139 research outputs found
Acciones Estratégicas para reducir los efectos de las Presiones Ambientales que influyen en el redimiento deportivo de Judocas (Original)
Recent data has shown that even in Olympic Games the athlete can lose a medal, a positive result due to the effects exerted by environmental pressures. The objective of this research is to propose a group of strategic actions to diminish the effects of environmental pressures in a judo team in Pinar del Río, Cuba. In order to carry out this study, a documentary review, a survey to athletes and an interview to Judo coaches were applied. It was demonstrated that all the pressures proposed in the study have a relative incidence in the state of opinion of the athletes, but it is the public pressure that most concerns the athletes. As a product of contribution to the solution of the scientific problem, a group of strategic actions is proposed that are directed to treat the pressures that most affect the athletes under study and also to foresee some consequences that could be caused by a deficient treatment of other environmental pressures.En datos recientes se ha demostrado que hasta en juegos olímpicos el atleta puede perder una medalla, un resultado positivo debido a los efectos que ejercen las presiones ambientales. Esta investigación tiene como objetivo: proponer un grupo de acciones estratégicas para disminuir los efectos de las presiones ambientales en un equipo de judocas de Pinar del Río, Cuba. Para realizar este estudio se aplicó una revisión documental, una encuesta a atletas y una entrevista a entrenadores de Judo. Se demostró que todas las presiones propuestas en el estudio tienenrelativa incidencia en el estado de opinión de los atletas pero es la presión de público la que más preocupa por parte de las atletas. Como producto de contribución a la solución del problema científico se propone un grupo de acciones estratégicas que se dirigen a tratar las presiones que más afectan a los atletas en estudio y también a preveeralgunos consecuencias que podrían causar un deficiente tratamiento de otras presiones ambientales
Diagnostico, manejo y seguimiento de infecciones vaginales en embarazadas de 18 a 30 años de edad, que consultan en la Unidad Comunitaria de Salud Familiar Unicentro Soyapango durante el periodo de Julio a Diciembre del 2018
La presente investigación se realizó para determinar el cumplimiento de la norma clínicas de ginecología y obstetricia, en lo referente a: diagnóstico, tratamiento, seguimiento, referencia oportuna y prevención de las infecciones de vaginitis en el embarazo, en mujeres de 18 a 30 años, que asistieron a controles prenatales básicos y consultas generales en la UCSF-E UNICENTRO; ya que por su alta incidencia de consultas de las embarazadas por vaginitis, es un problema que los profesionales de la salud debieron tratar de controlar y promover, si las pacientes consultaron por esta enfermedad que aumentó el riesgo de complicaciones fetales e incluso el aborto porque no consultaron a tiempo.
Fue mediante un análisis retrospectivo no experimental, se evaluaron las capacidades del médico y revisión documental de expedientes de 50 casos de infecciones por vaginitis en el embarazo que consultaron en el período de julio a diciembre de 2018. Se utilizó un instrumento de vaciado de expedientes para evaluar el conocimiento general de médicos en aspectos teóricos específicos de los lineamientos y tratamiento de infecciones de vaginitis en el embarazo, evidenciando que el profesional cumple con la norma
Road traffic safety, a challenge to public health in the XXI century Colombia
ABSTRACT: To review the topic regarding road traffic safety as a
challenge to public health in orderto define an intervention and
a research framework in the country. Methodology: national
and international data was traced back in yearbooks, printed
and electronic means, and SciELO\saludpública electronic
library. Results: development, extend, and tendencies of the
problem, as well as its constitutional, legal and pragmatic
framework in Colombia were systematized. Conclusions: the
relevance to carry out a systematic research procedure and
intervention of the problem in the xxi century Colombia was
made evident.RESUMEN: Revisar el tema seguridad-accidentalidad vial,
planteado como un desafío para la salud pública en el país,
definiendo un marco para su investigación e intervención.
Metodología: se buscó información nacional e internacional
del tema en anuarios, medios físicos, magnéticos y en la
biblioteca electrónica SciELO/saludpública. Resultados: se
sistematizaron aspectos de evolución, magnitud y tendencias
globales, así como del marco constitucional, legal y programáticodelproblema
enColombia.Conclusiones:seevidenció
la pertinencia de procesos sistemáticos de su investigación
e intervención en la Colombia delsiglo xxi
Factors associated with perception and expectations to work in the area of primary health care at five facilities of the first level care in Lima, Peru
Aim: To identify the frequency of perception and expectations to work in the area of primary health care(PHC) as well as theirassociated factors with personnel at five health facilities.
