Exploring the Heidelberg Retinal Tomograph 3 diagnostic accuracy across disc sizes and glaucoma stages: a multicenter study

To investigate and compare the diagnostic accuracy of the Heidelberg Retinal Tomograph 3 (HRT3) diagnostic algorithms and establish whether they are affected by optic disc size and glaucoma severity

Survey on retinopathy of prematurity (ROP) in Italy

This study aims to investigate the incidence and the relative risk factors of retinopathy of prematurity (ROP) and posterior-ROP (P-ROP): ROP in Zone I and posterior Zone II, as well as to analyze the occurrence of surgical treatment of ROP and to evaluate the short term outcome of the disease in Italy

Agreement in detecting glaucomatous visual field progression by using guided progression analysis ?and Humphrey overview printout.

To examine the level of agreement among 3 clinicians in assessing glaucoma visual field progression by using 2 different methods.Each visual field was assessed by Humphrey Field Analyzer (HFA), program SITA standard 30-2 or 24-2. In each printout the first 3 fields were excluded to minimize learning effect: the fourth and fifth full-threshold or SITA Standard examinations were used as baseline. Three clinicians assessed the progression status of each series using both HFA overview printouts and the guided progression analysis (GPA). The level of agreement among the clinicians was evaluated using a weighted kappa statistic (k).A total of 510 tests, comprising 83 eyes with an average of 6.1 tests each, was assessed by the 3 specialists. The mean follow-up time was 5.8 \ub1 1.75 years (mean \ub1 standard deviation). When the intraobserver intermethod agreement was evaluated, k ranged from 0.5 to 0.7. When the interobserver agreement was analyzed, if HFA overview printouts were used, k ranged from 0.4 to 0.7. But when GPA was used, k ranged from 0.2 to 0.6. The level of agreement on progression status between the clinicians was always higher when they used HFA overview printouts (median k = 0.54) than when they used GPA (median k = 0.37).Agreement among expert clinicians about visual field progression status was moderate when GPA printouts were used. Clinicians' agreement about patients' visual field progression status was better when HFA overview printouts were used than with GPA printouts

Evaluation of threshold estimation and learning effect of two perimetric strategies, SITA Fast and CLIP, in damaged visual fields.

PURPOSE. The threshold estimation, learning effect, and between-algorithm differences of the Fast Swedish Interactive Thresholding Algorithm (SITA Fast), of the Humphrey Field Analyzer (HFA), and the Continuous Light Increment Perimetry (CLIP) strategy of the Oculus Twinfield perimeter were evaluated in damaged visual fields. METHODS. Twenty-one glaucomatous patients with damaged visual fields (MD worse than \u20138 dB) underwent Oculus Full Threshold (FT), Humphrey FT, SITA Fast, and CLIP 30-2 perimetric examinations. All the tests were repeated in a second session at least 3 days later. The point-wise differences in absolute sensitivity and of the total deviation plot values between FT and fast algorithms, between fast algorithms and the learning effect were evaluated (Wilcoxon test and Bland-Altman analysis). RESULTS. The average point-wise sensitivity difference between SITA Fast and HFA FT strategy (0.84 dB) was significantly lower than that found between CLIP and Oculus FT strategy (1.71 dB). Between- algorithm point-wise differences of the total deviation plot values of the fast strategies were not significantly different. Learning effect for SITA Fast (0.67 dB) was higher than that found for CLIP (0.39 dB). Test time for SITA (367\ub171 sec) and CLIP (453\ub198 sec) were about 55% and 35%, respectively, shorter (p<0.001) than those found with FT algorithms. The acceptance for fast algorithms and particularly for CLIP was significantly better. CONCLUSIONS. The two fast strategies, even though using very different algorithms, showed good threshold estimation compared to FT strategies with a consistent time saving in damaged visual fields