224,611 research outputs found
End-of-life care: questions and answers
6 pages.Answers typical questions that a terminally ill patient or their caregivers may have
Americans Are Living with Breast Cancer: Projects Report
https://digitalcommons.cwu.edu/government_posters/1154/thumbnail.jp
Enhancing patient safety and quality of surgical cancer care: The French National Cancer Plans
Efforts toward Identifying the Binding Site of an Inhibitor of Human Polynucleotide Kinase/Phosphatase using an Imidopiperidine Inhibitor by Photoaffinity Labelling
EFSA Panel on Food Contact Material, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 73, Revision 1: Consideration of alicyclic primary alcohols, aldehydes, acids and related esters evaluated by JECFA (59th meeting) structurally related to primary saturated or unsaturated alicyclic alcohol, aldehyde, and esters evaluated by EFSA in FGE.12Rev2 (2011)
A retrospective cohort study of the influence of lifestyle factors on survival of patients undergoing surgery for colorectal cancer.
Aim:
Several modifiable and non-modifiable health related behaviours are associated with the incidence of Colorectal Cancer (CRC), but there is little research on their association with survival. The project aimed to investigate possible relationships between modifiable behavioural factors and outcomes on a study cohort of CRC patients undergoing potentially curative surgery.
Method:
A retrospective cohort study was carried out of patients diagnosed with non-metastatic CRC undergoing elective curative surgery (January 2011 - December 2012), residing in the NHS Greater Glasgow & Clyde (NHSGGC) area, UK. Data were obtained from the Scottish Cancer Registry, National Scottish Death Records. Pre-operative assessment of smoking, alcohol consumption, nurse-measured body mass index (BMI) and exercise levels were recorded and patients were followed until death or censorship. Survival analysis was carried out and proportional hazards assumptions were assessed graphically using plots and were then formally tested using the PHTEST procedure in STATA.
Results:
Of the initial 527 patients, 181 (34%) satisfied the inclusion criteria. The total duration of follow up was 480 person-years. At the pre-operative assessment, 75% were overweight or obese, 10.6% were current smokers, 13.1% recorded excess alcohol consumption and 8.5% had physical difficulty climbing stairs. Age, BMI, histopathological stage and physical capacity all independently affected survival (P<0.05). Overweight patients (HR 2.81) and those who had difficulty climbing stairs (HR 3.31) had a significantly poorer survival.
Conclusion:
The study found evidence that pre-operative exercise capacity and BMI are important independent prognostic factors of survival in patients undergoing curative surgery for CRC
CRUZA: The Alliance for Latino Health through Faith and Action, A UMass Boston - Dana-Farber/Harvard Cancer Center Partnership for Community-Based Research
CRUZA is a community-based participatory research partnership aimed at shifting the focus from intervention delivery on an individual level to a focus on enhancing the capacity of community organizations. CRUZA intends to activate collective resources to translate scientific evidence into strategies that increase cancer screening among Latinos in Massachusetts
Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL)
<p>Abstract</p> <p>Background</p> <p>Diffuse large B-cell lymphoma (DLBCL) comprises 31% of lymphomas in the United States. Although it is an aggressive type of lymphoma, 40% to 50% of patients are cured with treatment. The study objectives were to identify patient factors associated with treatment and survival in DLBCL.</p> <p>Methods</p> <p>Using Surveillance, Epidemiology, and End Results (SEER) registry data linked to Medicare claims, we identified 7,048 patients diagnosed with DLBCL between January 1, 2001 and December 31, 2005. Patients were followed from diagnosis until the end of their claims history (maximum December 31, 2007) or death. Medicare claims were used to characterize the first infused chemo-immunotherapy (C-I therapy) regimen and to identify radiation. Multivariate analyses were performed to identify patient demographic, socioeconomic, and clinical factors associated with treatment and with survival. Outcomes variables in the survival analysis were all-cause mortality, non-Hodgkin's lymphoma (NHL) mortality, and other/unknown cause mortality.