User interface development and software environments : the Chiron-1 system

User interface development systems for software environments have to cope with the broad, extensible and dynamic character of such environments, must support internal and external integration, and should enable various software development strategies. The Chiron-1 system adapts and extends key ideas from current research in user interface development systems to address the particular demands of software environments. Important Chiron-1 concepts are: separation of concerns, dynamism, and open architecture. We discuss the requirements on such user interface development systems, present the Chiron-1 architecture and a scenario of its usage, detail the concepts it embodies, and report on its design and prototype implementation

Associations between physical activity and BMI, body fatness, and visceral adiposity in overweight or obese Latino and non-Latino adults.

Background/objectivesAlthough several studies have reported associations between moderate to vigorous physical activity (MVPA), body fatness and visceral adipose tissue (VAT), the extent to which associations differ among Latinos and non-Latinos remains unclear. This study evaluated the associations between body composition and MVPA in Latino and non-Latino adults.Subjects/methodsAn exploratory, cross-sectional analysis was conducted using baseline data collected from 298 overweight adults enrolled in a 12-month randomized controlled trial that tested the efficacy of text messaging to improve weight loss. MVPA, body fatness and VAT were assessed by waist-worn accelerometry, dual-energy x-ray absorptiometry (DXA), and DXA-derived software (GE CoreScan GE, Madison, WI, USA), respectively. Participants with <5 days of accelerometry data or missing DXA data were excluded; 236 participants had complete data. Multivariable linear regression assessed associations between body composition and MVPA per day, defined as time in MVPA, bouts of MVPA (time per bout ⩾10 min), non-bouts of MVPA (time per bout <10 min) and meeting the 150-min MVPA guideline. The modifying influence of ethnicity was modeled with a multiplicative interaction term.ResultsThe interaction between ethnicity and MVPA in predicting percent body fat was significant (P=0.01, 95% confidence interval (CI) (0.58, 4.43)) such that a given increase in MVPA was associated with a greater decline in total body fat in non-Latinos compared with Latinos (adjusted for age, sex and accelerometer wear time). There was no interaction between ethnicity and MVPA in predicting VAT (g) (P=0.78, 95% CI (-205.74, 273.17)) and body mass index (BMI) (P=0.18, 95% CI (-0.49, 2.26)).ConclusionsAn increase in MVPA was associated with a larger decrease in body fat, but neither BMI nor VAT, in non-Latinos compared with Latinos. This suggests that changes in VAT and BMI in response to MVPA may be less influenced by ethnicity than is total body fatness

The nature of solar brightness variations

The solar brightness varies on timescales from minutes to decades. Determining the sources of such variations, often referred to as solar noise, is of importance for multiple reasons: a) it is the background that limits the detection of solar oscillations, b) variability in solar brightness is one of the drivers of the Earth's climate system, c) it is a prototype of stellar variability which is an important limiting factor for the detection of extra-solar planets. Here we show that recent progress in simulations and observations of the Sun makes it finally possible to pinpoint the source of the solar noise. We utilise high-cadence observations from the Solar Dynamic Observatory and the SATIRE model to calculate the magnetically-driven variations of solar brightness. The brightness variations caused by the constantly evolving cellular granulation pattern on the solar surface are computed with the MURAM code. We find that surface magnetic field and granulation can together precisely explain solar noise on timescales from minutes to decades, i.e. ranging over more than six orders of magnitude in the period. This accounts for all timescales that have so far been resolved or covered by irradiance measurements. We demonstrate that no other sources of variability are required to explain the data. Recent measurements of Sun-like stars by CoRoT and Kepler uncovered brightness variations similar to that of the Sun but with much wider variety of patterns. Our finding that solar brightness variations can be replicated in detail with just two well-known sources will greatly simplify future modelling of existing CoRoT and Kepler as well as anticipated TESS and PLATO data.Comment: This is the submitted version of the paper published in Nature Astronom

RR Lyrae Stars In The GCVS Observed By The Qatar Exoplanet Survey

We used the light curve archive of the Qatar Exoplanet Survey (QES) to investigate the RR Lyrae variable stars listed in the General Catalogue of Variable Stars (GCVS). Of 588 variables studied, we reclassify 14 as eclipsing binaries, one as an RS Canum Venaticorum-type variable, one as an irregular variable, four as classical Cepheids, and one as a type II Cepheid, while also improving their periods. We also report new RR Lyrae sub-type classifications for 65 variables and improve on the GCVS period estimates for 135 RR Lyrae variables. There are seven double-mode RR Lyrae stars in the sample for which we measured their fundamental and first overtone periods. Finally, we detect the Blazhko effect in 38 of the RR Lyrae stars for the first time and we successfully measured the Blazhko period for 26 of them.Comment: Accepted IBV

