Servo-controlled intravital microscope system

A microscope system is described for viewing an area of a living body tissue that is rapidly moving, by maintaining the same area in the field-of-view and in focus. A focus sensing portion of the system includes two video cameras at which the viewed image is projected, one camera being slightly in front of the image plane and the other slightly behind it. A focus sensing circuit for each camera differentiates certain high frequency components of the video signal and then detects them and passes them through a low pass filter, to provide dc focus signal whose magnitudes represent the degree of focus. An error signal equal to the difference between the focus signals, drives a servo that moves the microscope objective so that an in-focus view is delivered to an image viewing/recording camera

Automatically-focusing microscope system for live tissue observation

System includes focus-sensing arrangement which controls servo to keep microscope constantly focused on target. Microscope objective is moved along optical axis. System includes two video cameras that are used as transducers for sensing focus. Incoming visual image is split by beam splitter so that one-half of information is fed to each camera

Podiatry services for patients with arthritis: an unmet need

Foot problems are extremely common in patients with rheumatoid arthritis (RA). There is ample evidence that foot pain, either alone or as a comorbidity, contributes significantly to disability. Despite the high prevalence of foot disease in RA, this problem is often trivialised or underappreciated. The inequity in foot health provision for patients with rheumatic disorders in New Zealand has recently been highlighted. Expertise in dealing with foot problems is often limited among healthcare professionals, and it has been argued that better integration of podiatric services into rheumatology services would be beneficial. The aim of this paper is to highlight the major issues related to foot care for patients with arthritis and provide key recommendations that should implemented to improve access to podiatric services in New Zealand

An investigation for the development of an integrated optical data preprocessor

A laboratory model of a 16 channel integrated optical data preprocessor was fabricated and tested in response to a need for a device to evaluate the outputs of a set of remote sensors. It does this by accepting the outputs of these sensors, in parallel, as the components of a multidimensional vector descriptive of the data and comparing this vector to one or more reference vectors which are used to classify the data set. The comparison is performed by taking the difference between the signal and reference vectors. The preprocessor is wholly integrated upon the surface of a LiNbO3 single crystal with the exceptions of the source and the detector. He-Ne laser light is coupled in and out of the waveguide by prism couplers. The integrated optical circuit consists of a titanium infused waveguide pattern, electrode structures and grating beam splitters. The waveguide and electrode patterns, by virtue of their complexity, make the vector subtraction device the most complex integrated optical structure fabricated to date

Pinwheel stabilization by ocular dominance segregation

We present an analytical approach for studying the coupled development of ocular dominance and orientation preference columns. Using this approach we demonstrate that ocular dominance segregation can induce the stabilization and even the production of pinwheels by their crystallization in two types of periodic lattices. Pinwheel crystallization depends on the overall dominance of one eye over the other, a condition that is fulfilled during early cortical development. Increasing the strength of inter-map coupling induces a transition from pinwheel-free stripe solutions to intermediate and high pinwheel density states.Comment: 10 pages, 4 figure

The Redshift Distribution of the TOUGH Survey

We present the redshift results from a Very Large Telescope program aimed at optimizing the legacy value of the Swift mission: to characterize a homogeneous, X-ray selected, sample of 69 GRB host galaxies. 19 new redshifts have been secured, resulting in a 83% (57/69) redshift completion, making the survey the most comprehensive in terms of redshift completeness of any sample to the full Swift depth, available to date. We present the cumulative redshift distribution and derive a conservative, yet small, associated uncertainty. We constrain the fraction of Swift GRBs at high redshift to a maximum of 10% (5%) for z > 6 (z > 7). The mean redshift of the host sample is assessed to be > 2.2. Using this more complete sample, we confirm previous findings that the GRB rate at high redshift (z > 3) appears to be in excess of predictions based on assumptions that it should follow conventional determinations of the star formation history of the universe, combined with an estimate of its likely metallicity dependence. This suggests that either star formation at high redshifts has been significantly underestimated, for example due to a dominant contribution from faint, undetected galaxies, or that GRB production is enhanced in the conditions of early star formation, beyond those usually ascribed to lower metallicity.Comment: 7th Huntsville Gamma-Ray Burst Symposium, GRB 2013: paper 34 in eConf Proceedings C130414

