64 research outputs found
Genome-Wide Association Analysis Identifies a Mutation in the Thiamine Transporter 2 (SLC19A3) Gene Associated with Alaskan Husky Encephalopathy
- Author
- A Cerase
- A Force
- Andrew W. Bollen
- Beverly K. Sturges
- BH Robinson
- BH Robinson
- Birgit Puschner
- Brian H. Robinson
- Cameron Ackerley
- Cecilia Giulivi
- CJ Abramson
- CL Matwichuk
- Danika L. Bannasch
- DH Read
- DM Glerum
- Emily A. Brown
- F Depeint
- F Depeint
- F Xu
- G. Diane Shelton
- Gerard Roel Rutteman
- Heather J. Huson
- J Finsterer
- JD Eudy
- Jessie M. Cameron
- JJ Wakshlag
- Jonathan A. Runstadler
- K Baiker
- K Yamada
- Karen M. Vernau
- MC Maj
- O Brenner
- Peter J. Dickinson
- PT Ozand
- R Debs
- RJ Steel
- RJ Toonen
- Robert J. Higgins
- S Kono
- S Purcell
- Salvatore DiMauro
- V Ganapathy
- VS Subramanian
- WQ Zeng
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/11/2012
- Field of study
Alaskan Husky Encephalopathy (AHE) has been previously proposed as a mitochondrial encephalopathy based on neuropathological similarities with human Leigh Syndrome (LS). We studied 11 Alaskan Husky dogs with AHE, but found no abnormalities in respiratory chain enzyme activities in muscle and liver, or mutations in mitochondrial or nuclear genes that cause LS in people. A genome wide association study was performed using eight of the affected dogs and 20 related but unaffected control AHs using the Illumina canine HD array. SLC19A3 was identified as a positional candidate gene. This gene controls the uptake of thiamine in the CNS via expression of the thiamine transporter protein THTR2. Dogs have two copies of this gene located within the candidate interval (SLC19A3.2 – 43.36–43.38 Mb and SLC19A3.1 – 43.411–43.419 Mb) on chromosome 25. Expression analysis in a normal dog revealed that one of the paralogs, SLC19A3.1, was expressed in the brain and spinal cord while the other was not. Subsequent exon sequencing of SLC19A3.1 revealed a 4bp insertion and SNP in the second exon that is predicted to result in a functional protein truncation of 279 amino acids (c.624 insTTGC, c.625 C>A). All dogs with AHE were homozygous for this mutation, 15/41 healthy AH control dogs were heterozygous carriers while 26/41 normal healthy AH dogs were wild type. Furthermore, this mutation was not detected in another 187 dogs of different breeds. These results suggest that this mutation in SLC19A3.1, encoding a thiamine transporter protein, plays a critical role in the pathogenesis of AHE.University of California, Davis. School of Veterinary Medicine. Center for Companion Animal Healt
Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration
- Author
- A Grimson
- A Kauffmann
- AJ Jacobs
- AJ Kole
- Alan R. Harvey
- AR Harvey
- AT McCurley
- BW Kusik
- C Gervasi
- C Vannahme
- CG Becker
- D Fischer
- DA Cameron
- Denise Anderson
- DM Garcia
- DP Bartel
- DW Thomson
- E Berezikov
- EJ Thatcher
- EJ Thatcher
- EV Edeleva
- F Elsaeidi
- F Taïbi
- GK Smyth
- H Chang
- I Ulitsky
- J Ganesalingam
- J Rodger
- J Rodger
- J Wang
- J Wlodarczyk
- J Xu
- J Zhong
- JA Kiernan
- Jennifer Rodger
- JF Diaz Quiroz
- JT Thomas
- K Matsumoto-Miyai
- K Rajaram
- Keith M. Giles
- Kim W. Carter
- KJ Livak
- KK-H Farh
- KL Wegener
- KS Kosik
- L Li
- L Wang
- LD Beazley
- LGW Hilgenberg
- LI Benowitz
- LP Lim
- M Agudo
- M Berkelaar
- M Hellstrom
- M Klemenčič
- M Yunta
- MB Veldman
- ME Ritchie
- ML Borowsky
- NJ Cairns
- P Bergman
- P Bono
- P Bono
- P He
- P Parikh
- Paula I. Fuller-Carter
- R Niwa
- R Ramachandran
- R Reif
- R Vuilleumier
- RA Irizarry
- RE Kesteren van
- RG Lafreniere
- RR Bernhardt
- RR Williams
- S Ackerley
- S Kato
- S Valastyan
- S Zou
- S-y Park
- SA Dunlop
- SA Lipton
- SG Jantzen
- SK Madathil
- T Becker
- T Sehm
- TP Gschwend
- TP Sharma
- VAO Silva
- XT Ge
- XY Lu
- Y Benjamini
- Y-m Yu
- YH Yang
- Z Wang
- Z Yang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- Abellán AN
- Abellán AN
- Abellán AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- Alcázar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- Alegría L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
- Andersson S
- Andoh K
- Andrade AH
- Andrade AH
- Andrade AH
- Andrade G
- Andreis DT
- Andreis DT
- Annane D
- Antonelli M
- Antoniadou A
- Antonio C
- Antonucci E
- Antón DG
- Anzueto A
- Appiani F
- Aquevedo A
- Aragon C
- Araujo NJ
- Araujo VF
- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
- Arias CC
- Arias N
- Arias-Verdu MD
- Arias-Verdu MD
- Arias-Verdu MD
- Armaganidis A
- Arora MK
- Arora N
- Arrigo M
- Arslantas MK