Method: Cross-sectional study on five health facilities of PHC. Perception and expectations to work in PHC were measured, and their association with social-work variables was investigated. Simple and multiple regression analysis was performed to estimate prevalence ratios (PR), using the Poisson family, robust variance and having a health facility as a cluster.
Results: Out of 94 participants, 64.9% did not have an adequate perceptionabout working in the area of PHC. The 60.6% had an expectation to work in PHC 10 years from now. A positive association was found between female gender and perception about working in the area of PHC (PR = 3.24). There was a negative association between being divorced and/or widowed and the expectation to work in PHC (PR: 0.51).
Conclusions: Perception about working in PHC is low, but more than half of the sample expect to work in PHC10 years from now. Being a woman increases the prevalence job perception in PHC. Working time over 5 years was positively associated with having expectations to work in PHC. On the contrary, divorced/widowed marital status was negatively associated
Activation of the Wnt/β-Catenin Signaling Pathway by Mechanical Ventilation Is Associated with Ventilator-Induced Pulmonary Fibrosis in Healthy Lungs
BACKGROUND: Mechanical ventilation (MV) with high tidal volumes (V(T)) can cause or aggravate lung damage, so-called ventilator induced lung injury (VILI). The relationship between specific mechanical events in the lung and the cellular responses that result in VILI remains incomplete. Since activation of Wnt/β-catenin signaling has been suggested to be central to mechanisms of lung healing and fibrosis, we hypothesized that the Wnt/β-catenin signaling plays a role during VILI. METHODOLOGY/PRINCIPAL FINDINGS: Prospective, randomized, controlled animal study using adult, healthy, male Sprague-Dawley rats. Animals (n = 6/group) were randomized to spontaneous breathing or two strategies of MV for 4 hours: low tidal volume (V(T)) (6 mL/kg) or high V(T) (20 mL/kg). Histological evaluation of lung tissue, measurements of WNT5A, total β-catenin, non-phospho (Ser33/37/Thr41) β-catenin, matrix metalloproteinase-7 (MMP-7), cyclin D1, vascular endothelial growth factor (VEGF), and axis inhibition protein 2 (AXIN2) protein levels by Western blot, and WNT5A, non-phospho (Ser33/37/Thr41) β-catenin, MMP-7, and AXIN2 immunohistochemical localization in the lungs were analyzed. High-V(T) MV caused lung inflammation and perivascular edema with cellular infiltrates and collagen deposition. Protein levels of WNT5A, non-phospho (Ser33/37/Thr41) β-catenin, MMP-7, cyclin D1, VEGF, and AXIN2 in the lungs were increased in all ventilated animals although high-V(T) MV was associated with significantly higher levels of WNT5A, non-phospho (Ser33/37/Thr41) β-catenin, MMP-7, cyclin D1, VEGF, and AXIN2 levels. CONCLUSIONS/SIGNIFICANCE: Our findings demonstrate that the Wnt/β-catenin signaling pathway is modulated very early by MV in lungs without preexistent lung disease, suggesting that activation of this pathway could play an important role in both VILI and lung repair. Modulation of this pathway might represent a therapeutic option for prevention and/or management of VILI
Recommended from our members
Soluble platelet-endothelial cell adhesion molecule-1, a biomarker of ventilator-induced lung injury
Introduction: Endothelial cell injury is an important component of acute lung injury. Platelet-endothelial cell adhesion molecule-1 (PECAM1) is a transmembrane protein that connects endothelial cells to one another and can be detected as a soluble, truncated protein (sPECAM1) in serum. We hypothesized that injurious mechanical ventilation (MV) leads to shedding of PECAM1 from lung endothelial cells resulting in increasing sPECAM1 levels in the systemic circulation. Methods: We studied 36 Sprague–Dawley rats in two prospective, randomized, controlled studies (healthy and septic) using established animal models of ventilator-induced lung injury. Animals (n = 6 in each group) were randomized to spontaneous breathing or two MV strategies: low tidal volume (VT) (6 ml/kg) and high-VT (20 ml/kg) on 2 cmH2O of positive end-expiratory pressure (PEEP). In low-VT septic animals, 10 cmH2O of PEEP was applied. We performed pulmonary histological and physiological evaluation and measured lung PECAM1 protein content and serum sPECAM1 levels after four hours ventilation period. Results: High-VT MV caused severe lung injury in healthy and septic animals, and decreased lung PECAM1 protein content (P < 0.001). Animals on high-VT had a four- to six-fold increase of mean sPECAM1 serum levels than the unventilated counterpart (35.4 ± 10.4 versus 5.6 ± 1.7 ng/ml in healthy rats; 156.8 ± 47.6 versus 35.6 ± 12.6 ng/ml in septic rats) (P < 0.0001). Low-VT MV prevented these changes. Levels of sPECAM1 in healthy animals on high-VT MV paralleled the sPECAM1 levels of non-ventilated septic animals. Conclusions: Our findings suggest that circulating sPECAM1 may represent a promising biomarker for the detection and monitoring of ventilator-induced lung injury
