Recent advances: rheumatology

No abstract available

Recent advances: rheumatology

No abstract available

A new capacitance medium for presumptive detection of Listeria spp. from cheese samples

The paper presents a new medium and a method for the rapid presumptive detection of Listeria spp. in cheese samples by electrical capacitance changes. The Bactometer based capacitance broth (LED medium) required a 30% change in signal within 30 h to identify presumptive positive results. Of 32 cheese samples tested, 10 were found to contain Listeria spp. using a Fraser broth screening method and 12 using the LED medium and method. The LED method also gave 16 fewer (total = 1) false presumptive positive results. Results show the LED method to be superior to Fraser broth in regard to both the number of false presumptive positive and confirmed false negative results detected. The method appears to be suitable as a reliable rapid screen for the presence of Listeria spp. in cheese

Human longevity and common variations in the LMNA gene: a meta‐analysis

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92016/1/j.1474-9726.2012.00808.x.pd

Evaluación de la calidad de los materiales educativos digitales aplicados a la enseñanza del Inglés como lengua extranjera.

El desarrollo tecnológico de las últimas décadas ha permitido la implementación de dispositivos cada vez más avanzados en los espacios educativos formales. Estos dispositivos se han constituido en una herramienta fértil para potenciar situaciones de aprendizaje. En los últimos años, las tecnologías de la información y de la comunicación (TIC) han atravesado un período de cuestionamiento sobre su rol e impacto en los procesos de enseñanza y de aprendizaje, generando - tanto en los docentes como en los alumnos - reacciones diversas. Sin embrago, en la actualidad, ya han adquirido un sentido dentro de las prácticas pedagógicas a través de la implementación de las aulas virtuales. No obstante, creemos que la presencia de las TIC, por sí sola, no es garantía de mejora de la calidad de los procesos de enseñanza y de aprendizaje, ya que no todos los tecnofactos cumplen los requisitos de aprovechamiento pedagógico. Por lo tanto, es necesario reflexionar sobre la calidad de dichos instrumentos. En este sentido, el objetivo central de esta comunicación es presentar los resultados de un proyecto de investigación llevado a cabo en la Facultad de Lenguas durante el período 2014-2015, entre cuyos objetivos podemos mencionar los siguientes: (i) definir las características generales de los materiales educativos multimedia; (ii) elaborar criterios consensuados de evaluación que contribuyan a mejorar la calidad de las aulas virtuales destinadas a la enseñanza del inglés como lengua extranjera; (iii) aplicar dichos criterios para detectar fortalezas y debilidades; (iv) diseñar estrategias pedagógicas que contribuyan a superar las debilidades que pudieran haberse detectado.Fil: Negrelli, Fabián H. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Morchio, María José. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Capell, Martín Salvador. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Fil: Ferreras, Cecilia R. Universidad Nacional de Córdoba. Facultad de Lenguas; Argentina.Otras Lengua y Literatur

Sex-Based Differences in Outcomes Following Peripheral Artery Revascularization: Insights From VOYAGER PAD.

Background Despite high female prevalence of peripheral artery disease (PAD), little is known about sex-based outcomes after lower extremity revascularization (LER) for symptomatic PAD. The effects of rivaroxaban according to sex following LER have not been fully reported. Methods and Results In VOYAGER PAD (Vascular Outcomes Study of ASA [acetylsalicylic acid] Along with Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease), low-dose rivaroxaban versus placebo on a background of aspirin reduced the composite primary efficacy outcome of cardiovascular and limb events in patients with PAD undergoing LER. Unplanned index limb revascularization was prespecified and prospectively ascertained. The primary safety outcome was Thrombolysis in Myocardial Infarction major bleeding. Analyses of outcomes and treatment effects by sex were performed using Cox proportional hazards models. Among 6564 randomly assigned patients followed for a median of 28 months, 1704 (26.0%) were women. Among patients administered placebo, women were at similar risk for the primary efficacy outcome (hazard ratio [HR], 0.90; [95% CI, 0.74-1.09]; P=0.29) as men, while female sex was associated with a trend toward higher risk of unplanned index limb revascularization (HR, 1.18; [95% CI, 1.00-1.40]; P=0.0499). Irrespective of sex, effects of rivaroxaban were consistent for the primary efficacy outcome (P-interaction=0.22), unplanned index limb revascularization (P-interaction=0.64), and bleeding (P-interaction=0.61). Women were more likely than men to discontinue study treatment (HR, 1.13; [95% CI, 1.03-1.25]; P=0.0099). Conclusions Among >1700 women with PAD undergoing LER, women and men were at similar risk for the primary outcome, but a trend for greater risk of unplanned index limb revascularization among women was observed. Effects of rivaroxaban were consistent by sex, though women more often discontinued treatment. Better understanding of sex-based outcomes and treatment adherence following LER is needed. Registration URL: http://clinicaltrials.gov; Unique identifier: NCT02504216