The Effect of Galactose on the Expression of Genes Regulated by Rrp6p

Gene expression is a multi-faceted phenomenon, governed not only by the sequence of nucleotides, but also by the extent to which a particular gene gets transcribed, how the transcript is processed, and whether or not the transcript ever makes it out of the nucleus. Rrp6p is a 5’-3’ exonuclease that can function independently and as part of the nuclear exosome in Saccharomyces cerevisiae (Portin, 2014). It degrades various types of aberrant RNA species including small nuclear RNAs, small nucleolar RNAs, telomerase RNA, unspliced RNAs, and RNAs that have not been properly packaged for export (Butler & Mitchell, 2010). This exosome mediated degradation is important as the accumulation of unprocessed mRNA transcripts can be harmful to the cell. These experiments sought to quantify changes in RNA levels in rrp6-Δ strains grown in glucose versus those grown in galactose compared to wild type strains grown in each of the carbon sources. The goal was to determine if there was an interplay between the genes regulated by Rrp6p and the genes involved in the switch from glucose metabolism to galactose metabolism. Based on the data, it appears that the absence of Rrp6p increases transcription in glucose while, in galactose, the absence of Rrp6p increases transcription to a significantly lesser degree than in glucose and in some cases decreases transcription

Developmental Functioning of Infants and Toddlers with Neurodevelopmental Disorders

Autism spectrum disorder (ASD), epilepsy, and cerebral palsy (CP) are some of the most common neurodevelopmental disorders among children with prevalence rates of 1.85% (Maenner et al., 2020), 1.2% (Zack & Kobau, 2017), and between 0.21 and 0.31% (Christensen et al., 2013), respectively. These neurodevelopmental disorders are highly comorbid with each other and with other disorders, such as intellectual disability (ID). While previous research has investigated developmental functioning in these neurodevelopmental disorders, it has primarily focused on only two at a time and in older children or adults. The current study aimed to investigate developmental functioning in these neurodevelopmental disorders and an atypical control group using the Battelle Developmental Inventory, Second Edition (BDI-2). The current sample included four groups (i.e., ASD, seizures, CP, atypical control), with 253 infants and toddlers in each. The results indicated significant differences in overall developmental functioning, in addition to individual subdomains of the BDI-2. These findings provide the basis for further research to investigate comorbidities of the three neurodevelopmental disorders and parse out the impact of ID

The right attitude: gender, conservatism, and career choice

Despite reductions in overt sexism and structural barriers to the advancement of women in the workforce, differences in the representation of women and men in various careers remain. Specifically, women tend to be overrepresented in traditionally feminine careers, which also tend to be lower in prestige and pay. The present study explored potential gender-related barriers to women\u27s advancement through examination of the perceptions of the femininity and masculinity of the RIASEC types (Holland, 1959; 1997). Specifically, the study sought to determine the role that the gender of the person portrayed in a career plays in the perceptions of the RIASEC types, as well as the contribution of the covariates right-wing authoritarianism, religious fundamentalism, and attitudes toward women. Participants were 334 university students who completed questionnaires and a card sort in which they sorted adjectives from the Bem Sex Role Inventory (Bem, 1981) to job descriptions representative of the RIASEC types. MANOVA and MANCOVA were used and gender and condition were found to have significant effects on the perceptions of the RIASEC types, while no significant covariates emerged. Implications of these results are discussed, including the fact that perceptions of the RIASEC types may be somewhat influenced by the gender of the person seen in the representative career

The Positive and Negative Valence of Gender in Traditional and Non-Traditional Career Choices