- Artiguenave M
- Aslanian P
- Aspide R
- Asyralyyeva G
- Ataman S
- Ataman S
- Atchade E
- Atchade E
- Atchasiri S
- Athapattu P
- Atkins G
- Aublanc M
- Aublanc M
- Augustin P
- Augustin P
- Auquier P
- Avilés-Jurado FX
- Avramidis V
- Ayala LY
- Aydin M
- Azevedo JC
- Azevedo JR
- Aznar GP
- Babalis D
- Babini G
- Bachli EB
- Bader A
- Bader A
- Baena J
- Baidya DK
- Baikova VN
- Bakker J
- Balcázar LC
- Balcázar LC
- Baldassarri R
- Baldwin CE
- Balik M
- Ball I
- Ballin A
- Balsera B
- Banderas-Bravo ME
- Banderas-Bravo ME
- Bandert A
- Bangstad IL
- Baptista N
- Baquero JD
- Barbadillo S
- Barberet G
- Barberet G
- Barberet G
- Barbier J
- Barcenilla F
- Barea-Mendoza JA
- Barinas OD
- Baron AV
- Barrachina LG
- Barral M
- Basile-Filho A
- Bassi GL
- Bates D
- Battistini M
- Bauer M
- Bauer PR
- Baumstarck K
- Baumstarck K
- Bawin M
- Bazan N
- Bañeras J
- Beane A
- Beduneau G
- Beduneau G
- Beduneau G
- Beeharry SD
- Beerepoot M
- Begzjav T
- Beishuizen A
- Bell C
- Belletti A
- Bellissimo-Rodrigues F
- Belloli A
- Bellomo R
- Bellver BQ
- Belmonte R
- Ben-Hamouda N
- Bendel S
- Bendel S
- Benyamina M
- Beretta S
- Berg R
- Bergantino B
- Berghmans J
- Bernal FF
- Berric A
- Berrutti D
- Berthelsen RE
- Bertini P
- Bertini P
- Berto MB
- Besevli SG
- Bestle MH
- Bettex D
- Bettex DA
- Beunders R
- Bhasin D
- Bhattal MK
- Bhide S
- Bianchi I
- Bianchi I
- Bianzina S
- Bianzina S
- Bianzina S
- Bishop J
- Bissenova N
- Bisso MC
- Blans MJ
- Blobner M
- Bloomer MJ
- Blot K
- Blot S
- Blot S
- Boa F
- Bobi Q
- Bodingbauer M
- Bodí M
- Boer C
- Bogossian E
- Bonet S
- Bonn M
- Bonnet M
- Borges FK
- Bouadma L
- Boucekine M
- Bougouin W
- Bourenne J
- Boyd JG
- Boyd JG
- Bozbay S
- Bozza F
- Bradac O
- Brandon RA
- Brandon RB
- Braschi A
- Braschi A
- Braschi A
- Brasseur A
- Brasseur A
- Brasseur A
- Braune S
- Brazzi L
- Breitkreutz R
- Brianti R
- Brioni M
- Brochard L
- Brochard L
- Brochard L
- Brock N
- Brody DL
- Brook R
- Brousseau C
- Brown K
- Brugger SC
- Brugger SC
- Bruno F
- Bruno K
- Brusasco C
- Brusasco C
- Brusasco C
- Bruyere O
- Bucknall T
- Buddi S
- Buise M
- Buitinck SH
- Buranavanich P
- Bureau C
- Burle JF
- Burtin P
- Busico M
- Butler MB
- Butrov AV
- Caballero CH
- Caballero J
- Cabello JT
- Cabello JT
- Cabrera AR
- Cabrera JL
- Cabrera JL
- Cabrini L
- Cairus C
- Cakin O
- Caliskan K
- Calpe P
- Calvo CP
- Calvo SA
- Camargo M
- Cambronero JA
- Cameron C
- Campbell R
- Campelo FA
- Campelo FA
- Campos LM
- Cannesson M
- CAPCRI Study
- Capellier G
- Carbonara M
- Cardellino S
- Cardenas CL
- Cariou A
- Cariou A
- Carlesso E
- Carmona AF
- Carmona SA
- Carmona SA
- Carmona SA
- Carmona SA
- Carone M
- Carpio D
- Carratalá A
- Carreira MM
- Carrero-Gómez F
- Carreño ER
- Carreño R
- Carvalho JP
- Carvalho KV
- Casals XN
- Casals XN
- Cassina T
- Castañeda DP
- Castellana D
- Castellanos A
- Castellanos A
- Castillo-Lorente E
- Castillo-Lorente E
- Catalan M
- Catalán RM
- Catena E
- Catena E
- Cauwenberghs H
- Cavalcanti D
- Cavalheiro AM
- Cavalier E
- Cavicchi FZ
- Cavicchi FZ
- Cengiz M
- Ceriani R
- Cermelli S
- Cerović O
- Cha YS
- Chabanne R
- Chacon-Alves S
- Champigneulle B
- Champigneulle B
- Chan KC
- Chan KK
- Chan WS
- Chang CH
- Chang WY
- Chao A
- Chao A
- Chao AS
- Chao HC
- Chaouat M
- Charitidou E
- Charpentier C
- Charpentier J
- Charron C
- Chatelon J
- Chaudhari HK
- Chaussard M
- Chavanon O
- Chaves S
- Chelly J
- Chemam S
- Chen CM
- Chen CM
- Chen CW
- Chen CW
- Chen GQ
- Chen L
- Chen YS
- Chen YS
- Chen YS
- Cheng CC
- Cheng CC
- Cheng CC
- Cheng CC
- Cheng KC
- Cheng YJ
- Chernyshuk S
- Chevret S
- Chhor V
- Chiang CC
- Chiang CH
- Chiang CH
- Chiang CH
- Chiappa C
- Chiou KR
- Chiou KR
- Chiou KR
- Chiu LC
- Chiumello D
- Chiurazzi C
- Chiurazzi C
- Cho Y
- Cho YJ
- Cho YJ
- Choi JY
- Choi JY
- Choi KS
- Choi S
- Choi YJ
- Choi YY
- Chok L
- Cholkraisuwat J
- Cholley B
- Chondropoulos S
- Chou W
- Chouris I
- Chouvarda I
- Christopher KB
- Chrétien JM
- Chrétien JM
- Chrétien JM
- Chumaev A
- Chung CR
- Churchill K
- Chytas A
- Cinel I
- Cinnella G
- Citerio G
- Citerio G
- Clavel M
- Clemente EA
- Clermont G
- Cleyet M
- Cohen Y
- Colaprico A
- Colino L
- Collange O
- Colombo A
- Colombo A
- Colson P
- Combes A
- Concha P
- Connolly B
- Constan A
- Constan A
- Constan A
- Conte V
- Conti G
- Conti G
- Contreras KM
- Contreras MR
- Cook DJ
- Coombs M
- Cordeiro CP
- Cordero M
- Cordolcini V
- Cordovilla-Guardia S
- Cordón J
- Corona A
- Corona A
- Corradi F
- Corradi F
- Corradi F
- Correa-Chamorro E
- Corte FD
- Cortes ML
- Corzo L
