6,427 research outputs found

    A pesquisa em agricultura familiar no semi-arido: metodos alternativos de diagnostico e validacao de tecnologias.

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    Abrigando mais da metade dos estabelecimentos rurais de base familiar do pais, o Nordeste brasileiro esta ameacado de ver a maior parte desse imenso potencial de trabalho e producao desaparecer, em funcao de politicas publicas de desenvolvimento ineficazes, em termos de permitir uma efetiva insercao dessas unidades no mercado, de modo especial na regiao semi-arida. A pesquisa agricola compartilha responsabilidade nesse processo, uma vez que nao foi capaz de incorporar as suas acoes uma visao mais abrangente da problematica do agricultor familiar. Essa situacao comeca, contudo a se modificar na regiao. As experiencias de construcao de metodologias multidisciplinares e participativas adaptadas a realidades locais, comecam a se multiplicar, prenunciando a obtencao de resultados mais objetivos pela pesquisa. Tres dessas metodologias, o zoneamento municipal em unidades de desenvolvimento, o diagnostico rapido dos circuitos de comercializacao e transformacao e a validacao de tecnologias atraves dos testes de ajuste, descritas neste trabalho, sao exemplos desse esforco da pesquisa na busca de uma maior objetividade

    Caracterizacao social e economica da videira.

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    Introdução; Evolução do cultivo da videira; Importância econômica e social da videira na região

    Projeto Gavião: impactos (meio período) do desenvolvimento rural - 1998/2001.

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    Infestação de plantas espontâneas em cultivo de café solteiro ou consorciado com banana em sistema agroecológico.

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    bitstream/item/69051/1/062-germani-infestacao.pdfPublicado também no Cadernos de Agroecologia, v. 7, n.2, 2012

    Target-Oriented Synthesis of Marine Coelenterazine Derivatives with Anticancer Activity by Applying the Heavy-Atom Effect

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    Photodynamic therapy (PDT) is an anticancer therapeutic modality with remarkable advantages over more conventional approaches. However, PDT is greatly limited by its dependence on external light sources. Given this, PDT would benefit from new systems capable of a light-free and intracellular photodynamic effect. Herein, we evaluated the heavy-atom effect as a strategy to provide anticancer activity to derivatives of coelenterazine, a chemiluminescent single-molecule widespread in marine organisms. Our results indicate that the use of the heavy-atom effect allows these molecules to generate readily available triplet states in a chemiluminescent reaction triggered by a cancer marker. Cytotoxicity assays in different cancer cell lines showed a heavy-atom-dependent anticancer activity, which increased in the substituent order of hydroxyl < chlorine < bromine. Furthermore, it was found that the magnitude of this anticancer activity is also dependent on the tumor type, being more relevant toward breast and prostate cancer. The compounds also showed moderate activity toward neuroblastoma, while showing limited activity toward colon cancer. In conclusion, the present results indicate that the application of the heavy-atom effect to marine coelenterazine could be a promising approach for the future development of new and optimized self-activating and tumor-selective sensitizers for light-free PDT

    Which are the best practices for MSc programmes in Sustainable Agriculture?

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    Programmes of education for sustainable development are important to reformulate and revise educa tional programmes in Sustainable Agriculture. Higher education institutes emerge as learning places to integrate sustainable development into the educational system, through graduation and MSc pro grammes, to provide a more effective response to the higher environmental and agriculture concerns. The aim of this study was to identify the best practices to be included in a MSc programme of education for sustainable development in agriculture based on a questionnaire prepared and distributed to agrarian sciences experts. The questionnaires were developed in order to define the fundamental competences/ expertise, to identify the best practices and the methods of training/learning that should be taken in consideration in a MSc programme in Sustainable Agriculture. The results showed that the fundamental expertise of MSc programmes should be based on knowledge transfer of agricultural measures to mitigate the impact of climate change on agricultural systems. MSc programmes in Sustainable Agri culture should include interdisciplinary courses related to sustainability and agro-environmental tech nologies, such as Precision Agriculture, and incorporate adaptive and mitigate practices as those used in the Circular Economy strategy. Traditional face-to-face training methods are considered the most important forms of training/learning in a MSc programme in Sustainable Agriculture. However, due to COVID-19 pandemic, online learning methods, traditionally considered not suitable for MSc programme in Sustainable Agriculture, became important by providing online education. Information and commu nication technology and technological tools showed to be important skills to effectively implement online learning and to improve the efficient access and use of up-to-date information of the agricultural sector
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