Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states

The brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. We address these questions by investigating the brain\u27s intrinsic timescales in healthy controls, motor (amyotrophic lateral sclerosis, locked-in syndrome), sensory (anesthesia, unresponsive wakefulness syndrome), and progressive reduction of sensory processing (from awake states over N1, N2, N3). We employed a combination of measures from EEG resting-state data: auto-correlation window (ACW), power spectral density (PSD), and power-law exponent (PLE). Prolonged neural timescales accompanied by a shift towards slower frequencies were observed in the conditions with sensory deficits, but not in conditions with motor deficits. Our results establish that the spontaneous activity\u27s intrinsic neural timescale is related to the neural capacity that specifically supports sensory rather than motor information processing in the healthy brain

Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states

The brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. We address these questions by investigating the brain\u27s intrinsic timescales in healthy controls, motor (amyotrophic lateral sclerosis, locked-in syndrome), sensory (anesthesia, unresponsive wakefulness syndrome), and progressive reduction of sensory processing (from awake states over N1, N2, N3). We employed a combination of measures from EEG resting-state data: auto-correlation window (ACW), power spectral density (PSD), and power-law exponent (PLE). Prolonged neural timescales accompanied by a shift towards slower frequencies were observed in the conditions with sensory deficits, but not in conditions with motor deficits. Our results establish that the spontaneous activity\u27s intrinsic neural timescale is related to the neural capacity that specifically supports sensory rather than motor information processing in the healthy brain

Are intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states

The brain exhibits a complex temporal structure which translates into a hierarchy of distinct neural timescales. An open question is how these intrinsic timescales are related to sensory or motor information processing and whether these dynamics have common patterns in different behavioral states. We address these questions by investigating the brain\u27s intrinsic timescales in healthy controls, motor (amyotrophic lateral sclerosis, locked-in syndrome), sensory (anesthesia, unresponsive wakefulness syndrome), and progressive reduction of sensory processing (from awake states over N1, N2, N3). We employed a combination of measures from EEG resting-state data: auto-correlation window (ACW), power spectral density (PSD), and power-law exponent (PLE). Prolonged neural timescales accompanied by a shift towards slower frequencies were observed in the conditions with sensory deficits, but not in conditions with motor deficits. Our results establish that the spontaneous activity\u27s intrinsic neural timescale is related to the neural capacity that specifically supports sensory rather than motor information processing in the healthy brain

The atomic gas of star-forming galaxies at z∼\sim0.05 as revealed by the Five-hundred-meter Aperture Spherical Radio Telescope

We report new HI observations of four z$\sim$0.05 star-forming galaxies undertaken during the commissioning phase of the Five-hundred-meter Aperture Spherical Radio Telescope (FAST). FAST is the largest single-dish telescope with a 500 meter aperture and a 19-Beam receiver. Exploiting the unprecedented sensitivity provided by FAST, we aim to study the atomic gas, via the HI 21cm emission line, in low-$z$ star-forming galaxies taken from the Valpara\'iso ALMA/APEX Line Emission Survey (VALES) project. Together with previous ALMA CO($J=1-0$) observations, the HI data provides crucial information to measure the gas mass and dynamics. As a pilot HI survey, we targeted four local star-forming galaxies at $z\sim0.05$. In particular, one of them has already been detected in HI by the Arecibo Legacy Fast ALFA survey (ALFALFA), allowing a careful comparison. We use an ON-OFF observing approach that allowed us to reach an rms of 0.7mJy/beam at a 1.7km/s velocity resolution within only 20 minutes ON-target integration time. We demonstrate the great capabilities of the FAST 19-beam receiver for pushing the detectability of the HI emission line of extra-galactic sources. The HI emission line detected by FAST shows good consistency with the previous ALFALFA results. Our observations are put in context with previous multi-wavelength data to reveal the physical properties of these low-$z$ galaxies. We find that the CO($J=1-0$) and HI emission line profiles are similar. The dynamical mass estimated from the HI data is an order of magnitude higher than the baryon mass and the dynamical mass derived from the CO observations, implying that the mass probed by dynamics of HI is dominated by the dark matter halo. In one case, a target shows an excess of CO($J=1-0$) in the line centre, which can be explained by an enhanced CO($J=1-0$) emission induced by a nuclear starburst showing high velocity dispersion.Comment: 5 pages, 3 figures, 2 appendix, A&A Letter accepte

第944回千葉医学会例会・第1外科教室談話会

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Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite

As China's first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band (1-250 keV) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 MeV. It was designed to perform pointing, scanning and gamma-ray burst (GRB) observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed. Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results.Comment: 29 pages, 40 figures, 6 tables, to appear in Sci. China-Phys. Mech. Astron. arXiv admin note: text overlap with arXiv:1910.0443

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data