Adhesive capsulitis of the shoulder: pain intensity and distribution

Purpose Papers regarding adhesive capsulitis (AC) of the shoulder focused on etiology, epidemiology, diagnosis, and treatment; until now, information on shoulder pain characteristics is still scarce. Our aim was to analyze pain intensity and distribution in patients with AC. Methods The study group was composed of 278 (133M–145F) consecutive patients with AC. After diagnosis, shoulder pain distribution was assessed through an upper limb pain map and pain intensity through a visual analog scale. Patients were distinguished on the basis of gender, age, time elapsed from onset of symptoms, and severity of functional limitation. Data were submitted to statistical analysis. Results Intensity of shoulder pain caused by AC was higher in females (p 0.05). Conclusion Shoulder pain due to AC may be influenced by gender and severity of functional limitation. AC pain distribution principally involves anterior aspect of the shoulder with downward extension of the arm until its distal third

Estimation of synthetic flood design hydrographs using a distributed rainfall–runoff model coupled with a copula-based single storm rainfall generator

In this paper a procedure to derive synthetic flood design hydrographs (SFDH) using a bivariate representation of rainfall forcing (rainfall duration and intensity) via copulas, which describes and models the correlation between two variables independently of the marginal laws involved, coupled with a distributed rainfall–runoff model, is presented. Rainfall–runoff modelling (R–R modelling) for estimating the hydrological response at the outlet of a catchment was performed by using a conceptual fully distributed procedure based on the Soil Conservation Service – Curve Number method as an excess rainfall model and on a distributed unit hydrograph with climatic dependencies for the flow routing. Travel time computation, based on the distributed unit hydrograph definition, was performed by implementing a procedure based on flow paths, determined from a digital elevation model (DEM) and roughness parameters obtained from distributed geographical information. In order to estimate the primary return period of the SFDH, which provides the probability of occurrence of a hydrograph flood, peaks and flow volumes obtained through R–R modelling were treated statistically using copulas. Finally, the shapes of hydrographs have been generated on the basis of historically significant flood events, via cluster analysis. <br><br> An application of the procedure described above has been carried out and results presented for the case study of the Imera catchment in Sicily, Italy

Systems approaches to study root architecture dynamics

The plant root system is essential for providing anchorage to the soil, supplying minerals and water, and synthesizing metabolites. It is a dynamic organ modulated by external cues such as environmental signals, water and nutrients availability, salinity and others. Lateral roots (LRs) are initiated from the primary root post-embryonically, after which they progress through discrete developmental stages which can be independently controlled, providing a high level of plasticity during root system formation. Within this review, main contributions are presented, from the classical forward genetic screens to the more recent high-throughput approaches, combined with computer model predictions, dissecting how LRs and thereby root system architecture is established and developed

Analysis of the Effects of Reservoir Operating Scenarios on Downstream Flood Damage Risk Using an Integrated Monte Carlo Modelling Approach

The aim of this study is to analyse the effects of reservoir operating scenarios, for flood damage evaluation downstream of a dam, using a Monte Carlo bivariate modelling chain. The proposed methodology involves a stochastic procedure to calculate flood hydrographs and the evaluation of the consequent flood inundation area by applying a 2D hydraulic model. These results are used to estimate the inundation risk and, as consequence, the relative damage evaluation under different water level conditions in an upstream reservoir. The modelling chain can be summarized as follows: single synthetic stochastic rainfall event generation by using a Monte Carlo procedure through a bivariate copulas analysis; synthetic bivariate stochastic inflow hydrograph derivation by using a conceptual fully distributed model starting from synthetic hyetographs above the derived; flood hydrographs routing through the reservoir taking in an account of the initial level in the reservoir; flood inundation mapping by applying a 2D hydraulic simulation and damage evaluation through the use of appropriate depth-damage curves. This allowed for the evaluation of the influence of initial water level on flood risk scenarios. The procedure was applied to the case study of the floodplain downstream from the Castello reservoir, within the Magazzolo river catchment, located in the southwestern part of Sicily (Italy)

Effects of fault transmissivity on the potential of fault reactivation and induced seismicity : Implications for understanding induced seismicity at Pohang EGS

Funding Information: The project leading to part of the results in this article received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 691728 .Peer reviewedPublisher PD

Optimal Surface Drainage Inlets Positioning Using Stochastic Pluvial Flooding Analysis

