3,250 research outputs found
High expansion coefficient glasses can be sealed to common metals
New series of high expansion coefficient glasses can be sealed by fusion onto hot surfaces of metals and alloys. Glasses have relatively low working temperatures, good chemical durability, and can be used in electrical insulators and feedthroughs to fluid or vacuum systems
STEPS - an approach for human mobility modeling
In this paper we introduce Spatio-TEmporal Parametric Stepping (STEPS) - a simple parametric mobility model which can cover a large spectrum of human mobility patterns. STEPS makes abstraction of spatio-temporal preferences in human mobility by using a power law to rule the nodes movement. Nodes in STEPS have preferential attachment to favorite locations where they spend most of their time. Via simulations, we show that STEPS is able, not only to express the peer to peer properties such as inter-ontact/contact time and to reflect accurately realistic routing performance, but also to express the structural properties of the underlying interaction graph such as small-world phenomenon. Moreover, STEPS is easy to implement, exible to configure and also theoretically tractable
HAM-5 functions as a MAP kinase scaffold during cell fusion in Neurospora crassa.
Cell fusion in genetically identical Neurospora crassa germlings and in hyphae is a highly regulated process involving the activation of a conserved MAP kinase cascade that includes NRC-1, MEK-2 and MAK-2. During chemotrophic growth in germlings, the MAP kinase cascade members localize to conidial anastomosis tube (CAT) tips every âŒ8 minutes, perfectly out of phase with another protein that is recruited to the tip: SOFT, a recently identified scaffold for the MAK-1 MAP kinase pathway in Sordaria macrospora. How the MAK-2 oscillation process is initiated, maintained and what proteins regulate the MAP kinase cascade is currently unclear. A global phosphoproteomics approach using an allele of mak-2 (mak-2Q100G) that can be specifically inhibited by the ATP analog 1NM-PP1 was utilized to identify MAK-2 kinase targets in germlings that were potentially involved in this process. One such putative target was HAM-5, a protein of unknown biochemical function. Previously, Îham-5 mutants were shown to be deficient for hyphal fusion. Here we show that HAM-5-GFP co-localized with NRC-1, MEK-2 and MAK-2 and oscillated with identical dynamics from the cytoplasm to CAT tips during chemotropic interactions. In the Îmak-2 strain, HAM-5-GFP localized to punctate complexes that did not oscillate, but still localized to the germling tip, suggesting that MAK-2 activity influences HAM-5 function/localization. However, MAK-2-GFP showed cytoplasmic and nuclear localization in a Îham-5 strain and did not localize to puncta. Via co-immunoprecipitation experiments, HAM-5 was shown to physically interact with NRC-1, MEK-2 and MAK-2, suggesting that it functions as a scaffold/transport hub for the MAP kinase cascade members for oscillation and chemotropic interactions during germling and hyphal fusion in N. crassa. The identification of HAM-5 as a scaffold-like protein will help to link the activation of MAK-2 cascade to upstream factors and proteins involved in this intriguing process of fungal communication
Phase Behavior of Bent-Core Molecules
Recently, a new class of smectic liquid crystal phases (SmCP phases)
characterized by the spontaneous formation of macroscopic chiral domains from
achiral bent-core molecules has been discovered. We have carried out Monte
Carlo simulations of a minimal hard spherocylinder dimer model to investigate
the role of excluded volume interations in determining the phase behavior of
bent-core materials and to probe the molecular origins of polar and chiral
symmetry breaking. We present the phase diagram as a function of pressure or
density and dimer opening angle . With decreasing , a transition
from a nonpolar to a polar smectic phase is observed near ,
and the nematic phase becomes thermodynamically unstable for . No chiral smectic or biaxial nematic phases were found.Comment: 4 pages Revtex, 3 eps figures (included
Bound states in the three dimensional phi^4 model
We discuss the spectrum of the three dimensional phi^4 theory in the broken
symmetry phase. In this phase the effective potential between the elementary
quanta of the model is attractive and bound states of two or more of them may
exist. We give theoretical and numerical evidence for the existence of these
bound states. Looking in particular at the Ising model realization of the phi^4
theory we show, by using duality, that these bound states are in one-to-one
correspondence with the glueball states of the gauge Ising model. We discuss
some interesting consequences of this identification.Comment: 4 pages, 3 figures. Numerical value of the preexponential factor in
the binding energy corrected, all other results and conclusions unchange
Magnetization of ferrofluids with dipolar interactions - a Born--Mayer expansion
For ferrofluids that are described by a system of hard spheres interacting
via dipolar forces we evaluate the magnetization as a function of the internal
magnetic field with a Born--Mayer technique and an expansion in the dipolar
coupling strength. Two different approximations are presented for the
magnetization considering different contributions to a series expansion in
terms of the volume fraction of the particles and the dipolar coupling
strength.Comment: 19 pages, 11 figures submitted to PR
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