- Coss-Bu JA
- Coss-Bu JA
- Costa MI
- Costa RC
- Costa RC
- Costa RC
- Costanzo E
- Cotoia A
- Cottini SR
- Cottle D
- Cotton H
- Cotton H
- Courant P
- Cowan R
- Creagh-Brown B
- Cressoni M
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Creteur J
- Crimella F
- Cron N
- Cuellar AI
- Cui N
- Cunha MM
- Curiel-Balsera E
- Curiel-Balsera E
- Curinga M
- Curtis A
- Cuthbertson BH
- Cutuli SL
- Câmara M
- D'Arsigny C
- da Silva SL
- da Silva VZ
- Daga-Ruiz D
- Dalhuisen A
- Dalorzo M
- Damas P
- Dambrosio M
- Damås JK
- Das Neves A
- David H
- Davis C
- Davis P
- Day A
- de Abreu MG
- De Backer A
- De Brito-Ashurst I
- De Cassai A
- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
- De La Rica AS
- De la Torre MA
- De Maglie M
- De Maglie M
- de Molina FJ
- De Morton N
- de Oca Sandoval MA
- De Pascale G
- De Rosa S
- De Sanctis F
- De Silva AP
- De Sousa I
- de Vera AP
- de Wilde W
- De Zani D
- Deblier I
- DeBrunnar R
- Del Arco A
- Del Moral OL
- Del Olmo R
- Del Rosario CG
- Del Sorbo L
- Delgado CP
- Delgado MJ
- Delgado-Amaya M
- Demirkiran O
- Demoule A
- Denehy L
- Der Kinderen EP
- Descotte E
- Deshpande K
- Desmard M
- Desmard M
- Deveugele M
- Deye N
- Di Bello F
- Di Giancamillo M
- Di Gravio V
- Di Gregorio A
- Di Mussi R
- Di Rosso R
- Diaz DD
- Diaz P
- Dilek M
- Dilly MP
- Dima E
- Dimitroulakis K
- Dimitrov BD
- Dimitrov BD
- Dimopoulou IK
- Dinh A
- Divatia JV
- Dixon J
- Doganci M
- Doglia JA
- Doherty P
- Dolset RA
- Dominguez JP
- Domínguez JP
- Donald CL
- Donnino M
- Doorduin J
- Dorent R
- Dos Reis Miranda D
- Dos Santos HP
- Dougall PC
- Doyle J
- Doyle J
- Drover J
- Duarte R
- Dubois EA
- Dubrawski A
- Dubó S
- Dudas G
- Dudoignon E
- Dumas F
- Dunthorne E
- Duran N
- Durand M
- Durovray JD
- Durrant J
- Duzgun M
- Díaz E
- Díaz JJ
- Díaz M
- Díaz PV
- Dünser MW
- E Silva ZC
- E YY
- Ebeling G
- Echeverri JE
- Echeverría JG
- Ediboglu O
- Ediboglu O
- Egea-Guerero JJ
- Egginton JS
- Egi M
- El Adawy AS
- El Hamid MA
- El Hossainy R
- El Sayed E
- El Sayed F
- El Sayed I
- El-Hamamsy M
- El-Keraie A
- Eladawy S
- Elbers PW
- Elgendy M
- Eliet J
- Emmanuel J
- Emmerich M
- Encina B
- Endacott R
- Endacott R
- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
- Erdogan M
- Eroles AA
- Escalada SH
- Escalada SH
- Escoval A
- Escribá A
- Escórcio S
- Eslami S
- Espinasse F
- Espinel E
- Estagnasie P
- Esteban A
- Estella A
- Estenssoro E
- Evelein-Brugman S
- Facchin F
- Faivre V
- Fang M
- Fanzaghi P
- Farias P
- Faulds MC
- Fave G
- Feehan A
- Feijoo AM
- Feliot E
- Ferez MA
- Fernandes MJ
- Fernandes N
- Fernandez NG
- Fernandez R
- Fernandez-Zamora MD
- Fernández IF
- Fernández L
- Fernández MV
- Fernández PA
- Fernández-Barat L
- Fernández-Mondéjar E
- Fernández-Ortega JF
- Ferraz AB
- Ferrero-Calleja J
- Ferri F
- Ferry A
- Ferré A
- Ferrón FR
- Ferrón FR
- Fiks T
- Fiks T
- Fileković S
- Filho CA
- Filho CA
- Filho CA
- Filipe E
- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
- Fless K
- Floccard B
- Flowers E
- Follin A
- Follin A
- Fong KY
- Fontaiña LP
- Fontana V
- Fontenot T
- Forel JM
- Forni L
- Forni L
- Forni LG
- Forni LG
- Forni LG
- Fournel E
- Fox B
- Franchi P
- Francioni JE
- Francioni JE
- Franco JF
- Frantzeskaki F
- Frantzeskaki F
- Frat JP
- Frat JP
- Frat JP
- Freile MT
- Frenzel T
- Frigeni B
- Frithiof R
- Fritz C
- FROG ICU Investigators
- Fromentin M
- Frontera PR
- Fuentes M
- Fumagalli F
- Fumagalli F
- Fumis RR
- Fushimi K
- Gabán-Díez Á
- Gadgil S
- Gaide-Chevronnay L
- Gainnier M
- Gaite FB
- Gaizauskas E
- Gajic O
- Galache JA
- Gallego-Corpa AI
- Gameiro J
- Gancedo CH
- Gandini L
- Gando S
- Gando S
- Gando S
- Gando S
- Gandola A
- Gandolfi S
- Ganuza MS
- Garcia IP
- Garcia IP
- Garcia M
- Garcia PK
- Garcia-Alvarez JM
- Garcia-Alvarez JM
- Garcia-Delgado M
- Garcia-Gigorro R
- García MF
- García-Martínez MV
- García-Olivares P
- Garnacho-Montero J
- Garrido BB
- Garrido BB
- Garrido EM
- Garrouste M
- Gaspard N
- Gasparovic V
- Gattinoni L
- Gaudard P
- Gavranovic Z
- Gavrychenko D
- Gayat E
- Geantot MA
- Gemmell L
- Gemmell LK
- Genc D
- Genève C
- Georgopoulos D
- Geri G
- GETGAG Working Group
- GETGAG/SEMICYUC
- Ghabina S
- Ghazal S
- Gherli T
- Gherli T
- Ghosh S
- Giannantonio M
- Giannopoulos A
- Giesinger RE
- Gigorro RG
- Gil EM
- Gimenez J
- Gimillo MR
- Ginés AS
- Gioia A
- Girbes AR
- Girotto V
- Gkirkas K
- Glogoski MZ
- Gobert F
- Godinho I
- Godoy K
- Goldsworthy M
- Golovnya E
- Gomes AA
- Gomez C
- Gomez SE
- Gommers D
- Gommers D
- Gonzalez CA
- Gonzalez JA
- Gonzalez V
- Gonzalez-Engroba R
