soil horizons. K oc of diuron in the Ap horizon was 917 mL g-1, decreasing significantly in the deeper horizons. Field dissipation half-lives of metolachlor and diuron were 18 and 15 days, respectively. In percolated water, metolachlor was detected in concentrations ranging from 0.02 to 2.84 ?g L-1. In runoff water and sediment, metolachlor was detected in decreasing concentrations throughout the period of study. Losses of 0.02% and 0.54% of the applied amount by leaching and runoff, respectively, were observed confirming the high mobility of this herbicide in the environment. In percolated water, diuron was detected with low frequency but in relatively high concentrations (up to 6.29 ?g L-1). In runoff water and soil, diuron was detected in decreasing concentrations until 70 days after application, totalizing 13.9% during the whole sampling period. These results show the importance of practices to reduce runoff avoiding surface water contamination by these pesticides, particularly diuron

Configuration Complexities of Hydrogenic Atoms

The Fisher-Shannon and Cramer-Rao information measures, and the LMC-like or shape complexity (i.e., the disequilibrium times the Shannon entropic power) of hydrogenic stationary states are investigated in both position and momentum spaces. First, it is shown that not only the Fisher information and the variance (then, the Cramer-Rao measure) but also the disequilibrium associated to the quantum-mechanical probability density can be explicitly expressed in terms of the three quantum numbers (n, l, m) of the corresponding state. Second, the three composite measures mentioned above are analytically, numerically and physically discussed for both ground and excited states. It is observed, in particular, that these configuration complexities do not depend on the nuclear charge Z. Moreover, the Fisher-Shannon measure is shown to quadratically depend on the principal quantum number n. Finally, sharp upper bounds to the Fisher-Shannon measure and the shape complexity of a general hydrogenic orbital are given in terms of the quantum numbers.Comment: 22 pages, 7 figures, accepted i

Teaching Modern Languages on Ancient Roots. Anche le pietre parlano

Possono le pietre raccontarci qualcosa? Si possono imparare le lingue osservando i resti archeologici di Verona, Tarragona e Kalamata? Perché le lingue hanno una storia? Perché abbiamo bisogno di rappresentare le parole? In questo volume poniamo anche altri interrogativi e cerchiamo alcune risposte

Synchronicity of thermogenic activity, alternative pathway respiratory flux, AOX protein content, and carbohydrates in receptacle tissues of sacred lotus during floral development

The relationships between heat production, alternative oxidase (AOX) pathway flux, AOX protein, and carbohydrates during floral development in Nelumbo nucifera (Gaertn.) were investigated. Three distinct physiological phases were identified: pre-thermogenic, thermogenic, and post-thermogenic. The shift to thermogenic activity was associated with a rapid, 10-fold increase in AOX protein. Similarly, a rapid decrease in AOX protein occurred post-thermogenesis. This synchronicity between AOX protein and thermogenic activity contrasts with other thermogenic plants where AOX protein increases some days prior to heating. AOX protein in thermogenic receptacles was significantly higher than in post-thermogenic and leaf tissues. Stable oxygen isotope measurements confirmed that the increased respiratory flux supporting thermogenesis was largely via the AOX, with little or no contribution from the cytochrome oxidase pathway. During the thermogenic phase, no significant relationship was found between AOX protein content and either heating or AOX flux, suggesting that regulation is likely to be post-translational. Further, no evidence of substrate limitation was found; starch accumulated during the early stages of floral development, peaking in thermogenic receptacles, before declining by 89% in post-thermogenic receptacles. Whilst coarse regulation of AOX flux occurs via protein synthesis, the ability to thermoregulate probably involves precise regulation of AOX protein, most probably by effectors such as α-keto acids.Nicole M. Grant, Rebecca E. Miller, Jennifer R. Watling and Sharon A. Robinso

A mathematical and computational review of Hartree-Fock SCF methods in Quantum Chemistry

We present here a review of the fundamental topics of Hartree-Fock theory in Quantum Chemistry. From the molecular Hamiltonian, using and discussing the Born-Oppenheimer approximation, we arrive to the Hartree and Hartree-Fock equations for the electronic problem. Special emphasis is placed in the most relevant mathematical aspects of the theoretical derivation of the final equations, as well as in the results regarding the existence and uniqueness of their solutions. All Hartree-Fock versions with different spin restrictions are systematically extracted from the general case, thus providing a unifying framework. Then, the discretization of the one-electron orbitals space is reviewed and the Roothaan-Hall formalism introduced. This leads to a exposition of the basic underlying concepts related to the construction and selection of Gaussian basis sets, focusing in algorithmic efficiency issues. Finally, we close the review with a section in which the most relevant modern developments (specially those related to the design of linear-scaling methods) are commented and linked to the issues discussed. The whole work is intentionally introductory and rather self-contained, so that it may be useful for non experts that aim to use quantum chemical methods in interdisciplinary applications. Moreover, much material that is found scattered in the literature has been put together here to facilitate comprehension and to serve as a handy reference.Comment: 64 pages, 3 figures, tMPH2e.cls style file, doublesp, mathbbol and subeqn package

Determinação de pesticidas em água de poços tubulares em áreas de cultura de algodão na microrregião de primavera do leste, Mato Grosso.

O presente trabalho objetivou realizar uma avaliação preliminar da presença de pesticidas em poços tubulares em 5 áreas de cultura de algodão na região de Primavera do Leste. A caracterização da cobertura pedológica foi efetuada através da elaboração de toposseqüências. A geologia do local dos poços é representada por material argilo-arenoso com concreções ferruginosas da Cobertura Detrito-Laterítica. Foi realizado um levantamento dos pesticidas usados na cultura do algodão, cuja seleção baseou-se em suas propriedades físico-químicas e índices GUS e LIX. Foram realizadas quatro etapas de coleta de amostras de água nos meses de abril, agosto e novembro de 2002 e fevereiro de 2003. O método de análise consistiu na extração em fase sólida das amostras de água com determinação por CG/EM e HPLC/DAD. Dentre os pesticidas analisados foram detectados a atrazina, metolacloro, carbofuram, parationa-metílica, imidacloprido e diurom, com concentrações máximas de 0,07; 0,41; 1,08; 0,17; 3,41 e 2,00 µg L-1, respectivamente. Apesar dos pesticidas terem sido detectados em concentrações baixas, uma vez que os fatores responsáveis pela degradação destas substâncias estão ou ausentes ou presentes em muito menor intensidade nas camadas mais profundas do solo, a presença destas substâncias em águas subterrâneas é um indicativo da sua vulnerabilidade à contaminação