Deep Electrical Resistivity Tomography for the Hydrogeological Setting of Muro Lucano Mounts Aquifer (Basilicata, Southern Italy)

The proposed work concerns the application of a deep geoelectrical survey to a carbonate aquifer in order to define the best location for exploitation well drilling for increasing water supply. However, an optimal characterization of a groundwater resource is the necessary condition to reach the indicated aim. Therefore, the geoelectrical investigation was guided from the previous geological and hydrogeological characterization. Moreover, geophysical methods are good tools to improve the groundwater model when detailed information is necessary, such as the localization of a pumping well. The work summarizes the hydrogeological knowledge at the West of the Basilicata Region (Muro Lucano, Italy). The investigated area is characterized by the presence of a karst aquifer which is made up of a carbonate ridge (Castelgrande, Muro Lucano) that tectonically dips southward and is widely covered by Pliocene deposits (sands and conglomerates), by the Irpinian unit and Sicilide unit formations, and by debris slope and landslide deposits. The assessment of the complex hydrogeological framework of the area was detailed by the use of a new multichannel deep geoelectrical technique (DERT). In details, the proposed technique was able to successfully locate a less resistive zone connected to a more fractured limestone and then it was suitable for the localization of a groundwater exploitation well

Cognitive-Behavioral Treatment of Social Anxiety Disorder and Comorbid Paranoid Schizophrenia

We report on the cognitive-behavioral treatment (CBT) of a patient with comorbid social anxiety disorder (SAD), schizophrenia, and major depressive disorder, complicated by alcohol abuse. Symptoms included auditory hallucinations that commented on the patient’s behavior and paranoid thoughts. The paranoid symptoms affected his social interactions as this included the fear that his thoughts may be heard and judged by others. Therapeutic activities raised awareness as to how avoidance interferes with and perpetuates the cycle of depression and psychosis while maintaining symptoms of SAD. Psychoeducation was provided about factors that maintain social anxiety and increase social isolation. New skills were obtained by helping the patient discover alternative ways to view social situations, experimentation, and real-world application to disprove notions about others’ predicted behavior. Treatment led to a great reduction in social anxiety, depression, and suspicious thinking. This case study demonstrates that SAD symptoms in a patient experiencing psychosis can be effectively treated using CBT

Cognitive-Behavioral Treatment of Social Anxiety Disorder and Comorbid Paranoid Schizophrenia

We report on the cognitive-behavioral treatment (CBT) of a patient with comorbid social anxiety disorder (SAD), schizophrenia, and major depressive disorder, complicated by alcohol abuse. Symptoms included auditory hallucinations that commented on the patient’s behavior and paranoid thoughts. The paranoid symptoms affected his social interactions as this included the fear that his thoughts may be heard and judged by others. Therapeutic activities raised awareness as to how avoidance interferes with and perpetuates the cycle of depression and psychosis while maintaining symptoms of SAD. Psychoeducation was provided about factors that maintain social anxiety and increase social isolation. New skills were obtained by helping the patient discover alternative ways to view social situations, experimentation, and real-world application to disprove notions about others’ predicted behavior. Treatment led to a great reduction in social anxiety, depression, and suspicious thinking. This case study demonstrates that SAD symptoms in a patient experiencing psychosis can be effectively treated using CBT

AI-aided holographic flow cytometry for label-free identification of ovarian cancer cells in the presence of unbalanced datasets

Liquid biopsy is a valuable emerging alternative to tissue biopsy with great potential in the noninvasive early diagnostics of cancer. Liquid biopsy based on single cell analysis can be a powerful approach to identify circulating tumor cells (CTCs) in the bloodstream and could provide new opportunities to be implemented in routine screening programs. Since CTCs are very rare, the accurate classification based on high-throughput and highly informative microscopy methods should minimize the false negative rates. Here, we show that holographic flow cytometry is a valuable instrument to obtain quantitative phase-contrast maps as input data for artificial intelligence (AI)-based classifiers. We tackle the problem of discriminating between A2780 ovarian cancer cells and THP1 monocyte cells based on the phase-contrast images obtained in flow cytometry mode. We compare conventional machine learning analysis and deep learning architectures in the non-ideal case of having a dataset with unbalanced populations for the AI training step. The results show the capacity of AI-aided holographic flow cytometry to discriminate between the two cell lines and highlight the important role played by the phase-contrast signature of the cells to guarantee accurate classification

Nuovi dati su Kossyra ellenistica: dalla ridefinizione urbanistica di III sec. a.C. alla fortezza di Sesto Pompeo

Si presentano le più recenti ricerche a Pantelleria, focalizzando l'attenzione sull'impianto urbano ellenistico e in particolare sulla fortezza che nel I sec.a.C. stravolge parte della città alta. In base alla cronologia del manufatto architettonico e alla lettura delle fonti letterarie di attribuisce l'intervento a Sesto Pompe

Nuovi dati su Kossyra ellenistica: dalla ridefinizione urbanistica di III sec. a.C. alla fortezza di Sesto Pompeo

Si presentano le più recenti ricerche a Pantelleria, focalizzando l'attenzione sull'impianto urbano ellenistico e in particolare sulla fortezza che nel I sec.a.C. stravolge parte della città alta. In base alla cronologia del manufatto architettonico e alla lettura delle fonti letterarie di attribuisce l'intervento a Sesto Pompe

The pre-Roman hilltop settlement of Monte Torretta di Pietragalla: preliminary results of the geophysical survey

Monte Torretta (Pietragalla, PZ) represents one of the most interesting and less known settlements of ancient Lucania. The site was investigated in the last 50 years by several archaeological activities, but no result has been published so far. In order to study and disseminate the archaeological value of the site, the Université Paris 1 Panthéon-Sorbonne and the Humboldt-Universität zu Berlin has established the joint Pietragalla Project. The project is based on a multidisciplinary approach, which aims at studying the settlement and at recovering the lost information obtained by the previous archaeological works. The first geophysical activities conducted on the site offer important results, which increase the knowledge of the site and will help the archaeologists in their future investigation. Through the comparison and integration of different geophysical methodologies, including ground penetrating radar, electrical resistivity tomography and geomagnetic measurements, various information was obtained in proximity of the fortification walls and the two main gates of the site. Moreover, geological and geomorphological interpretations highlighted important information on the archaeological site. The obtained results show the importance of geophysical activities in a context strongly damaged by rural activities of the last century. From an archaeological point of view, the geophysical surveys conducted in 2017 and 2018 show a dense building activity within the area enclosed by the walls. Thanks to these results, we are now able to understand the settlement pattern in the longue durée, at the least for the western part of the infra-muros area