995 research outputs found
FAST: FAST Analysis of Sequences Toolbox.
FAST (FAST Analysis of Sequences Toolbox) provides simple, powerful open source command-line tools to filter, transform, annotate and analyze biological sequence data. Modeled after the GNU (GNU's Not Unix) Textutils such as grep, cut, and tr, FAST tools such as fasgrep, fascut, and fastr make it easy to rapidly prototype expressive bioinformatic workflows in a compact and generic command vocabulary. Compact combinatorial encoding of data workflows with FAST commands can simplify the documentation and reproducibility of bioinformatic protocols, supporting better transparency in biological data science. Interface self-consistency and conformity with conventions of GNU, Matlab, Perl, BioPerl, R, and GenBank help make FAST easy and rewarding to learn. FAST automates numerical, taxonomic, and text-based sorting, selection and transformation of sequence records and alignment sites based on content, index ranges, descriptive tags, annotated features, and in-line calculated analytics, including composition and codon usage. Automated content- and feature-based extraction of sites and support for molecular population genetic statistics make FAST useful for molecular evolutionary analysis. FAST is portable, easy to install and secure thanks to the relative maturity of its Perl and BioPerl foundations, with stable releases posted to CPAN. Development as well as a publicly accessible Cookbook and Wiki are available on the FAST GitHub repository at https://github.com/tlawrence3/FAST. The default data exchange format in FAST is Multi-FastA (specifically, a restriction of BioPerl FastA format). Sanger and Illumina 1.8+ FastQ formatted files are also supported. FAST makes it easier for non-programmer biologists to interactively investigate and control biological data at the speed of thought
Quantum Criticality in doped CePd_1-xRh_x Ferromagnet
CePd_1-xRh_x alloys exhibit a continuous evolution from ferromagnetism (T_C=
6.5 K) at x = 0 to a mixed valence (MV) state at x = 1. We have performed a
detailed investigation on the suppression of the ferromagnetic (F) phase in
this alloy using dc-(\chi_dc) and ac-susceptibility (\chi_ac), specific heat
(C_m), resistivity (\rho) and thermal expansion (\beta) techniques. Our results
show a continuous decrease of T_C (x) with negative curvature down to T_C = 3K
at x*= 0.65, where a positive curvature takes over. Beyond x*, a cusp in cac is
traced down to T_C* = 25 mK at x = 0.87, locating the critical concentration
between x = 0.87 and 0.90. The quantum criticality of this region is recognized
by the -log(T/T_0) dependence of C_m/T, which transforms into a T^-q (~0.5) one
at x = 0.87. At high temperature, this system shows the onset of valence
instability revealed by a deviation from Vegard's law (at x_V~0.75) and
increasing hybridization effects on high temperature \chi_dc and \rho.
Coincidentally, a Fermi liquid contribution to the specific heat arises from
the MV component, which becomes dominant at the CeRh limit. In contrast to
antiferromagnetic systems, no C_m/T flattening is observed for x > x_cr rather
the mentioned power law divergence, which coincides with a change of sign of
\beta. The coexistence of F and MV components and the sudden changes in the T
dependencies are discussed in the context of randomly distributed magnetic and
Kondo couplings.Comment: 11 pages, 11 figure
Interplay between superconductivity and magnetism in K-doped EuFe2As2
Superconductivity is found in 50% K-doped EuFe2As2 sample below 33 K. Our
results of electrical resistivity, magnetic susceptibility and 57Fe and 151Eu
Mossbauer spectroscopy provide clear evidence that the ordering of the Fe
moments observed at 190 K in undoped EuFe2As2 is completely suppressed in our
50% K doped sample, thus there is no coexistence between the Fe magnetic order
and the superconducting state. However, short range ordering of the Eu moments
is coexisting with the superconducting state below 15 K. A bump in the
susceptibility well below Tc as well as a slight broadening of the Fe Mossbauer
line below 15 K evidence an interplay between the Eu magnetism and the
superconducting state.Comment: 7 pages, 6 figure
Density fluctuations and single-particle dynamics in liquid lithium
The single-particle and collective dynamical properties of liquid lithium
have been evaluated at several thermodynamic states near the triple point. This
is performed within the framework of mode-coupling theory, using a
self-consistent scheme which, starting from the known static structure of the
liquid, allows the theoretical calculation of several dynamical properties.
Special attention is devoted to several aspects of the single-particle
dynamics, which are discussed as a function of the thermodynamic state. The
results are compared with those of Molecular Dynamics simulations and other
theoretical approaches.Comment: 31 pages (in preprint format), 14 figures. Submitted to Phys. Rev.
