32 research outputs found

    Predicting Crime Using Spatial Features

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    Our study aims to build a machine learning model for crime prediction using geospatial features for different categories of crime. The reverse geocoding technique is applied to retrieve open street map (OSM) spatial data. This study also proposes finding hotpoints extracted from crime hotspots area found by Hierarchical Density-Based Spatial Clustering of Applications with Noise (HDBSCAN). A spatial distance feature is then computed based on the position of different hotpoints for various types of crime and this value is used as a feature for classifiers. We test the engineered features in crime data from Royal Canadian Mounted Police of Halifax, NS. We observed a significant performance improvement in crime prediction using the new generated spatial features.Comment: Paper accepted to 31st Canadian Conference in Artificial Intelligence, 201

    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

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    In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field

    A topic detection and visualisation system on social media posts

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    Comunicació presentada a: Internet Science. 4th International Conference, INSCI 2017 celebrada del 22 al 24 de novembre de 2017 a Thessaloniki, Grècia.Large amounts of social media posts are produced on a daily basis and monitoring all of them is a challenging task. In this direction we demonstrate a topic detection and visualisation tool in Twitter data, which filters Twitter posts by topic or keyword, in two different languages; German and Turkish. The system is based on state-of-the-art news clustering methods and the tool has been created to handle streams of recent news information in a fast and user-friendly way. The user interface and user-system interaction examples are presented in detail.This work was supported by the EC-funded projects H2020-645012 (KRISTINA) and H2020-700475 (beAWARE)

    Antifungal and marker effects of Talisia esculenta lectin on Microsporum canis in vitro

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    Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Aims: The purpose of this study was to demonstrate the usefulness of lectin obtained from Talisia esculenta (TEL) seeds as a tool to recognize and study Microsporum canis. For this purpose, we investigated the antifungal and marker action of this lectin and the relationship of these effects with the presence of carbohydrates on the structure of this fungus. Methods and Results: The in vitro antifungal activity of TEL was analysed by broth microdilution assay. In addition, TEL was assessed against the arthroconidia present on hairs obtained from infected dogs and cats. The affinity of fluorescein isothiocyanate (FITC)-labelled TEL for macroconidia and arthroconidia of M. canis was also tested. The effects of TEL on the growth of the M. canis strains began with 0 center dot 125 mg ml-1, and 100% inhibition was obtained with a concentration of 2 mg ml-1. The addition of carbohydrates, especially N-acetyl-glucosamine and d-mannose, inhibited these antifungal effects. TEL was able to inhibit the growth of arthroconidial chitin-rich forms of M. canis obtained from hairs of infected animals and strains cultured in Sabouraud agar. FITC-labelled TEL efficiently marked macroconidial and arthroconidial forms of M. canis, as shown by fluorescent microscopy. Conclusions: These results show that the inhibitory effects of TEL on M. canis growth may be related to the interaction of lectin with the carbohydrates present at the micro-organism's surface, mainly d-mannose and N-acetyl-glucosamine. Significance and Impact of the Study: Talisia esculenta can be used as an important tool in the biochemical study of M. canis or as a molecule to recognize this dermatophyte in infected tissue.107620632069Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FUNCAP (Ceara State Research Support Foundation) [9836/06]Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)CNPq [475724/2006-2]FUNCAP (Ceara State Research Support Foundation) [9836/06

    Performance and carcass characteristics of free-range broiler chickens fed diets containing alternative feedstuffs

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    The present study was carried out to evaluate the effects of alternative feedstuffs as partial substitutes of corn and soybean in free-range broiler diets on performance, carcass yield and technical-economic viability. A total of 400 Pescoço Pelado broilers were distributed in a completely randomized experimental design (CRD), with four treatments (treatment 1:Control; treatment 2: 10% rice bran inclusion; treatment 3: 10% ground cassava leaves; and treatment 4: 10% ground lead tree hay) with four replicates per treatment. Each replicate consisted of a group of 25 birds per paddock, separated per sex. Initial weight (IW), final weight (FW), body weight (BW), daily weight gain (DWG), feed intake (FI) and feed conversion ratio (FCR) were evaluated. Carcass, cuts (breast, thigh, drumstick, back, neck, leg and wings), abdominal fat and giblets (gizzard, heart and liver) yields were determined. The technical-economic viability of each treatment was assessed by determining the cost of feed per kg body weight, economic efficiency index and cost. The highest final weights were obtained with the use of rice bran. Rice bran and cassava leaves promoted higher carcass yield, as well as lower back and abdominal fat yields. The use of cassava leaves showed better economic efficiency among the treatments with alternative feedstuffs. The use of alternative feedstuffs at 10% inclusion in substitution of corn and soybean meal did not not result in major changes in performance and carcass parameters, and economic efficiency, and therefore, their use is recommended when the availability or the price of key ingredients, such as soybean meal and corn, increase
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