Demonstration of the Universality of Molecular Structures in Prolate Deformed Nuclei

The relationship between the deformed harmonic oscillator and the formation of molecular cluster structures, whereby valence neutrons are exchanged between cluster cores, is examined. It is found that there is a strong connection between the properties of the valence orbitals associated with deformed structures in the deformed harmonic oscillator and the molecular orbitals created by linear combinations of single-centre orbitals around nuclear clusters. The conclusion is that in addition to the appearance of clustering in the deformed harmonic oscillator that \emph{every} prolate deformed cluster structure should have molecular orbitals built on that structure. This is demonstrated through a series of examples that range from $^{13}$C to $^{57}$Ni

Optimized Heat Interception for Cryogen Tank Support

We consider means for using the cooling available in boil-off gas to intercept heat conducted through the support structure of a cryogen tank. A one-dimensional model of the structure coupled to a gas stream gives an analytical expression for heat leak in terms of flow rate for temperature independent-properties and laminar flow. A numerical model has been developed for heat transfer on a thin cylindrical tube with an attached vent line. The model is used to determine the vent path layout that will minimize heat flow into the cryogen tank. The results are useful for a number of applications, but the one of interest in this study is the minimization of the boil-off in large cryopropellant tanks in low Earth and low lunar orbit

Change in quality of life for patients with irritable bowel syndrome following referral to a gastroenterologist: a cohort study

BACKGROUND: Irritable bowel syndrome (IBS), a chronic functional condition, considerably reduces quality of life (QoL) and referral to gastroenterology is common. Until now, however, the impact of seeing a gastroenterologist for IBS on patients’ QoL and utility has not been assessed. METHODS: Patients referred with “probable IBS” to the Nottingham Treatment Centre between October 2012 and March 2014 were invited to complete a QoL questionnaire (EuroQol–5 Dimension) before their first appointment. Patients with confirmed IBS who completed this baseline assessment were sent follow-up questionnaires three and twelve months later. Global QoL and utility were measured at each time point and change from baseline calculated. Paired t-tests analysed the significance of any change. RESULTS: Of 205 invited patients, 69 were eligible and recruited. Response at three and twelve months was 45% and 17% respectively. Median global QoL at baseline was 67.5 (Interquartile range [IQR] 50.0 to 80.0), with a mean increase of 3.25 (95% confidence interval [CI] -5.38 to 11.88) three months later and a mean decrease of -1.82 (95% CI -16.01 to 12.38) after one year. The median utility at baseline was 0.76 (IQR 0.69 to 0.80), with a mean increase of 0.06 (95%CI -0.01 to 0.14) at three months and no change, 0.00 (-0.16 to 0.16), after one year. CONCLUSION: Patients experienced a small but not statistically significant increase in QoL and utility three months after seeing a gastroenterologist for IBS, which was not maintained. Gastroenterology referral does not appear to appreciably improve Qol for most people with IBS

The epidemiology of irritable bowel syndrome

Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how this impacts epidemiological measurements. Depending on the diagnostic criteria employed, IBS affects around 11% of the population globally. Around 30% of people who experience the symptoms of IBS will consult physicians for their IBS symptoms. These people do not have significantly different abdominal symptoms to those who do not consult, but they do have greater levels of anxiety and lower quality of life. Internationally, there is a female predominance in the prevalence of IBS. There is 25% less IBS diagnosed in those over 50 years and there is no association with socioeconomic status. IBS aggregates within families and the genetic and sociological factors potentially underlying this are reviewed. Patients diagnosed with IBS are highly likely to have other functional disease and have more surgery than the general population. There is no evidence that IBS is associated with an increased mortality risk. The epidemiological evidence surrounding these aspects of the natural history is discussed

Active Costorage of Cryogenic Propellants for Exploration

Long-term storage of cryogenic propellants is a critical requirement for NASA's effort to return to the moon. Liquid hydrogen and liquid oxygen provide the highest specific impulse of any practical chemical propulsion system, and thus provides the greatest payload mass per unit of launch mass. Future manned missions will require vehicles with the flexibility to remain in orbit for months, necessitating long-term storage of these cryogenic liquids. For decades cryogenic scientific satellites have used cryogens to cool instruments. In many cases, the lifetime of the primary cryogen tank has been extended by intercepting much of the heat incident on the tank at an intermediate-temperature shield cooled either by a second cryogen tank or a mechanical cryocooler. For an LH2/LO2 propellant system, a combination of these ideas can be used, in which the shield around the LO2 tank is attached to, and at the same temperature as, the LO2 tank, but is actively cooled so as to remove all heat impinging on the tank and shield. This configuration eliminates liquid oxygen boil-off and cuts the liquid hydrogen boil-off to a small fraction of the unshielded rate. This paper studies the concept of active costorage as a means of long-term cryogenic propellant storage. The paper describes the design impact of an active costorage system for the Crew Exploration Vehicle (CEV). This paper also compares the spacecraft level impact of the active costorage concept with a passive storage option in relation to two different scales of spacecraft that will be used for the lunar exploration effort, the CEV and the Earth Departure Stage (EDS). Spacecraft level studies are performed to investigate the impact of scaling of the costorage technologies for the different components of the Lunar Architecture and for different mission durations

Thermal Conductivity and Specific Heat Measurements of Candidate Structural Materials for the JWST Optical Bench

The James Webb Space Telescope will include an optical bench known as the integrated science instrument module (ISIM). Candidate structural materials for the ISIM must have low density, high stiffness, high thermal conductivity, and low thermal expansion coefficient at the operating temperature of 30 Kelvin. The specific heat is also important in modeling the on-orbit cooldown. We built two different systems for measuring the thermal conductivity and specific heat of samples between 4 Kelvin and 290 Kelvin. Both experiments were carefully designed to minimize potential errors due to radiative heat transfer. We chose the cooling system and instrumentation to allow long-term unattended operation. Software was developed to automate each experiment. It used an algorithm designed to ensure that each system was in thermal equilibrium before a measurement was taken. We describe the two experiments and present the data

ADR salt pill design and crystal growth process for hydrated magnetic salts

A process is provided for producing a salt pill for use in very low temperature adiabatic demagnetization refrigerators (ADRs). The method can include providing a thermal bus in a housing. The thermal bus can include an array of thermally conductive metal conductors. A hydrated salt can be grown on the array of thermally conductive metal conductors. Thermal conductance can be provided to the hydrated salt

The SDGs Will Require Integrated Agriculture, Nutrition, and Health at the Community Level

Child malnutrition is an urgent and complex issue and requires integrated approaches across agriculture, nutrition, and health. This issue has gained prominence at the global level. While national-level efforts are underway in many countries, there is little information on how to integrate at the community level. Here, we offer a community-based approach using cadres of agricultural and community health workers, drawing on qualitative work we have conducted in Tanzania. Agriculture is an important driver of nutritional and health outcomes, and improving child health will require practical solutions for integration that can add to the evidence base