Influence of Cytomatrix Proteins on Water and on Ions in Cells

This review concerns the influence that cytomatrix proteins have on the motional properties of water and on the major inorganic ions in cells. The techniques we used for study of water in cells and on the cytomatrix proteins include: pulsed NMR of water protons, quench cooled ice crystal imprint size, and osmotic behavior. The technique for study of ions involved use of electron-probe X-ray microanalysis of thin cryosections of cells. The cytomatrix was found to play the major role in determining the extent of hydration water in cells, The amount of hydration water varied greatly between cell types (e.g., lens fiber cells have no detectable bulk water) and varied in the same cell type studied under different states (e.g., unfertilized and fertilized sea urchin eggs). Aggregation of cytomatrix proteins (actin in particular) is a determinant of the extent of hydration water in cells. Hydration water appears not to participate in the ideal osmotic equation of van\u27t Hoff. The ionic content of cells does not accurately predict the chemical activity of the ions in cytoplasm. A major proportion of intracellular K+ and a substantial fraction of Cl- was found to be influenced by the cytomatrix such that their diffusion was impaired. The cytomatrix is responsible for the decreased motional properties of a substantial portion of cellular water and ions

Does increasing biodiversity in an urban woodland setting promote positive emotional responses in humans? A stress recovery experiment using 360-degree videos of an urban woodland

Green spaces can support human stress reduction and foster positive emotional well-being. Previous research has suggested that biodiversity (i.e. the variety of species of plants and animals in a given location) can enhance recovery from stress even further. However, there is limited experimental evidence testing this hypothesis and results, to date, have been mixed. This study aimed to provide further understanding of the role of biodiversity (actual or perceived) on human well-being by experimentally manipulating species richness and stress. Participants (372 in total) took part in an online experiment, where they received an episode of mild stress before watching a 360-degree video to recover. The video showed the same location, an urban woodland, but at one of four artificially manipulated levels of biodiversity. The participants reported their Positive and Negative Affect before and after the stress induction and after watching the video, providing a measure of their stress and well-being throughout the experiment. Participants also reported their perceptions of biodiversity (i.e. how diverse they thought the location was) and elaborated on their responses with brief comments. Repeated Measure Analysis of Variance revealed that exposure to all levels of biodiversity reduced the participants’ Negative Affect, but with no significant difference between the conditions. However, the analysis showed higher Positive Affect in those participants who perceived the environment as more biodiverse. Comments from participants indicated that those who reported noticing flowers and trees in the environment also showed higher Positive Affect. This suggests that perceiving biodiversity promotes more positive emotions, but critically one needs to actually notice (engage with) the components of biodiversity to elicit these extra benefits

Constraints on Adaptive Evolution: The functional trade-off between reproduction and fast-start swimming performance in the Trinidadian guppy (Poecilia reticulata)

The empirical study of natural selection reveals that adaptations often involve trade-offs between competing functions. Because natural selection acts on whole organisms rather than isolated traits, adaptive evolution may be constrained by the interaction between traits that are functionally integrated. Yet, few attempts have been made to characterize how and when such constraints are manifested or whether they limit the adaptive divergence of populations. Here we examine the consequences of adaptive life-history evolution on locomotor performance in the live-bearing guppy. In response to increased predation from piscivorous fish, Trinidadian guppies evolve an increased allocation of resources toward reproduction. These populations are also under strong selection for rapid fast-start swimming performance to evade predators. Because embryo development increases a female\u27s wet mass as she approaches parturition, an increased investment in reproductive allocation should impede fast-start performance. We find evidence for adaptive but constrained evolution of fast-start swimming performance in laboratory trials conducted on second-generation lab-reared fish. Female guppies from high-predation localities attain a faster acceleration and velocity and travel a greater distance during fast-start swimming trials. However, velocity and distance traveled decline more rapidly over the course of pregnancy in these same females, thus reducing the magnitude of divergence in swimming performance between high- and low-predation populations. This functional trade-off between reproduction and swimming performance reveals how different aspects of the phenotype are integrated and highlights the complexity of adaptation at the whole-organism level