- González AS
- González BS
- González JC
- González-Jiménez AI
- Gonçalves B
- Goodwin S
- Gopcevic A
- Gordillo-Brenes A
- Gordo F
- Gordon M
- Gordon M
- Gorjup V
- Goto T
- Goto T
- Gottlieb J
- Gouveia J
- Gracia RM
- Gradišek P
- Granada RM
- Granados PR
- Grando M
- Granger CL
- Grangé S
- Grangé S
- Grangé S
- Granillo JF
- Grassi L
- Grasso S
- Greco E
- Green RS
- Greer M
- Gregory S
- Grelon F
- Grelon F
- Grelon F
- Grevelink M
- Grossestreuer A
- Guanziroli M
- Guarracino F
- Guarracino F
- Gubianas CM
- Guerrero AP
- Guerrero JE
- Guerrero-Lopez F
- Guerrero-López F
- Guervilly C
- Guidet B
- Guillamon LN
- Guillen JA
- Guillot M
- Guitard PG
- Guitard PG
- Guitard PG
- Gul F
- Gupta A
- Gupta D
- Gupta O
- Gustad LT
- Gutierrez LA
- Gutiérrez-Pizarraya A
- Guérin C
- Guérin C
- Guérin C
- Gálvez V
- Géri G
- Gómez LC
- Gómez-Jiménez C
- Gómez-Jiménez C
- Güven G
- Ha JK
- Hadley JS
- Haghbin S
- Haines R
- Hala P
- Hall D
- Hallows G
- Hallows G
- Hamilton A
- Han HS
- Han SH
- Han SH
- Handler E
- Hanekom S
- Haniffa R
- Hanna AA
- Haritydi T
- Harm S
- Harridge SD
- Harrison D
- Harrison M
- Hart N
- Hart R
- Hartmann J
- Hashimoto Y
- Hassanin H
- Hatakeyama J
- Hatib F
- Hawkins K
- Hayakawa M
- Hayakawa M
- Hayakawa M
- Hayakawa M
- Hayakawa M
- Hayashi K
- He X
- Healey AJ
- Hebert P
- Hegazy S
- Hellevuo H
- Helmy TA
- Helyar S
- Helyar S
- Hempel D
- Henderson MA
- Hendra H
- Henschel B
- Heras G
- Hernandis V
- Hernández A
- Hernández AA
- Hernández AA
- Hernández AA
- Hernández AA
- Hernández AA
- Hernández AA
- Hernández G
- Hernández-Tejedor A
- Herpain A
- Herrera AN
- Herrera AN
- Herrera AN
- Herrera AN
- Herrera AN
- Herrera AN
- Herruzo-Aviles A
- Heunks LM
- Hewitt H
- Heyne T
- Hickey S
- Hidalgo C
- Hikasa Y
- Hillier SD
- Himmel Y
- Himpe D
- Hinojosa-Perez R
- Hirata A
- Hirayama T
- Hirohata S
- Hodgson LE
- Hodgson LE
- Hofmeijer J
- Hollands S
- Hom H
- Hopkins PA
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- Hoppu S
- Hoppu S
- Horkan CM
- Horstmann C
- Horton A
- Horvat A
- Hou DS
- Houzé S
- Houzé S
- Howes D
- Hozhabri K
- Hrachovina M
- Hraiech S
- Hravnak M
- Hu HC
- Hua Y
- Hualde JB
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- Huang CH
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- Hubbard A
- Huber W
- Huddart S
- Hull AM
- Hung CY
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- Huot B
- Husheer SL
- Hutchings S
- Hutchison R
- Hwang GS
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- Ibañes PG
- Ibsen M
- Idei M
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- Idone FA
- Iesu E
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- Iglesias-Santiago A
- Ignacio ML
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- Itenov TS
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- Jacobs FM
- Jacques T
- Jaffal K
- Jamali S
- Jang BH
- Janotka M
- Janotka M
- Janotka M
- Jansen D
- Jansen N
- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
- Jardim JJ
- Jardim M
- Jareño A
- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
- Jeon YD
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- Jeong IY
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- Jimenez-Herrera MF
- Jiménez GJ
- Jo YH
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- Jochmans S
- John G
- Jonas M
- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
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- Juez A
- Juliarena A
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- Jung K
- Jung KW
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- Kaczirek K
- Kaese S
- Kalani N
- Kalenka A
- Kalfon P
- Kamali E
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- Kaneko M
- Kang M
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- Kang PL
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- Kara A
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- Karanjia N
- Karbing DS
- Karsten E
- Kasdan H
- Kashiya S
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- Katabami K
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- Katira BH
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- Kawamura N
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- Kay FU
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- Kayambu G
- Kazutoshi F
- Ke MW
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- Keep J
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- Keller E
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- Kerhuel L
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- Khadjibaev A