</p> <p>Results</p> <p>Overall, 84% (n = 5,887) received C-I therapy or radiation treatment during the observation period: both, 26%; C-I therapy alone, 53%; and radiation alone, 5%. Median age at diagnosis was 77 years, 54% were female, 88% were white, and 43% had Stage III or IV disease at diagnosis. The median time to first treatment was 42 days, and 92% of these patients had received their first treatment by day 180 following diagnosis. In multivariate analysis, the treatment rate was significantly lower among patients ≥ 80 years old, blacks versus whites, those living in a census tract with ≥ 12% poverty, and extra-nodal disease. Blacks had a lower treatment rate overall (Hazard Ratio [HR] 0.77; P < 0.001), and were less likely to receive treatment within 180 days of diagnosis (Odds Ratio [OR] 0.63; P = 0.002) than whites. In multivariate survival analysis, black race was associated with higher all-cause mortality (HR 1.24; P = 0.01) and other/unknown cause mortality (HR 1.35; P = 0.01), but not mortality due to NHL (HR 1.16; P = 0.19).</p> <p>Conclusions</p> <p>In elderly patients diagnosed with DLBCL, there are large differences in treatment access and survival between blacks and whites.</p
Nutrition and physical activity recommendations for cancer survivors in Scotland: feasibility of a short course to promote behaviour change.
More people are living for longer following a cancer diagnosis, however long-term survivors are more likely to experience chronic illnesses. Improving their diet and physical activity behaviours may increase survival and reduce the risk of cancer recurrence and other non-communicable diseases. The World Cancer Research Fund and American Institute for Cancer Research recommend that cancer survivors aim to be a healthy weight and physically active; eat a diet rich in wholegrains, vegetables, fruits and beans; limit consumption of ‘fast foods’, red and processed meat, sugar sweetened drinks and alcohol; and meet nutritional needs through diet alone rather than relying on supplements. Evidence suggests that cancer survivors are receptive to receiving advice and making dietary and physical activity changes, but barriers to improving the diet and being physically active need to be explored and addressed. We collaborated with CLAN Cancer Support (an independent charity) to assess the feasibility of a two-day course designed to improve diet and physical activity in cancer survivors in Scotland. Further, it explored the barriers and facilitators that cancer survivors identify in relation to eating a healthy diet and being physically active. The course included presentations, practical activities and group discussions. Initial analysis indicates that factors specific to this population need to be designed into the delivery of the course to enhance recruitment and promote behaviour change. Research then needs to be translated into sustainable support programmes accessible by all cancer survivors. This article describes the rationale behind the study, its design and expected outcomes
TARPTAUTINIAI SLAUGYTOJŲ IR AKUŠERIŲ METAI. Gydytojui – dešinioji ranka, pacientui – ramybės uostas: vienos seniausių profesijų prestižas tik auga
Išklausyti, užjausti, patarti – tai tik keli tikslai, kuriuos greta pagrindinių savo profesinių užduočių sau kelia šalies slaugytojai. Daugiausiai laiko šalia paciento (ir jo artimųjų) praleidžiantys slaugytojai visada buvo ypač svarbūs, tačiau šiandien jų vaidmuo dar labiau sustiprėjęs. Apie vienos seniausių pasaulyje profesijų – slaugytojų – svarbą, evoliuciją ir iššūkius specialistai kalbėjo Nacionalinio vėžio instituto ir Lietuvos operacinės slaugytojų draugijos organizuotoje konferencijoje.Išklausyti, užjausti, patarti – tai tik keli tikslai, kuriuos greta pagrindinių savo profesinių užduočių sau kelia šalies slaugytojai. Daugiausiai laiko šalia paciento (ir jo artimųjų) praleidžiantys slaugytojai visada buvo ypač svarbūs, tačiau šiandien jų vaidmuo dar labiau sustiprėjęs. Apie vienos seniausių pasaulyje profesijų – slaugytojų – svarbą, evoliuciją ir iššūkius specialistai kalbėjo Nacionalinio vėžio instituto ir Lietuvos operacinės slaugytojų draugijos organizuotoje konferencijoje
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