2,828 research outputs found
A Study of a Casual relationship between Performance Appraisal and Employee’s Performance: Evidence from the Textile Sector in Faisalabad
Employee performance is the strength of the organization. This study relates to the assessment of the relationship between employee performance evaluations to assess the moderate role of motivation. The current research was conducted in Faisalabad's textile industry. A sample of 204 respondents was drawn using a convenient sampling technique. In addition, the primary information was collected through a questionnaire. For data analysis, SPSS (version-20) software applied percentage, mean, standard deviation, regression and correlation coefficient methods. The result is achievable in a positive relationship between the outcome of the conversion and the employee's earnings. Another variable is motivation, because the moderator has a positive effect between the two relationships. The textile industry can use the evaluation rule as a deliberate approach by integrating it into its business policy and HR practice and improving the employee's performance in the organization
Can we use postal surveys with anonymous testing to monitor chlamydia prevalence in young women in England? Pilot study incorporating randomised controlled trial of recruitment methods
OBJECTIVES: Chlamydia prevalence in the general population is a potential outcome measure for the evaluation of chlamydia control programmes. We carried out a pilot study to determine the feasibility of using a postal survey for population-based chlamydia prevalence monitoring.
METHODS: Postal invitations were sent to a random sample of 2000 17-year-old to 18-year-old women registered with a general practitioner in two pilot areas in England. Recipients were randomised to receive either a self-sampling kit (n=1000), a self-sampling kit and offer of £5 voucher on return of sample (n=500) or a self-sampling kit on request (n=500). Participants returned a questionnaire and self-taken vulvovaginal swab sample for unlinked anonymous Chlamydia trachomatis testing. Non-responders were sent a reminder letter 3 weeks after initial invitation. We calculated the participation rate (number of samples returned/number of invitations sent) and cost per sample returned (including cost of consumables and postage) in each group.
RESULTS: A total of 155/2000 (7.8%) samples were returned with consent for testing. Participation rates varied by invitation group: 7.8% in the group who were provided with a self-sampling kit, 14% in the group who were also offered a voucher and 1.0% in the group who were not sent a kit. The cost per sample received was lowest (£36) in the group who were offered both a kit and a voucher.
CONCLUSIONS: The piloted survey methodology achieved low participation rates. This approach is not suitable for population-based monitoring of chlamydia prevalence among young women in England
Phylogenetic Analysis and Rapid Identification of the Whitefly, Bemisia afer, in China
The phylogenetic relationship between the whitefly Bemisia afer (Priesner & Hosny) (Hemiptera: Aleyrodidae) from China and other populations among the world were analyzed based on the mitochondrial cytochrome oxidase I (mtCOI) gene. Phylogenetic analysis of mtCOI sequences and those of reference B. afer sequences showed that the populations of the species could be separated into 5 clades (I–V). There were at least two clades of the species from China (IV and V). These data suggested that B. afer might be a species complex. The Chinese B. afer populations were most divergent with B. afer from the United Kingdom and African countries. The distance between the Chinese B. afer (IV and V) and clades I, II, and III is more than 32%, while the distance among clades I, II, III is lower than 7.7%. A new set of primers specific to B. afer was designed to amplify a region of approximately 400 bp to discriminate B. afer from other Bemisia species in China based on mtCOI sequences
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Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a primary care setting.