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchive

Interstitial gas and density-segregation in vertically-vibrated granular media

We report experimental studies of the effect of interstitial gas on mass-density-segregation in a vertically-vibrated mixture of equal-sized bronze and glass spheres. Sufficiently strong vibration in the presence of interstitial gas induces vertical segregation into sharply separated bronze and glass layers. We find that the segregated steady state (i.e., bronze or glass layer on top) is a sensitive function of gas pressure and viscosity, as well as vibration frequency and amplitude. In particular, we identify distinct regimes of behavior that characterize the change from bronze-on-top to glass-on-top steady-state.Comment: 4 pages, 5 figures, submitted to PRL; accepted in PRE as rapid communication, with revised text and reference

The Burst-Like Behavior of Aseismic Slip on a Rough Fault: The Creeping Section of the Haiyuan Fault, China

Recent observations suggesting the influence of creep on earthquakes nucleation and arrest are strong incentives to investigate the physical mechanisms controlling how active faults slip. We focus here on deriving generic characteristics of shallow creep along the Haiyuan fault, a major strike‐slip fault in China, by investigating the relationship between fault slip and geometry. We use optical images and time series of Synthetic Aperture Radar data to map the surface fault trace and the spatiotemporal distribution of surface slip along the creeping section of the Haiyuan fault. The fault trace roughness shows a power‐law behavior similar to that of the aseismic slip distribution, with a 0.8 roughness exponent, typical of a self‐affine regime. One possible interpretation is that fault geometry controls to some extent the distribution of aseismic slip, as it has been shown previously for coseismic slip along active faults. Creep is characterized by local fluctuations in rates that we define as creep bursts. The potency of creep bursts follows a power‐law behavior similar to the Gutenberg–Richter earthquake distribution, whereas the distribution of bursts velocity is non‐Gaussian, suggesting an avalanche‐like behavior of these slip events. Such similarities with earthquakes and lab experiments lead us to interpret the rich dynamics of creep bursts observed along the Haiyuan fault as resulting from long‐range elastic interactions within the heterogeneous Earth’s crust

Fault System-Based Probabilistic Seismic Hazard Assessment of a Moderate Seismicity Region: The Eastern Betics Shear Zone (SE Spain)

Including faults as seismogenic sources in probabilistic seismic hazard assessments (PSHA) has turned into a common practice as knowledge of active faults is improving. Moreover, the occurrence of earthquakes in multi-fault ruptures has evidenced the need to understand faults as interacting systems rather than independent sources. We present a PSHA for the Southeastern Spain obtained by including the faults of a moderate seismicity region, the Eastern Betics Shear Zone (EBSZ) in SE Spain, as the main seismogenic sources in two separate source models, one considering background seismicity. In contrast with previous studies in Spain, earthquake occurrence of the EBSZ system is modeled considering different hypotheses of multi-fault ruptures at the whole fault system scale and weighted in a logic tree. We compare the hazard levels with those from an area source PSHA and a previous fault-based approach. The results show a clear control of the EBSZ faults in the seismic hazard for all return periods, increasing drastically the hazard levels in the regions close to the fault traces and influencing up to 20 km farther with respect to the area source PSHA. The seismic hazard is dependent on the fault slip rates as peak ground accelerations and territorial extension of the fault influence appear higher around the Alhama de Murcia and Carboneras faults, while lower slip rate faults (Palomares Fault) show minor contribution to the hazard. For the return period of 475 years and near-fault locations, our models are more consistent with the ground motion values reached in the 2011 Mw 5.2 Lorca event than the building code or national seismic hazard map, which suggest that our fault system-based model performs more accurate estimations for this return period. Fault data, mainly slip rates, and its uncertainties have a clear impact on the seismic hazard and, for some faults, the lack of detailed paleoseismic studies can compromise the reliability of the hazard estimations. This, together with epistemic uncertainties concerning the background seismicity, are key discussion points in the present study, having an impact on further research and aiming to serve as a case example for other low-to-moderate seismicity regions worldwide

Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII

Gram-positive surface proteins can be covalently or non-covalently anchored to the cell wall and can impart important properties on the bacterium in respect of cell envelope organisation and interaction with the environment. We describe here a mechanism of protein anchoring involving tandem CWB2 motifs found in a large number of cell wall proteins in the Firmicutes. In the Clostridium difficile cell wall protein family, we show the three tandem repeats of the CWB2 motif are essential for correct anchoring to the cell wall. CWB2 repeats are non-identical and cannot substitute for each other, as shown by the secretion into the culture supernatant of proteins containing variations in the patterns of repeats. A conserved Ile Leu Leu sequence within the CWB2 repeats is essential for correct anchoring, although a preceding proline residue is dispensable. We propose a likely genetic locus encoding synthesis of the anionic polymer PSII and, using RNA knock-down of key genes, reveal subtle effects on cell wall composition. We show that the anionic polymer PSII binds two cell wall proteins, SlpA and Cwp2, and these interactions require the CWB2 repeats, defining a new mechanism of protein anchoring in Gram-positive bacteria