- Khaliq W
- Khine H
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- King HS
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- Kirakli C
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- Kirca H
- Kirman M
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- Kittnar O
- Klapsing P
- Klaus DA
- Kleinpell R
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- Ko JI
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- Kobayashi A
- Koco E
- Kodate A
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- Kokkini S
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- Komuro T
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- Kostalas M
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- Kovacikova L
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- Ku NS
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- Kubik M
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- Kurtz P
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- Kwon HM
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- Lacerda P
- Laerkner E
- Lafaurie M
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- Le Brocque R
- Lebherz-Eichinger D
- Lebiedz P
- Lebrón-Gallardo M
- Lebut J
- Lechner C
- Lee C
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- Lee DS
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- Legrand M
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- Legriel S
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- Letizia T
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- León JL
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- Lheureux O
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- Li R
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- Lipcsey M
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- Lissonde F
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- Lortat-Jacob B
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- Luna RR
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- Lusk J
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- Ly H
- Lázaro AS
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- Macfarlane B
- MacKay A
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- Mackey G
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- Maekawa K
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- Maertens B
- Maggiorini M
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- Magnanimi E
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- Mainardi JL
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- Maitra S
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- Malagurski B
- Malek F
- Malo LR
- Maly M
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- Manca T
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- Mancebo J
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- Mandal K
- Mantz J
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- Mar GY
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- Marca L
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- Mariotti L
- Marmanidou K
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- Marqués-Miñana MR
- Marra C
- Marrazzo F
- Marshall P
- Martin AD
- Martin AD
- Martin C
- Martin S
- Martin-Gallardo F
- Martin-Villen L
- Martin-Vivas A
- Martinez AD
- Martinez FH
- Martinez M
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- Martinez-Lopez P
- Martinez-Reyes L
- Martí AT
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- Martínez F
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- Mas A
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- Masjedi M
- Masjedi M
- Maslove D
- Masson S
- Masson S
- Masson S
- Mata PJ
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- Matamis D
- Matamis D
- Mateos HM
- Mates M
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- Matsuda Y
- Matsukubo S
- Mauri T
- Mayr U
- Mazo C
- Mazurenko G
- Mazza E
- McCormick B
- McCue C
- McHugh L
- Mckinlay J
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- McNelly AS
- McPhail MJ
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- Mebazaa A
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- Mecklenburg A
- Medar S
- Mehl A
- Meissonnier J
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- Mezidi M
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- Mimoun M
- Mimoz O
- Min A
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- Mingone D
- Mion MM
- Mira JP
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- Miranda F
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- Mirković T
- Mistry M