Women and men tend to be differentially represented in many careers, in spite of reductions in structural barriers to the advancement of women and in overt sexism. Women are often overrepresented in traditionally feminine careers. Careers populated mainly by women also tend to be lower in pay and prestige. The present study continued an exploration of various gender-related barriers to more equal representation of women and men in careers. Specifically, perceptions of the femininity and masculinity of the RIASEC types (Holland, 1959; 1997) and positive/negative ratings of the RIASEC types were examined. In addition, covariates representing sexism and conservatism (right-wing authoritarianism and religious fundamentalism) were included to determine their impact. Participants were 509 university students who completed questionnaires and a sorting activity in which they assigned feminine and masculine traits from the Bem Sex Role Inventory (Bem, 1981), the Personal Attributes Questionnaire (Spence & Helmreich, 1978), and the Positive-Negative Sex Role Inventory (Berger & KrahÃÂé, 2013) to occupational descriptions representing the RIASEC types. Participants also rated their attitudes to traits assigned to descriptions. MANOVA and MANCOVA were used and gender and condition were found to have significant effects on the perceptions of the RIASEC types, while only gender was found to have a significant effect on positive/negative ratings of the RIASEC types. The sexism and conservatism covariates were found to have significant effects with both perceptions of and attitudes toward the RIASEC types. These results are discussed in light of other research and implications for further research and career counseling

The Sound of Silence: Translating the Auditory Landscape of the North

In Quebec literature, the North has often been portrayed as a mythical, sacred, and elusive territory. Recent studies have suggested that literary representations of the North are not simply descriptions of a geographic location, but imagined spaces coloured by aesthetic, political, and ideological values. The present thesis examines my translation of twelve poems by three contemporary francophone authors from Quebec whose work explores the landscape of northern Quebec: Jean Morisset, Maude Smith Gagnon, and Natasha Kanapé Fontaine. In light of contemporary literary and multidisciplinary studies on the North, I will consider the difficulties encountered during translation. In particular, I will focus on how poetic representations of northern Quebec are problematic for writers and translators because poetry is fundamentally auditory, and the northern landscape is primarily associated with silence. Furthermore, I will discuss how the North is an imagined space that varies according to the authors’ culture, gender, and individual experiences. Drawing from research on the poetics of translation, I will strive to preserve each author’s auditory landscape, and thus maintain their varying and distinct perceptions of sound and silence in northern Quebec

Examining the Relationship between Parental Educational Expectations and a Community-Based Children’s Savings Account Program

Children’s Savings Account (CSA) program and parents’ educational expectations for their children. We examine survey data collected as part of the rollout and implementation of The Promise Indiana CSA program. Although results differ by parental income and education, results using the full sample suggest that parents are more likely to expect their elementary school-age children to attend college if they have a 529 account or were exposed to the additional aspects of the Promise Indiana program (i.e., the marketing campaign, college and career classroom activities, information about engaging champions, trip to a University, and the opportunity to enroll into The Promise). Parents who were both exposed to the additional aspects of the Promise Indiana program and have a 529 account are over three times more likely to expect their child to attend college than others, increasing to 13 times more likely among parents with no college education. Overall, results suggest a community-based CSA program – Promise Indiana – is associated with nontrivial benefits for families

Using Partnership and Prioritization to Achieve Whole Watershed Restoration in the Pacific Northwest

The goal of the Whole Watershed Restoration Initiative (WWRI) is to restore natural functions of whole watersheds in Oregon, Washington, and Idaho, while amplifying community-based partnerships focused on the strategic restoration of Pacific salmon and steelhead ecosystems. The WWRI partners (Ecotrust, NOAA Restoration Center, the U.S. Forest Service's Pacific Northwest Region, and Oregon Watershed Enhancement Board) are shifting the project selection and funding paradigm within our region from opportunistic to strategic by identifying "priority basins" and "focus watersheds" that represent shared regional priorities. Partnership funds are targeted to these areas in order to produce meaningful, measurable progress toward whole watershed restoration and salmon recovery. The collaborative identification of priorities is based on the convergence of several prioritization approaches: 1) Ecotrust's Conservation Opportunity Area modeling tool; 2) the Forest Service's Aquatic Restoration Strategies; and 3) NOAA-approved salmon recovery plans. Overlain together this prioritization approach identified 9 priority basins containing 28 focus watersheds throughout Oregon, Washington and Idaho. In the past 3 years the WWRI has provided over $5 million to 80 salmon and watershed restoration projects in the area. The proposed poster will focus on the technical framework for identifying priority basins and focus watersheds, and on the partnership's approach to measuring progress toward completion of major restoration priorities on a watershed scale.Presented at The Oregon Water Conference, May 24-25, 2011, Corvallis, OR

