Privacy-preserving edit distance computation using secret-sharing two-party computation

The edit distance is a metric widely used in genomics to measure the similarity of two DNA chains. Motivated by privacy concerns, we propose a 2PC protocol to compute the edit distance while preserving the privacy of the inputs. Since the edit distance algorithm can be expressed as a mixed-circuit computation, our approach uses protocols based on secret-sharing schemes like Tinier and SPD$\mathbb{Z}_{2^k}$; and also daBits to perform domain conversion and edaBits to perform arithmetic comparisons. We modify the Wagner-Fischer edit distance algorithm, aiming at reducing the number of rounds of the protocol, and achieve a flexible protocol with a trade-off between rounds and multiplications. We implement our proposal in the MP-SPDZ framework, and our experiments show that it reduces the execution time respectively by 81\% and 54\% for passive and active security with respect to a baseline implementation in a LAN. The experiments also show that our protocol reduces traffic by two orders of magnitude compared to a BMR-MASCOT implementation

ANÁLISIS GEOPOLÍTICO DE NEGOCIACIÓN DE SANTANDER CON TAILANDIA, MALASIA Y SINGAPUR (Geopolitical Negotiation Analysis of Santander with Thailand, Malaysia and Singapore)

En el siguiente trabajo se realizó un análisis de los factores de poder geopolítico, para identificar las oportunidades de negociación de Santander con los países de Tailandia, Malasia y Singapur. Se identificó que el Departamento de Santander es una región con un gran potencial para entrar al mercado del sudeste asiático, por lo tanto, es fundamental potencializar las oportunidades de negociación de Santander con estos tres países. Para la recolección de la información del trabajo se hizo a partir de análisis comparativos, considerando los factores sociales, económicos, políticos y culturales, determinando que Santander es una región con una oferta exportable diversificada y amplia, la cual puede ser recibida por los mercados de Tailandia, Malasia y Singapur

Hurricane Flood Hazard Assessment for the Archipelago of San Andres, Providencia and Santa Catalina, Colombia

Despite the low occurrence of tropical cyclones at the archipelago of San Andres, Providencia, and Santa Catalina (Colombia), Hurricane Iota in 2020 made evident the area vulnerability to tropical cyclones as major hazards by obliterating 56.4 % of housing, partially destroying the remaining houses in Providencia. We investigated the hurricane storm surge inundation in the archipelago by forcing hydrodynamic models with synthetic tropical cyclones and hypothetical hurricanes. The storm surge from synthetic events allowed identifying the strongest surges using the probability distribution, enabling the generation of hurricane storm surge flood maps for 100 and 500 year return periods. This analysis suggested that the east of San Andres and Providencia are the more likely areas to be flooded from hurricanes storm surges. The hypothetical events were used to force the hydrodynamic model to create worst-case flood scenario maps, useful for contingency and development planning. Additionally, Hurricane Iota flood levels were calculated using 2D and 1D models. The 2D model included storm surge (SS), SS with astronomical tides (AT), and SS with AT and wave setup (WS), resulting in a total flooded area (percentage related to Providencia's total area) of 67.05 ha (3.25 %), 65.23 ha (3.16 %), and 76.68 ha (3.68%), respectively. While Hurricane Iota occurred during low tide, the WS contributed 14.93 % (11.45 ha) of the total flooded area in Providencia. The 1D approximation showed that during the storm peak in the eastern of the island, the contribution of AT, SS, and wave runup to the maximum sea water level was -3.01%, 46.36%, and 56.55 %, respectively. This finding provides evidence of the water level underestimation in insular environments when modeling SS without wave contributions. The maximum SS derived from Iota was 1.25 m at the east of Providencia, which according to this study has an associated return period of 3,234 years. The methodology proposed in this study can be applied to other coastal zones and may include the effect of climate change on hurricane storm surges and sea-level rise. Results from this study are useful for emergency managers, government, coastal communities, and policymakers as civil protection measures

The 3-3-1 model with S_4 flavor symmetry

We construct a 3-3-1 model based on family symmetry S_4 responsible for the neutrino and quark masses. The tribimaximal neutrino mixing and the diagonal quark mixing have been obtained. The new lepton charge \mathcal{L} related to the ordinary lepton charge L and a SU(3) charge by L=2/\sqrt{3} T_8+\mathcal{L} and the lepton parity P_l=(-)^L known as a residual symmetry of L have been introduced which provide insights in this kind of model. The expected vacuum alignments resulting in potential minimization can origin from appropriate violation terms of S_4 and \mathcal{L}. The smallness of seesaw contributions can be explained from the existence of such terms too. If P_l is not broken by the vacuum values of the scalar fields, there is no mixing between the exotic and the ordinary quarks at the tree level.Comment: 20 pages, revised versio

Novel sources of Flavor Changed Neutral Currents in the 331RHN331_{RHN} model

Sources of Flavor Changed Neutral Currents (FCNC) naturally emerge from a well motivated framework called 3-3-1 with right-handed neutrinos model, $331_{RHN}$ for short, mediated by an extra neutral gauge boson $Z^{\prime}$. Following previous works we calculate these sources and in addition we derive new ones coming from CP-even and -odd neutral scalars which appear due to their non-diagonal interactions with the physical standard quarks. Furthermore we show that bounds related to the neutral mesons systems $K_L-K_S$ and $D_1^0 - D_2^0$ may be significantly strengthened in the presence of these new interactions allowing us to infer stronger constraints on the parameter space of the model.Comment: Published version. 10 pages, 6 figure

Stability of the Scalar Potential and Symmetry Breaking in the Economical 3-3-1 Model

A detailed study of the criteria for stability of the scalar potential and the proper electroweak symmetry breaking pattern in the economical 3-3-1 model, is presented. For the analysis we use, and improve, a method previously developed to study the scalar potential in the two-Higgs-doublet extension of the standard model. A new theorem related to the stability of the potential is stated. As a consequence of this study, the consistency of the economical 3-3-1 model emerges.Comment: to be published in EPJ C, 13 page

Phenomenological aspects of the exotic TT quark in 331 models

In the context of 331 models we analyze the phenomenology of exotic $T$ quarks with electric charge 2/3. We establish bounds for the corresponding masses and mixing angles and study the decay modes $T\to bW$, $tZ$ and $qH$. It is found that the decays into scalars are strongly dependent on the model parameters, and can be the dominant ones in a scenario with approximate flavor symmetry.Comment: 11 pages, 2 figure

Scalar Potential Without Cubic Term in 3-3-1 Models Without Exotic Electric Charges

A detailed study of the criteria for stability of the scalar potential, and the proper electroweak symmetry breaking pattern in some 3-3-1 models without exotic electric charges is presented. In this paper we concentrate in a scalar sector with three Higgs scalar triplets, with a potential that does not include the cubic term, due to the presence of a discrete symmetry. For the analysis we use, and improve, a method previously developed to study the scalar potential in the two-Higgs-doublet extension of the standard model. Our main result is to show the consistency of those 3-3-1 models without exotic electric charges.Comment: 19 page

Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma

William Lockwood and colleagues show that the focal amplification of a gene, BRF2, on Chromosome 8p12 plays a key role in squamous cell carcinoma of the lung