- Mistry N
- Mitchell M
- Mitchell S
- Mizobuchi S
- Mizugaki A
- Mizugaki A
- Mlcek M
- Moerer O
- Moffatt S
- Moggia F
- Mohamed AN
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- Mohankumar L
- Mojoli F
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- Moles SI
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- Monchi M
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- Montesinos-Cerro N
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- Moon YJ
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- Moore M
- Mora-Ordoñez J
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- Moreira T
- Morimatsu H
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- Morman D
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- Mourad M
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- Moxham J
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- Muncharaz AB
- Munteanu G
- Murakami H
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- Muscedere J
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- Mutlu H
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- Muñoz-Muñoz JL
- Márquez MP
- Mézière G
- Møller MH
- Na SJ
- Nadel S
- Nadkarni V
- Nagib H
- Naito T
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- Nakao A
- Nakataki E
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- Namiki M
- Namiki M
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- Naran P
- Nataf P
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- Ng L
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- Nieto B
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- Nouris C
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- Noč M
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- Nyunga M
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- Obukhova O
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- Ode S
- Oguzhan K
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- Okada Y
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- Payen D
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- Perez-Borrero L
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- Perinel S
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- Pienovi R
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- Pons S
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- Prabu N
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- Qiu H
- Quinart A
- Quintana S
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- Rabello L
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- Ramelli A
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- Ramos A
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- Ramírez CS
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- Ranse K
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- Rattray J
- Raurich JM
- Ravasi S
- Rawal J
- Ray B
- Ray BR
- Raymond T
- Recker F
- Recuerda M
- Redfors B
- Rees SE
- Reeves E
- Reginster JY
- Reichenspurner H
- Reinikainen M
- Reis A
- Reiter A
- Rello J
- Renault A
- Renes-Carreño E
- Renuka S
- Repessé X
- Resche-Rigon M
- Restrepo MI
- Reusch S
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- Revel N
- Revuelto-Rey J
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- Reyes LF
- Rezai F
- Riad Z
- Rialp G
- Richard C
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- Richard JC
- Richardson S
- Ricksten SE
- Rico J
- Rico T
- Ridi S
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- Rigal R
- Righy C
- Rigol M
- Rigon MR
- Rincon L
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- Riozzi P
- Riozzi P
- Ristagno G
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- Rivas RF
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- Riveiro M
- Rivera-Fernandez R
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- Rivera-Romero L
- Rizoli S
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- Roasio A
- Robaglia D
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- Rodrigues DP
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- Rodriguez A
- Rodriguez P
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- Rodriguez-Fernandez S
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- Roesthuis L
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- Rolin N
- Rolla F
- Rolland-Debord C
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- Routsi C
- Rouw N
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- Ruberto F
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- Sadamoto Y
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- Saeed S
- Saha T
