22 research outputs found

    The economic return of classical studies

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    openUsing an IPWRA estimator, we estimate the effect of high school choice (classical lyceum vs scientific lyceum) on labour market outcomes. Morover, we investigate the existence of a gap in the return to college between classical and scientific studies

    Growth impairment after TBI of leukemia survivors children: a model-based investigation

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    Background: Children receiving Total Body Irradiation (TBI) in preparation for Hematopoietic Stem Cell Transplantation (HSCT) are at risk for Growth Hormone Deficiency (GHD), which sometimes severely compromises their Final Height (FH). To better represent the impact of such therapies on growth we apply a mathematical model, which accounts both for the gompertzian-like growth trend and the hormone-related ‘spurts', and evaluate how the parameter values estimated on the children undergoing TBI differ from those of the matched normal population. Methods: 25 patients long-term childhood lymphoblastic and myeloid acute leukaemia survivors followed at Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital (Turin, Italy) were retrospectively analysed for assessing the influence of TBI on their longitudinal growth and for validating a new method to estimate the GH therapy effects. Six were treated with GH therapy after a GHD diagnosis. Results: We show that when TBI was performed before puberty overall growth and pubertal duration were significantly impaired, but such growth limitations were completely reverted in the small sample (6 over 25) of children who underwent GH replacement therapies. Conclusion: Since in principle the model could account for any additional growth ‘spurt' induced by therapy, it may become a useful ‘simulation' tool for paediatricians for comparing the predicted therapy effectiveness depending on its timing and dosag

    Survival in Patients with Primary Parotid Gland Carcinoma after Surgery—Results of a Single-Centre Study

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    This study aims to analyse a single-centre cohort series of patients who underwent parotidectomy for primary malignant parotid tumours. A retrospective chart review of 64 consecutive patients treated from November 2010 to March 2022 was performed. Outcomes were analysed by Kaplan-Meier curves. Sixty-four patients with a primary parotid malignancy were included in the study, with one bilateral case in this cohort. Patients were classified as stage I–II in 39 cases and stage III–IV in 26 cases. The five-year overall survival (OS), disease-specific survival (DSS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) rates were 78.4%, 89%, 92.5%, and 87.1%, respectively. Univariate analysis showed that high-risk histology, stage IV disease, lymphovascular invasion, perineural invasion, node metastasis, skin involvement, facial nerve involvement, and positive or close margins were risk factors associated with poorer outcomes. At present, the best evidence suggests that radical surgery should be the standard approach, and adjuvant therapy, in terms of radiotherapy/chemoradiotherapy, is recommended in patients with risk factors

    Multi-walled carbon nanotubes decorated with titanium nanoparticles: synthesis and characterization

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    A chemical route to decorate MWCNTs by titanium nanoparticles has been developed. MWCNTs, grown by catalytic decomposition of propane, have been used to prepare intercalated K-MWCNTs, which are then reacted with Ti(IV) isopropoxide. The amount of Ti present in the nanostructure is 8.7 wt%. Several techniques have been used for a detailed characterization of MWCNTs decorated by Ti nanoparticles, such as transmission electron microscopy (TEM), selected-area electron diffraction (SAED), high resolution transmission electron microscopy (HREM) and electron energy loss spectroscopy (EELS) as well as Raman spectroscopy and x-ray diffraction (XRD). Titanium is found to be present as alpha-Ti(hcp) dispersed in very small particles, the size of the largest being similar to 2 nm. The Ti-containing phase appears to be fairly homogeneously distributed in the space between the two sides of a MWCNT. No intercalation of Ti between the CNT walls has been detected
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