30,921 research outputs found
On the normalization of Killing vectors and energy conservation in two-dimensional gravity
We explicitly show that, in the context of a recently proposed 2D dilaton
gravity theory, energy conservation requires the ``natural'' Killing vector to
have, asymptotically, an unusual normalization. The Hawking temperature
is then calculated according to this prescription.Comment: 7 pages, Latex, no figure
Majocchi’s Granuloma by Trichophytum rubrum in a kidney transplant patient - A case report
Introduction: Trichophytum rubrum is a filamentous fungus, with worldwide distribution, that usually causes
superficial infections of skin and nails, namely tinea pedis, tinea corporis, tinea cruris and onychomycosis.
Rarely, severe dermatophytosis can occur, presenting as deep dermatophytosis, Majocchi’s Granuloma or
extensive dermatophytosis.
Objectives and Methods: Case report of Majocchi’s Granuloma in a kidney transplant patient.
Results: A case of a 55-year-old woman who underwent a kidney transplant 7 months before, under
immunosuppressive therapy with tacrolimus and mycophenolate mofetil. She attended a Dermatology
consultation to clarify skin lesions that appeared 6 months earlier. The skin exam revealed hard and painful
plaque lesions on both legs, with an ulcer on the left leg lesion, violaceous papular lesions on the dorsum of
the left foot and toes and a hard consistency nodule on the left leg. Some of the toe nails presented dystrophy
or onycholysis. The patient denied any previous trauma or contact with plants or soil.
Biopsies of lesions of the left leg and foot dorsum where sent for histology and mycological culture and toe
nails for mycological culture. The histological examinations showed, in the reticular dermis and reaching the
hypodermis, suppurative granulomas with multinucleated giant cells and areas of necrosis. PAS (Periodic Acid-
Schiff) and GMS (Grocott’s Methenamine Silver) staining revealed multiple spores and septate hypha within the
granulomas but not in the stratum corneum. No remnants of hair follicles where found.
Culture of skin biopsies were positive for Tricophytum rubrum but nails´ culture was negative.
Identification was further confirmed by sequencing of ITS region of ribosomal DNA (GenBank accession
number MK967277).
Oral Itraconazole 100mg bid and topic Sertoconazole where initiated. The patient was observed one month
after and reported general malaise, tiredness, exertional dyspnea, whitish stools and increased abdominal
volume. The physician chose to discontinue itraconazole and initiate oral terbinafine 250mg id. After two
months on oral terbinafine, there was regression of the legs´ and left foot lesions with ulcer healing and
disappearance of the left leg nodule.
Conclusion: Diagnosis of deeper dermatophytosis is difficult, in part because there is no specific clinical
presentation and, in many cases, it is even polymorphic. However, especially in patients with
immunodeficiency, this hypothesis should be weighed. Confirmation is achieved by finding hyphae compatible
with dermatophytes in the dermis and a positive culture for a dermatophyte.
Treatment should include systemic antifungal agents, to which topical medication may be associated. Multiple
therapeutic regimens have been proposed, but randomized trials or large case series are lacking. Antifungal
therapy should be continued until the lesions are completely resolved. Surgical treatment has been reported as
an option for highly localized lesions.info:eu-repo/semantics/publishedVersio
Use of beta agonists in feeding stuff in Portugal: an overview
We present a brief overview of the use of beta-agonists in feeding stuff in Portugal in the last two decades
Zinc content in liver and kidney of piglets slaughtered in Portugal
The aim of this work was the evaluation of zinc content in piglet’s liver and kidney, which was performed after detection of high concentration of this element in several pig’s feeding stuff in the analysis carried out under the official control, in Portugal. Determinations were executed by flame atomic absorption spectrophotometry (FAAS) after mineralization. Analytical quality control was carried out using control standards. A total of 46 piglets’ offals samples (23 livers and 23 kidneys) from the Aveiro’s district slaughterhouses were analyzed. As expected zinc was detected in all samples analyzed and concentrations were higher in liver than in kidney. The highest values found were 720.73 mg/kg in liver and 472.86 mg/kg in kidney (values considerably higher than usually reported in investigations carried out by different authors)
Free Fields for Chiral 2D Dilaton Gravity
We give an explicit canonical transformation which transforms a generic
chiral 2D dilaton gravity model into a free field theory.Comment: LaTeX file, 4 pages, to appear in Phys. Rev.
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