43,026 research outputs found
Reconstruction of Quark Mass Matrices with Weak Basis Texture Zeroes from Experimental Input
All quark mass matrices with texture zeroes obtained through weak basis
transformations are confronted with the experimental data. The reconstruction
of the quark mass matrices M_u and M_d at the electroweak scale is performed in
a weak basis where the matrices are Hermitian and have a maximum of three
vanishing elements. The same procedure is also accomplished for the Yukawa
coupling matrices at the grand unification scale in the context of the Standard
Model and its minimal supersymmetric extension as well as of the two Higgs
doublet model. The analysis of all viable power structures on the quark Yukawa
coupling matrices that could naturally appear from a Froggatt-Nielsen mechanism
is also presented.Comment: RevTeX4, 3 tables, 21 pages; misprints corrected and one reference
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The Rules of Human T Cell Fate in vivo.
The processes governing lymphocyte fate (division, differentiation, and death), are typically assumed to be independent of cell age. This assumption has been challenged by a series of elegant studies which clearly show that, for murine cells in vitro, lymphocyte fate is age-dependent and that younger cells (i.e., cells which have recently divided) are less likely to divide or die. Here we investigate whether the same rules determine human T cell fate in vivo. We combined data from in vivo stable isotope labeling in healthy humans with stochastic, agent-based mathematical modeling. We show firstly that the choice of model paradigm has a large impact on parameter estimates obtained using stable isotope labeling i.e., different models fitted to the same data can yield very different estimates of T cell lifespan. Secondly, we found no evidence in humans in vivo to support the model in which younger T cells are less likely to divide or die. This age-dependent model never provided the best description of isotope labeling; this was true for naïve and memory, CD4+ and CD8+ T cells. Furthermore, this age-dependent model also failed to predict an independent data set in which the link between division and death was explored using Annexin V and deuterated glucose. In contrast, the age-independent model provided the best description of both naïve and memory T cell dynamics and was also able to predict the independent dataset
Coleman meets Schwinger
It is well known that spherical D-branes are nucleated in the presence of an
external RR electric field. Using the description of D-branes as solitons of
the tachyon field on non-BPS D-branes, we show that the brane nucleation
process can be seen as the decay of the tachyon false vacuum. This process can
describe the decay of flux-branes in string theory or the decay of quintessence
potentials arising in flux compactifications.Comment: 5 pages, 2 figure
Suite of simple metrics reveals common movement syndromes across vertebrate taxa
ecause empirical studies of animal movement are most-often site- and species-specific, we lack understanding of the level of consistency in movement patterns across diverse taxa, as well as a framework for quantitatively classifying movement patterns. We aim to address this gap by determining the extent to which statistical signatures of animal movement patterns recur across ecological systems. We assessed a suite of movement metrics derived from GPS trajectories of thirteen marine and terrestrial vertebrate species spanning three taxonomic classes, orders of magnitude in body size, and modes of movement (swimming, flying, walking). Using these metrics, we performed a principal components analysis and cluster analysis to determine if individuals organized into statistically distinct clusters. Finally, to identify and interpret commonalities within clusters, we compared them to computer-simulated idealized movement syndromes representing suites of correlated movement traits observed across taxa (migration, nomadism, territoriality, and central place foraging)
Há alguma diferença entre as próteses de disco cervicais?
Objetivo: A artroplastia cervical na patologia degenerativa surgiu como alternativa à artrodese anterior com o objetivo de eliminar a “doença do nível adjacente”. As próteses de disco apresentam diferentes materiais, design, técnica e mobilidade. Os autores avaliaram dor, disfunção e complicações para comparar a eficácia de diferentes próteses de disco.Material e Métodos: Foram analisadas retrospectivamente as próteses de disco cervical realizadas entre 2004 e 2010, com o total de 26 próteses em 22 doentes.
Os resultados de 5 próteses Baguera® foram comparados com 14 próteses Prestige®, 4 PCM® e 3 Bryan®.
Foi utilizada a escala visual analógica da dor (VAS), Neck Disability Index (NDI) e inquirido o grau de satisfação. Imagiologicamente foi determinada estabilidade, mobilidade e alterações degenerativas.Resultados: O follow-up das 5 próteses Baguera® foi 20.2±13.7 meses e nas restantes 21 próteses foi 55.2±15.8 meses (p=0.02).