Association Between Sensation-Seeking Behaviors and Concussion-Related Knowledge, Attitudes, Perceived Norms, and Care-Seeking Behaviors among Collegiate Student-Athletes

There are limited data connecting personality and behavioral tendencies and traits related to concussion care-seeking/disclosure behaviors and minimal research exists surrounding the relationship between risky behaviors, sensation-seeking, and concussion-related outcomes. This study examined the association between sensation-seeking and a student-athlete’s concussion-related knowledge, attitudes, perceived social norms, and concussion care-seeking/disclosure behaviors (intention to disclose concussion symptoms, perceived control over symptom disclosure, self-removal from play due to concussion symptoms, continued play with concussion symptoms, and disclosure of all concussions at the time of injury). The current study utilized a retrospective cohort of collegiate student-athletes at a single National Collegiate Athletic Association Division I institution. Separate multivariable linear regression models estimating mean differences (MD) and 95% Confidence Intervals (CI) estimated the association between sensation-seeking and concussion knowledge, concussion attitudes, and perceived social norms. Separate multivariable binomial regression models estimating adjusted prevalence ratios (PR) and 95%CI estimated the association between sensation-seeking and intention to disclose concussion symptoms, perceived control over symptom disclosure, self-removal from play due to concussion symptoms, continued play with concussion symptoms, and disclosure of all concussions at the time of injury. All models were adjusted for sex, sport participation, and concussion history. Higher sensation-seeking was significantly associated with less favorable concussion attitudes (adjusted MD = -1.93; 95%CI = -3.04,-0.83), less favorable perceived social norms surrounding concussion (adjusted MD = -1.39; 95%CI = -2.06,-0.72), and continuing to play while experiencing concussion symptoms (adjusted PR = 1.50; 95%CI = 1.10, 2.06). Student-athletes with increased sensation-seeking could be at risk for failing to disclose a concussion, decreasing athlete safety and resulting in less optimal care post-injury. Results will inform future theory-based concussion education programs which consider behavioral tendencies and traits as well as sport culture to promote concussion care-seeking/disclosure and individualized interventions based on risky behavior engagement

The Grizzly, January 27, 2011

Bonner Leaders Host Hunger Banquet • UC Alumnus Discusses Alternative Careers in Science • Students Find Internships While Studying Abroad • Berman Museum Opens Two New Exhibitions • MLK Celebrations • Student Experiences Australian Flood • Students Travel to Spain for New Experiences • Internship Profile: Ananda Holton • Diversity Through Monologues • Opinion: Scheduling Classes is Too Difficult; Tragedy in Arizona: The Work of a Madman; Snapshots of London From my Time Studying Abroad • Swimming Training Trip to Florida Proves Rewardinghttps://digitalcommons.ursinus.edu/grizzlynews/1827/thumbnail.jp

The Grizzly, September 27, 2007

Going Green: Ursinus Commits to Improving Energy Efficiency • Ursinus Joins Fight Against U.K. Boycott • Grad School Guru Advises UC Seniors • Popping the Pill Continued: DRSP • Hillel and Muslim Student Association Host Break-Fast • Faculty Spotlight: Barbara von Schlegell • Book Review: Vain Art of the Fugue by Dumitru Tsepeneag • Opinions: Ursinus Goes (Not So) Silent for Jena 6; The Arctic Isn\u27t as Neutral Anymore • Superstitions • UC Hosting \u2707 Field Hockey NCAA Championship • Welcome to the Family: UCXChttps://digitalcommons.ursinus.edu/grizzlynews/1744/thumbnail.jp