Metabolic engineering for improving anthranilate synthesis from glucose in Escherichia coli
© 2009 Balderas-Hernández et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens
La Educación Superior en Cuba: Un espacio de inclusión mediante las políticas públicas
La Educación Superior forma parte de las conquistas sociales que ha mantenido durante más de 50 años la revolución cubana. Constituye una de las obras más humanas y solidarias que se haya desarrollado en el mundo. Su inversión es importante para acometer el desarrollo económico-social de la nación, la cual se encuentra en el proceso de construcción socialista y, en las condiciones actuales, rediseña su modelo económico social. Desde la Economía Política como ciencia, es importante percibir a la Educación Superior, como una forma de distribución social. Carlos Marx en su estudio acerca de la reproducción, y los destinos de la riqueza creada a escala social, tuvo en cuenta que se instrumentaría, independientemente del aporte de cada cual, a la sociedad, sino que formaba parte según, el, de la satisfacción de necesidades colectivas. Sin embargo, la Educación Superior, dentro de los otros niveles educacionales, tiene sus peculiaridades y aunque en Cuba, todos por derecho que otorga la Constitución de la República podemos acceder a estos servicios, tiene un carácter elitista. Muchos factores inciden en ello forman parte de este análisis. Se trata entonces ante las nuevas condiciones de: Proponer vías que redunden en el perfeccionamiento de la Educación Superior, promuevan el acceso e inclusión mediante las políticas públicas. Se trata de lograr un mayor acceso a esta forma de enseñanza, sobre todo, tomando en cuenta que, en las condiciones actuales, la brecha en las desigualdades sociales, se amplían
Recommended from our members
Carbothermal reduction of mill scales formed on steel billets during continuous casting
AbstractA billet is a bar made from crude steel which surface contains scales which are rich in iron oxides. This study presents the carbothermal reduction of the scales formed in steel billets. The process included the reaction of the iron oxides contents with carbon (in ratio 5:1) and annealing in a tubular furnace under argon atmosphere. The occurred reactions are discussed using thermodynamic calculations and thermal analysis which indicate a three-stage reduction process Fe3O4 ➔ FeO ➔ Fe3C ➔α-Fe with intermediate reactions at the interval temperature 960 and 1300 °C. The X-ray diffraction confirms the reduction to α-Fe with minor presence of unreacted C, magnetite and wustite. Mössbauer spectroscopy analysis was performed at room temperature where a typical sextet corresponding to the dominant α-Fe is shown as well as wustite, magnetite and cementite to a lesser extent. The magnetization measurements confirm the ferromagnetic state corresponding to the α-Fe.</jats:p
Policondritis recidivante. Informe de un caso
La policondritis recidivante es una afección sistémica crónica y recidivante que afecta preferencialmente el tejido cartilaginoso de diversos órganos y sistemas produciendo una condromalacia con efectos adversos de los órganos comprometidos. El cuadro clínico compromete generalmente los cartílagos de las orejas y el globo ocular, con tumefacción y dolor, subsecuentemente se tornan blandos. Con frecuencia se compromete el septum nasal, ocasionando diversos grados de deformidad. Se presenta una paciente de 47 años, sexo femenino, piel blanca, procedencia rural, con antecedentes de Hipertensión Arterial bien tratada hace 27 años, que acude por presentar un dolor y sensación quemante en el pabellón auricular derecho.ABSTRACTRelapsing polychondritis is a systemic chronic relapsing condition and that preferentially affects the cartilage tissue of various organs and systems producing chondromalacia with adverse effects on the organs involved. The clinical picture usually involves the cartilage of the ears and the eyeball, with swelling and pain subsequently turn soft. Often the nasal septum is compromised, causing varying degrees of deformity. A 47 year old female, white skin, rural origin, with a history of well treated Hypertension 27 years ago, who came to present pain and burning sensation in the right ear
- …