Photoionization and Photoelectric Loading of Barium Ion Traps

Simple and effective techniques for loading barium ions into linear Paul traps are demonstrated. Two-step photoionization of neutral barium is achieved using a weak intercombination line (6s2 1S0 6s6p 3P1, 791 nm) followed by excitation above the ionization threshold using a nitrogen gas laser (337 nm). Isotopic selectivity is achieved by using a near Doppler-free geometry for excitation of the triplet 6s6p 3P1 state. Additionally, we report a particularly simple and efficient trap loading technique that employs an in-expensive UV epoxy curing lamp to generate photoelectrons.Comment: 5 pages, Accepted to PRA 3/20/2007 -fixed typo -clarified figure 3 caption -added reference [15

Macroscopic control parameter for avalanche models for bursty transport

Similarity analysis is used to identify the control parameter RA for the subset of avalanching systems that can exhibit self-organized criticality (SOC). This parameter expresses the ratio of driving to dissipation. The transition to SOC, when the number of excited degrees of freedom is maximal, is found to occur when RA-->0. This is in the opposite sense to (Kolmogorov) turbulence, thus identifying a deep distinction between turbulence and SOC and suggesting an observable property that could distinguish them. A corollary of this similarity analysis is that SOC phenomenology, that is, power law scaling of avalanches, can persist for finite RA with the same RA-->0 exponent if the system supports a sufficiently large range of lengthscales, necessary for SOC to be a candidate for physical (RA finite) systems

The VOISE Algorithm: a Versatile Tool for Automatic Segmentation of Astronomical Images

The auroras on Jupiter and Saturn can be studied with a high sensitivity and resolution by the Hubble Space Telescope (HST) ultraviolet (UV) and far-ultraviolet (FUV) Space Telescope spectrograph (STIS) and Advanced Camera for Surveys (ACS) instruments. We present results of automatic detection and segmentation of Jupiter's auroral emissions as observed by HST ACS instrument with VOronoi Image SEgmentation (VOISE). VOISE is a dynamic algorithm for partitioning the underlying pixel grid of an image into regions according to a prescribed homogeneity criterion. The algorithm consists of an iterative procedure that dynamically constructs a tessellation of the image plane based on a Voronoi Diagram, until the intensity of the underlying image within each region is classified as homogeneous. The computed tessellations allow the extraction of quantitative information about the auroral features such as mean intensity, latitudinal and longitudinal extents and length scales. These outputs thus represent a more automated and objective method of characterising auroral emissions than manual inspection.Comment: 9 pages, 7 figures; accepted for publication in MNRA

Magnetic Field Structure around Low-Mass Class 0 Protostars: B335, L1527 and IC348-SMM2

We report new 350 micron polarization observations of the thermal dust emission from the cores surrounding the low-mass, Class 0 YSOs L1527, IC348-SMM2 and B335. We have inferred magnetic field directions from these observations, and have used them together with results in the literature to determine whether magnetically regulated core-collapse and star-formation models are consistent with the observations. These models predict a pseudo-disk with its symmetry axis aligned with the core magnetic field. The models also predict a magnetic field pinch structure on a scale less than or comparable to the infall radii for these sources. In addition, if the core magnetic field aligns (or nearly aligns) the core rotation axis with the magnetic field before core collapse, then the models predict the alignment (or near alignment) of the overall pinch field structure with the bipolar outflows in these sources. We show that if one includes the distorting effects of bipolar outflows on magnetic fields, then in general the observational results for L1527 and IC348-SMM2 are consistent with these magnetically regulated models. We can say the same for B335 only if we assume the distorting effects of the bipolar outflow on the magnetic fields within the B335 core are much greater than for L1527 and IC348-SMM2. We show that the energy densities of the outflows in all three sources are large enough to distort the magnetic fields predicted by magnetically regulated models.Comment: Accepted for publication in The Astrophysical Journa