- Saigal S
- Saito M
- Saito N
- Saitou N
- Sakai Y
- Sakieva FI
- Sakuma M
- Sakuraya M
- Sales G
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- Salluh J
- Sampath S
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- Sampley S
- Sampson D
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- Samy W
- Sanchez A
- Sanchez JA
- Sanchez-Orézzoli MG
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- Sato K
- Savi C
- Savin I
- Savvidou S
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- Sawamura A
- Scala S
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- Scanziani E
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- Schmidt M
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- Schröder T
- Schuepbach R
- Schultz MJ
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- Schwarz C
- Schwarze S
- Schwerdtfeger K
- Sciurti R
- Scott SH
- Sedlák P
- Seemann R
- Seet E
- Sekhri K
- Seldon T
- Sellés MD
- Sendid B
- Senussi T
- Serati Z
- Serbource-Goguel J
- Sergey S
- Serpytis M
- Serra J
- Sesana G
- Shah A
- Shah H
- Shawaf S
- Shears J
- Sheils MA
- Shekerdemian LS
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- Sherif H
- Shi ZH
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- Sibley S
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- Sidhu P
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- Silva G
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- Silva S
- Similowski T
- Simoes CM
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- Simsir M
- Simón IF
- Simón IF
- Simón JM
- Simón JM
- Singer L
- Singer M
- Singer M
- Singer M
- Singh H
- Singh N
- Sipylaite J
- Sirisena N
- Sirvent JM
- Siu K
- Sjövall F
- Skinner L
- Skrak P
- Skrifvars M
- Skrifvars MB
- Smekal D
- Snelson C
- Snyder AZ
- Sobhanian S
- Soeffker G
- Soilemezi E
- Soilemezi E
- Soilemezi E
- Sokolova E
- Solanki S
- Soler EA
- Solligård E
- Solé-Violán J
- Somhorst P
- Son Y
- Song I
- Song JG
- Song JG
- Song JW
- Song YG
- Song YG
- Sonneville R
- Sosa M
- Sossou A
- Sousa SC
- Soussi S
- Souza VA
- Spadaro S
- Spadaro S
- Spahn DR
- Spatenkova V
- Spazzadeschi A
- Spijkstra JJ
- Spronk PE
- Spronk PE
- Sprung CL
- St George’s University of London
- Stamm J
- Stamouli M
- Stanić R
- Starczewska M
- Staszewsky L
- Stauffert N
- Stella A
- Stephens T
- Stiphout C
- Stocchetti N
- Stocchetti N
- Stougianni M
- Street H
- Stretti F
- Struijs A
- Stubbs C
- Stubbs C
- Student Research Committee - Shiraz University of Medical Sciences
- Stümpfle R
- Stümpfle R
- Su F
- Su L
- Su PL
- Su PL
- Suchomel P
- Suh GJ
- Suh GJ
- Suh GJ
- Suh GY
- Suh JW
- Sullivan E
- Sun WZ
- Sun XM
- Sung D
- Suwanpasu S
- Suzuki S
- Suzuki T
- Swart M
- Sy O
- Sydow K
- Sylla P
- Sáez VC
- Sánchez B
- Sánchez B
- Sánchez EC
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez PC
- Sánchez PC
- Sánchez-Elvira LA
- Tabatabaei HR
- Tabei SH
- Taccone F
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taggu A
- Taggu A
- Takahashi H
- Takaki S
- Takaki S
- Takeda M
- Takeda M
- Takei T
- Takei T
- Talan L
- Tamura T
- Tanaka H
- Tanaka S
- Tanaka S
- Tane N
- Tang KB
- Tang LK
- Tapia A
- Tapponnier R
- Tapponnier R
- Tapponnier R
- Tarabrin O
- Tarabrin P
- Tavazzi G
- Tavazzi G
- Teboul JL
- Telli S
- Temprano-Gómez I
- Tena SA
- Tencé N
- Terzi N
- Terzi N
- Terzi N
- Terzi N
- Thabut G
- Thabut G
- Theodorakopoulou M
- Thies P
- Thilakasiri MC
- Thomas B
- Thompson E
- Thévenin D
- Tiainen M
- Timsit JF
- Tirkkonen J
- Tirumala S
- Tjepkema-Cloostermans MC
- Tobar M
- Tofiño AL
- Toh CH
- Tokyo Womens Medical University
- Tomas E
- Tomas E
- Tomic I
- Tominaga N
- Tomás MA
- Tonelotto BF
- Tonetti T
- Tonetti T
- Topcu L
- Tormos P
- Torner MM
- Torner MM
- Torrance HD
- Torrent RL
- Torrent RL
- Torres A
- Torres E
- Torres JC
- Torriglia F
- Torriglia F
- Torriglia F
- Torsvik M
- Tosi F
- Touratier S
- Touw HR
- Toval S
- Tran N
- Trapp O
- Travierso C
- Travieso PM
- Traynor T
- Trefler S
- Trenado J
- Trenado J
- Treso-Geira M
- Trifan B
- Triulzi F
- Troeltzsch M
- Troncoso I
- Trouiller P
- Tseng CJ
- Tsirigotis P
- Tsukahara K
- Tsunano Y
- Tsunoda M
- Tsunoda M
- Tsutui T
- Tucci MR
- Tudor BA
- Tuinman PR
- Tullo L
- Turel M
- Turon R
- Twisk JW
- Törnblom S
- Ugawa T
- Ujike Y
- Ulla DV
- Ullman A
- Unal M
- Urbanaviciute I
- Uriona S
- Urli T
- Usón MC
- Vaahersalo J
- Vaara S
- Vaid N
- Vakalos A
- Valbuena BL
- Valbuena BL
- Valeiras-Valero A
- Vallecoccia MS
- Vallejo-Báez J
- Vallverdu M
- Vallverdu M
- Vallverdú I
- Vallés J
- van den Boogaard M
- van der Heiden ES
