5,819 research outputs found
Prevalence of Forced Sex and Associated Factors among Women and Men in Kisumu, Kenya
Sexual violence is a well-recognized global health problem, albeit with limited population-based data available from sub-Saharan Africa. We sought to measure the prevalence of forced sex in Kisumu, Kenya, and identify its associated factors. The data were drawn from a population-based cross-sectional survey. A two-stage sampling design was used: 40 clusters within Kisumu municipality were enumerated and households within each cluster selected by systematic random sampling. Demographic and sexual histories, including questions on forced sex, were collected privately using a structured questionnaire. The prevalence of forced sex was 13% (women) and 4.5% (men). After adjusting for age and cluster, forced sex among women was associated with transactional sex (OR 2.33; 95%CI 1.38-3.95), having more than two lifetime partners (OR 1.9; 95%CI 1.20-3.30), having postprimary education (OR 1.49; 95%CI 1.04-2.14) and a high economic status (OR 1.87; 95%CI 1.2-2.9). No factors were significantly associated with forced sex among the male respondents. Intimate partners were the most common perpetrators of forced sex among both women (50%) and men (62.1%). Forced sex prevention programs need to target the identified associated factors, and educate the public on the high rate of forced sex perpetrated by intimate partners
Actinomycosis of the sigmoid colon: A case report
Abdominal actinomycosis is a chronic suppurative infection caused by Actinomyces species. The ileo-cecal region is most commonly affected, while the left side of the colon is more rarely involved. The infection has a tendency to infiltrate adjacent tissues and is therefore rarely confined to a single organ. Presentation may vary from non specific symptoms and signs to an acute abdomen. A computed tomography scan is helpful in identifying the inflammatory process and the organs involved. It also allows visual guidance for percutaneous drainage of abscesses, thus aiding diagnosis. Culture is difficult because of the anaerobic character and slow growth of actinomycetes. Colonoscopy is usually normal, but may shows signs of external compression. Preoperative diagnosis is rare and is established only in less than 10% of cases. In uncomplicated disease, high dose antibiotic therapy is the mainstay of treatment. Surgery is often performed because of a difficulty in diagnosis. Surgery and antibiotics are required in the case of complicated disease. Combined medical and surgical treatment achieves a cure in about 90% of cases. The authors report a case of sigmoid actinomycosis where diagnosis was made from the histology, and a review of the literature is presented
Ghrelin causes hyperphagia and obesity in rats.
Ghrelin, a circulating growth hormoneâreleasing pep-tide derived from the stomach, stimulates food intake. The lowest systemically effective orexigenic dose of ghrelin was investigated and the resulting plasma ghre-lin concentration was compared with that during fast-ing. The lowest dose of ghrelin that produced a significant stimulation of feeding after intraperitoneal injection was 1 nmol. The plasma ghrelin concentration after intraperitoneal injection of 1 nmol of ghrelin (2.83 0.13 pmol/ml at 60 min postinjection) was not significantly different from that occurring after a 24-h fast (2.79 0.32 pmol/ml). After microinjection into defined hypothalamic sites, ghrelin (30 pmol) stimu-lated food intake most markedly in the arcuate nucleus (Arc) (0â1 h food intake, 427 43 % of control; P <
Using smartâmessaging to enhance mindfulnessâbased cognitive therapy for cancer patients: A mixed methods proof of concept evaluation
Objective
Depression and anxiety lead to reduced treatment adherence, poorer quality of life, and increased care costs amongst cancer patients. Mindfulnessâbased cognitive therapy (MBCT) is an effective treatment, but dropout reduces potential benefits. Smartâmessage reminders can prevent dropout and improve effectiveness. However, smartâmessaging is untested for MBCT in cancer. This study evaluates smartâmessaging to reduce dropout and improve effectiveness in MBCT for cancer patients with depression or anxiety.MethodsFiftyâone cancer patients attending MBCT in a psychoâoncology service were offered a smartâmessaging intervention, which reminded them of prescribed betweenâsession activities. Thirty patients accepted smartâmessaging and 21 did not. Assessments of depression and anxiety were taken at baseline, sessionâbyâsession, and oneâmonth followâup. Logistic regression and multilevel modelling compared the groups on treatment completion and clinical effectiveness. Fifteen postâtreatment patient interviews explored smartâmessaging use.ResultsThe odds of programme completion were eight times greater for patients using smartâmessaging compared with nonâusers, controlling for age, gender, baseline depression, and baseline anxiety (OR = 7.79, 95% CI 1.75 to 34.58, p = .007). Smartâmessaging users also reported greater improvement in depression over the programme (B = â2.33, SEB = .78, p = .004) when controlling for baseline severity, change over time, age, and number of sessions attended. There was no difference between groups in anxiety improvement (B = â1.46, SEB = .86, p = .097). In interviews, smartâmessaging was described as a motivating reminder and source of personal connection. ConclusionsSmartâmessaging may be an easily integrated telehealth intervention to improve MBCT for cancer patients
Degenerate distributions in complex Langevin dynamics: one-dimensional QCD at finite chemical potential
We demonstrate analytically that complex Langevin dynamics can solve the sign
problem in one-dimensional QCD in the thermodynamic limit. In particular, it is
shown that the contributions from the complex and highly oscillating spectral