Superconductive "sodalite"-like clathrate calcium hydride at high pressures
Hydrogen-rich compounds hold promise as high-temperature superconductors
under high pressures. Recent theoretical hydride structures on achieving
high-pressure superconductivity are composed mainly of H2 fragments. Through a
systematic investigation of Ca hydrides with different hydrogen contents using
particle-swam optimization structural search, we show that in the stoichiometry
CaH6 a body-centred cubic structure with hydrogen that forms unusual "sodalite"
cages containing enclathrated Ca stabilizes above pressure 150 GPa. The
stability of this structure is derived from the acceptance by two H2 of
electrons donated by Ca forming a "H4" unit as the building block in the
construction of the 3-dimensional sodalite cage. This unique structure has a
partial occupation of the degenerated orbitals at the zone centre. The
resultant dynamic Jahn-Teller effect helps to enhance electron-phonon coupling
and leads to superconductivity of CaH6. A superconducting critical temperature
(Tc) of 220-235 K at 150 GPa obtained from the solution of the Eliashberg
equations is the highest among all hydrides studied thus far.Comment: 19 pages, 4 figure
Pressure effects on the electron-doped high Tc superconductor BaFe(2-x)Co(x)As(2)
Application of pressures or electron-doping through Co substitution into Fe
sites transforms the itinerant antiferromagnet BaFe(2)As(2) into a
superconductor with the Tc exceeding 20K. We carried out systematic transport
measurements of BaFe(2-x)Co(x)As(2) superconductors in pressures up to 2.5GPa,
and elucidate the interplay between the effects of electron-doping and
pressures. For the underdoped sample with nominal composition x = 0.08,
application of pressure strongly suppresses a magnetic instability while
enhancing Tc by nearly a factor of two from 11K to 21K. In contrast, the
optimally doped x=0.20 sample shows very little enhancement of Tc=22K under
applied pressure. Our results strongly suggest that the proximity to a magnetic
instability is the key to the mechanism of superconductivity in iron-pnictides.Comment: 5 figure
Evidence of two viscous relaxation processes in the collective dynamics of liquid lithium
New inelastic X-ray scattering experiments have been performed on liquid
lithium in a wide wavevector range. With respect to the previous measurements,
the instrumental resolution, improved up to 1.5 meV, allows to accurately
investigate the dynamical processes determining the observed shape of the the
dynamic structure factor, . A detailed analysis of the lineshapes
shows the co-existence of relaxation processes with both a slow and a fast
characteristic timescales, and therefore that pictures of the relaxation
mechanisms based on a simple viscoelastic model must be abandoned.Comment: 5 pages, 4 .PS figure
Sensory Measurements: Coordination and Standardization
Do sensory measurements deserve the label of “measurement”? We argue that they do. They fit with an epistemological view of measurement held in current philosophy of science, and they face the same kinds of epistemological challenges as physical measurements do: the problem of coordination and the problem of standardization. These problems are addressed through the process of “epistemic iteration,” for all measurements. We also argue for distinguishing the problem of standardization from the problem of coordination. To exemplify our claims, we draw on olfactory performance tests, especially studies linking olfactory decline to neurodegenerative disorders
Evidence of short time dynamical correlations in simple liquids
We report a molecular dynamics (MD) study of the collective dynamics of a
simple monatomic liquid -interacting through a two body potential that mimics
that of lithium- across the liquid-glass transition. In the glassy phase we
find evidences of a fast relaxation process similar to that recently found in
Lennard-Jones glasses. The origin of this process is ascribed to the
topological disorder, i.e. to the dephasing of the different momentum
Fourier components of the actual normal modes of vibration of the disordered
structure. More important, we find that the fast relaxation persists in the
liquid phase with almost no temperature dependence of its characteristic
parameters (strength and relaxation time). We conclude, therefore, that in the
liquid phase well above the melting point, at variance with the usual
assumption of {\it un-correlated} binary collisions, the short time particles
motion is strongly {\it correlated} and can be described via a normal mode
expansion of the atomic dynamics.Comment: 7 pages, 7 .eps figs. To appear in Phys. Rev.
Proceedings of the 2nd Workshop on Flavor Symmetries and Consequences in Accelerators and Cosmology (FLASY12)
These are the proceedings of the 2nd Workshop on Flavor Symmetries and
Consequences in Accelerators and Cosmology, held 30 June 2012 - 4 July 2012,
Dortmund, Germany.Comment: Order 400 pages, several figures including the group picture v2:
corrected author list and contributio
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