- van der Hoeven JG
- van der Hoeven JG
- van der Voort PH
- van Galen T
- van Ieperen SN
- Van Logten T
- van Nes M
- van Putten MJ
- van Thiel RJ
- van Wijk A
- Vandijck D
- Vaneker I
- Vanhuyse F
- Vaporidi K
- Vaquerizo C
- Varas GM
- Varas JL
- Varea MM
- Vargiolu A
- Varma A
- Varpula T
- Vatsik MV
- Vazquez D
- Vedage D
- Vega LM
- Veigas P
- Vela JL
- Velasquez T
- Venkatesan K
- Venn R
- Venn R
- Venot M
- Venrdramin A
- Ventura-Rosado A
- Vergani G
- Verginella F
- Verhaeghe R
- Verhage R
- Vermeir P
- Veronesi M
- Vezzani A
- Vezzani A
- Vianna G
- Viciana R
- Vidal A
- Vidal MV
- Vidal MV
- Viegas E
- Vieillard-Baron A
- Vieira JE
- Viera MA
- Viera MA
- Vigne C
- Villa G
- Villa P
- Villalba D
- Villamizar PR
- Villamizar PR
- Villanova M
- Villard I
- Villarreal E
- Villarreal E
- Vincent B
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vinje LJ
- Vinsonneau C
- Vitaller S
- Vittone F
- Vogelaers D
- Voiriot G
- Volker T
- Volta CA
- Volta CA
- Vondrakova D
- Vondrakova D
- Vondrakova D
- Vong LV
- Vourli S
- Vrettou C
- Vucic M
- Vázquez CF
- Vázquez CF
- Wada T
- Wada T
- Wada T
- Wada T
- Waldauf P
- Wand S
- Wang CH
- Wang H
- Wann SR
- Wann SR
- Wann SR
- Wann SR
- Wathanawatthu T
- Wee S
- Welte T
- Welters I
- Wetz A
- Weyer CM
- White C
- Wiesner O
- Wijayatilake DS
- Wildenberg L
- Wilks M
- Wilson ME
- WIND study group
- WIND study group
- WIND study group
- Winder-Rhodes S
- Witter T
- Wolf M
- Wolff M
- Wong Y
- Wood B
- Wood CA
- Wood D
- Wood M
- Wray J
- Xie Z
- Xini A
- Xini A
- Xiol EA
- Xu M
- Yager T
- Yaguchi A
- Yaguchi A
- Yamaguchi O
- Yamaguchi O
- Yamaguchi Y
- Yamaguchi Y
- Yamamoto H
- Yamamoto N
- Yaman G
- Yamashita K
- Yamazaki A
- Yan WW
- Yan WW
- Yang JH
- Yang JS
- Yang YL
- Yasuda H
- Yatabe T
- Yebenes JC
- Yeh YC
- Yemets H
- Yergaliyeva A
- Yılmaz G
- Yilmazer F
- Yodice P
- Yokoyama M
- Yonis H
- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
- Zhang J
- Zhou JC
- Zhou JC
- Zhou JX
- Zhovnir V
- Zibandah N
- Zijlstra F
- Zimmerman J
- Zogheib E
- Zogheib E
- Zogheib E
- Zullino V
- Zwaag J
- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Correlative Light Microscopy is Required to Fully Comprehend Images of Cryofractured Surfaces of Complex Tissues in the Cryo FESEM
- Publication venue
- 'Cambridge University Press (CUP)'
- Publication date
- Field of study
673 Novel Role of the Insulin-Like Growth Factor-1 Receptor in Regulating Murine Intestinal Microvillus Structure and Fat Absorption
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Fatal hepatic failure and pontine and extrapontine myelinolysis in XMEA
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- Field of study
Lafora disease
- Author
- Publication venue
- 'John Libbey Eurotext'
- Publication date
- 01/01/2016
- Field of study
Lafora disease (LD) is an autosomal recessive progressive myoclonus epilepsy due to mutations in the EPM2A (laforin) and EPM2B (malin) genes, with no substantial genotype-phenotype differences between the two. Founder effects and recurrent mutations are common, and mostly isolated to specific ethnic groups and/or geographical locations. Pathologically, LD is characterized by distinctive polyglucosans, which are formations of abnormal glycogen. Polyglucosans, or Lafora bodies (LB) are typically found in the brain, periportal hepatocytes of the liver, skeletal and cardiac myocytes, and in the eccrine duct and apocrine myoepithelial cells of sweat glands. Mouse models of the disease and other naturally occurring animal models have similar pathology and phenotype. Hypotheses of LB formation remain controversial, with compelling evidence and caveats for each hypothesis. However, it is clear that the laforin and malin functions regulating glycogen structure are key. With the exception of a few missense mutations LD is clinically homogeneous, with onset in adolescence. Symptoms begin with seizures, and neurological decline follows soon after. The disease course is progressive and fatal, with death occurring within 10 years of onset. Antiepileptic drugs are mostly non-effective, with none having a major influence on the progression of cognitive and behavioral symptoms. Diagnosis and genetic counseling are important aspects of LD, and social support is essential in disease management. Future therapeutics for LD will revolve around the pathogenesics of the disease. Currently, efforts at identifying compounds or approaches to reduce brain glycogen synthesis appear to be highly promising
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