density of the Dirac operator to the chiral condensate are taken into account
correctly. We find an infinite number of classical fixed points of the Langevin
flow in the thermodynamic limit. The correct solution originates from a
continuum of degenerate distributions in the complexified space.Comment: 20 pages, several eps figures, minor comments added, to appear in
JHE
The Association of HIV Counseling and Testing with HIV Risk Behaviors in a Random Population-based Survey in Kisumu, Kenya
HIV testing has been promoted as a key HIV prevention strategy in low-resource settings, despite studies showing variable impact on risk behavior. We sought to examine rates of HIV testing and the association between testing and sexual risk behaviors in Kisumu, Kenya. Participants were interviewed about HIV testing and sexual risk behaviors. They then underwent HIV serologic testing. We found that 47% of women and 36% of men reported prior testing. Two-thirds of participants who tested HIV-positive in this study reported no prior HIV test. Women who had undergone recent testing were less likely to report high-risk behaviors than women who had never been tested; this was not seen among men. Although rates of HIV testing were higher than seen in previous studies, the majority of HIV-infected people were unaware of their status. Efforts should be made to increase HIV testing among this population
QCD with Chemical Potential in a Small Hyperspherical Box
To leading order in perturbation theory, we solve QCD, defined on a small
three sphere in the large N and Nf limit, at finite chemical potential and map
out the phase diagram in the (mu,T) plane. The action of QCD is complex in the
presence of a non-zero quark chemical potential which results in the sign
problem for lattice simulations. In the large N theory, which at low
temperatures becomes a conventional unitary matrix model with a complex action,
we find that the dominant contribution to the functional integral comes from
complexified gauge field configurations. For this reason the eigenvalues of the
Polyakov line lie off the unit circle on a contour in the complex plane. We
find at low temperatures that as mu passes one of the quark energy levels there
is a third-order Gross-Witten transition from a confined to a deconfined phase
and back again giving rise to a rich phase structure. We compare a range of
physical observables in the large N theory to those calculated numerically in
the theory with N=3. In the latter case there are no genuine phase transitions
in a finite volume but nevertheless the observables are remarkably similar to
the large N theory.Comment: 44 pages, 18 figures, jhep3 format. Small corrections and
clarifications added in v3. Conclusions cleaned up. Published versio
Application of quasi-Monte Carlo methods to PDEs with random coefficients -- an overview and tutorial
This article provides a high-level overview of some recent works on the
application of quasi-Monte Carlo (QMC) methods to PDEs with random
coefficients. It is based on an in-depth survey of a similar title by the same
authors, with an accompanying software package which is also briefly discussed
here. Embedded in this article is a step-by-step tutorial of the required
analysis for the setting known as the uniform case with first order QMC rules.
The aim of this article is to provide an easy entry point for QMC experts
wanting to start research in this direction and for PDE analysts and
practitioners wanting to tap into contemporary QMC theory and methods.Comment: arXiv admin note: text overlap with arXiv:1606.0661
Discomfort and agitation in older adults with dementia
<p>Abstract</p> <p>Background</p> <p>A majority of patients with dementia present behavioral and psychological symptoms, such as agitation, which may increase their suffering, be difficult to manage by caregivers, and precipitate institutionalization. Although internal factors, such as discomfort, may be associated with agitation in patients with dementia, little research has examined this question. The goal of this study is to document the relationship between discomfort and agitation (including agitation subtypes) in older adults suffering from dementia.</p> <p>Methods</p> <p>This correlational study used a cross-sectional design. Registered nurses (RNs) provided data on forty-nine residents from three long-term facilities. Discomfort, agitation, level of disability in performing activities of daily living (ADL), and severity of dementia were measured by RNs who were well acquainted with the residents, using the Discomfort Scale for patients with Dementia of the Alzheimer Type, the Cohen-Mansfield Agitation Inventory, the ADL subscale of the Functional Autonomy Measurement System, and the Functional Assessment Staging, respectively. RNs were given two weeks to complete and return all scales (i.e., the Cohen-Mansfield Agitation Inventory was completed at the end of the two weeks and all other scales were answered during this period). Other descriptive variables were obtained from the residents' medical file or care plan.</p> <p>Results</p> <p>Hierarchical multiple regression analyses controlling for residents' characteristics (sex, severity of dementia, and disability) show that discomfort explains a significant share of the variance in overall agitation (28%, <it>p </it>< 0.001), non aggressive physical behavior (18%, <it>p </it>< 0.01) and verbally agitated behavior (30%, <it>p </it>< 0.001). No significant relationship is observed between discomfort and aggressive behavior but the power to detect this specific relationship was low.</p> <p>Conclusion</p> <p>Our findings provide further evidence of the association between discomfort and agitation in persons with dementia and reveal that this association is particularly strong for verbally agitated behavior and non aggressive physical behavior.</p
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