A avaliação da dor não foi diferente. O grupo Baguera® apresenta superioridade na mobilidade (p=0.045), NDI pós-operatório (p=0.009) e melhoria do NDI global (p=0.01). Comparando doentes com disfunção nula/ligeira e severa/completa, a prótese Baguera® tem vantagem sobre as restantes 3 (p=0.04).
Ocorreram complicações em 4 (9.5%) doentes do grupo misto, com 2 reintervenções e 2 doentes com ossificação heterotrópica e perda total de mobilidade da prótese.Conclusão: A prótese de disco Baguera® apresenta superioridade em mobilidade e função, e apesar de diferente follow-up não apresenta complicações enquanto as restantes 3 próteses apresentam complicações e perda de mobilidade.
Estudos a longo prazo vão determinar se as vantagens teóricas continuam a traduzir benefícios clínicos
Toxicidade do óleo essencial de Piper tuberculatum (Jacq.) sobre Spodoptera frugiperda (Smith) em condições de campo.
Long-term Variability of HCO Masers in Star-forming Regions
We present results of a multi-epoch monitoring program on variability of
6cm formaldehyde (HCO) masers in the massive star forming region
NGC7538IRS1 from 2008 to 2015 conducted with the GBT, WSRT, and
VLA. We found that the similar variability behaviors of the two formaldehyde
maser velocity components in NGC7538IRS1 (which was pointed out by
Araya and collaborators in 2007) have continued. The possibility that the
variability is caused by changes in the maser amplification path in regions
with similar morphology and kinematics is discussed. We also observed
12.2GHz methanol and 22.2GHz water masers toward
NGC7538IRS1. The brightest maser components of CHOH and HO
species show a decrease in flux density as a function of time. The brightest
HCO maser component also shows a decrease in flux density and has a similar
LSR velocity to the brightest HO and 12.2GHz CHOH masers. The line
parameters of radio recombination lines and the 20.17 and 20.97GHz CHOH
transitions in NGC7538IRS1 are also reported. In addition, we
observed five other 6cm formaldehyde maser regions. We found no evidence of
significant variability of the 6cm masers in these regions with respect to
previous observations, the only possible exception being the maser in
G29.960.02. All six sources were also observed in the HCO
isotopologue transition of the 6cm HCO line; HCO absorption
was detected in five of the sources. Estimated column density ratios
[HCO]/[HCO] are reported.Comment: 29 pages, 9 figure
New Techniques for Relating Dynamically Close Galaxy Pairs to Merger and Accretion Rates : Application to the SSRS2 Redshift Survey
We introduce two new pair statistics, which relate close galaxy pairs to the
merger and accretion rates. We demonstrate the importance of correcting these
(and other) pair statistics for selection effects related to sample depth and
completeness. In particular, we highlight the severe bias that can result from
the use of a flux-limited survey. The first statistic, denoted N_c, gives the
number of companions per galaxy, within a specified range in absolute
magnitude. N_c is directly related to the galaxy merger rate. The second
statistic, called L_c, gives the total luminosity in companions, per galaxy.
This quantity can be used to investigate the mass accretion rate. Both N_c and
L_c are related to the galaxy correlation function and luminosity function in a
straightforward manner. We outline techniques which account for various
selection effects, and demonstrate the success of this approach using Monte
Carlo simulations. If one assumes that clustering is independent of luminosity
(which is appropriate for reasonable ranges in luminosity), then these
statistics may be applied to flux-limited surveys.
These techniques are applied to a sample of 5426 galaxies in the SSRS2
redshift survey. Using close dynamical pairs, we find N_c(-21<M_B<-18) =
0.0226+/-0.0052 and L_c(-21<M_B<-18) = 0.0216+/-0.0055 10^{10} h^2 L_sun at
z=0.015. These are the first secure estimates of low-z close pair statistics.
If N_c remains fixed with redshift, simple assumptions imply that ~ 6.6% of
present day galaxies with -21<M_B<-18 have undergone mergers since z=1. When
applied to redshift surveys of more distant galaxies, these techniques will
yield the first robust estimates of evolution in the galaxy merger and
accretion rates. [Abridged]Comment: 26 pages (including 10 postscript figures) plus 3 gif figures.
Accepted for publication in ApJ. Paper (including full resolution images)
also available at http://www.astro.utoronto.ca/~patton/ssrs2, along with
associated pair classification experiment (clickable version of Figure 5
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