BACKGROUND: Alzheimer's disease and other forms of dementia are becoming increasingly common with the aging of most populations. The majority of individuals with dementia will first present for care and assessment in primary care settings. There is a need for brief dementia screening instruments that can accurately diagnose dementia in primary care settings. The Mini-Cog is a brief, cognitive screening test that is frequently used to evaluate cognition in older adults in various settings. OBJECTIVES: To determine the diagnostic accuracy of the Mini-Cog for diagnosing Alzheimer's disease dementia and related dementias in a primary care setting. SEARCH METHODS: We searched the Cochrane Dementia and Cognitive Improvement Register of Diagnostic Test Accuracy Studies, MEDLINE, Embase and four other databases, initially to September 2012. Since then, four updates to the search were performed using the same search methods, and the most recent was January 2017. We used citation tracking (using the databases' 'related articles' feature, where available) as an additional search method and contacted authors of eligible studies for unpublished data. SELECTION CRITERIA: We only included studies that evaluated the Mini-Cog as an index test for the diagnosis of Alzheimer's disease dementia or related forms of dementia when compared to a reference standard using validated criteria for dementia. We only included studies that were conducted in primary care populations. DATA COLLECTION AND ANALYSIS: We extracted and described information on the characteristics of the study participants and study setting. Using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) criteria we evaluated the quality of studies, and we assessed risk of bias and applicability of each study for each domain in QUADAS-2. Two review authors independently extracted information on the true positives, true negatives, false positives, and false negatives and entered the data into Review Manager 5 (RevMan 5). We then used RevMan 5 to determine the sensitivity, specificity, and 95% confidence intervals. We summarized the sensitivity and specificity of the Mini-Cog in the individual studies in forest plots and also plotted them in a receiver operating characteristic plot. We also created a 'Risk of bias' and applicability concerns graph to summarize information related to the quality of included studies. MAIN RESULTS: There were a total of four studies that met our inclusion criteria, including a total of 1517 total participants. The sensitivity of the Mini-Cog varied between 0.76 to 1.00 in studies while the specificity varied between 0.27 to 0.85. The included studies displayed significant heterogeneity in both methodologies and clinical populations, which did not allow for a meta-analysis to be completed. Only one study (Holsinger 2012) was found to be at low risk of bias on all methodological domains. The results of this study reported that the sensitivity of the Mini-Cog was 0.76 and the specificity was 0.73. We found the quality of all other included studies to be low due to a high risk of bias with methodological limitations primarily in their selection of participants. AUTHORS' CONCLUSIONS: There is a limited number of studies evaluating the accuracy of the Mini-Cog for the diagnosis of dementia in primary care settings. Given the small number of studies, the wide range in estimates of the accuracy of the Mini-Cog, and methodological limitations identified in most of the studies, at the present time there is insufficient evidence to recommend that the Mini-Cog be used as a screening test for dementia in primary care. Further studies are required to determine the accuracy of Mini-Cog in primary care and whether this tool has sufficient diagnostic test accuracy to be useful as a screening test in this setting
Recommended from our members
Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a community setting.
BACKGROUND: Alzheimer's disease and related forms of dementia are becoming increasingly prevalent with the aging of many populations. The diagnosis of Alzheimer's disease relies on tests to evaluate cognition and discriminate between individuals with dementia and those without dementia. The Mini-Cog is a brief, cognitive screening test that is frequently used to evaluate cognition in older adults in various settings. OBJECTIVES: The primary objective of this review was to determine the diagnostic accuracy of the Mini-Cog for detecting Alzheimer's disease dementia and related dementias in a community setting.Secondary objectives included investigations of the heterogeneity of test accuracy in the included studies and potential sources of heterogeneity. These potential sources of heterogeneity included the baseline prevalence of dementia in study samples, thresholds used to determine positive test results, the type of dementia (Alzheimer's disease dementia or all causes of dementia), and aspects of study design related to study quality. Overall, the goals of this review were to determine if the Mini-Cog is a cognitive screening test that could be recommended to screen for cognitive impairment in community settings. SEARCH METHODS: We searched MEDLINE (OvidSP), EMBASE (OvidSP), PsycINFO (Ovid SP), Science Citation Index (Web of Science), BIOSIS previews (Web of Science), LILACS (BIREME), and the Cochrane Dementia Group's developing register of diagnostic test accuracy studies to March 2013. We used citation tracking (using the database's 'related articles' feature, where available) as an additional search method and contacted authors of eligible studies for unpublished data. SELECTION CRITERIA: We included all cross-sectional studies that utilized the Mini-Cog as an index test for the diagnosis of dementia when compared to a reference standard diagnosis of dementia using standardized dementia diagnostic criteria. For the current review we only included studies that were conducted on samples from community settings, and excluded studies that were conducted in primary care or secondary care settings. We considered studies to be conducted in a community setting where participants were sampled from the general population. DATA COLLECTION AND ANALYSIS: Information from studies meeting the inclusion criteria were extracted including information on the characteristics of participants in the studies. The quality of the studies was assessed using the QUADAS-2 criteria and summarized using risk of bias applicability and summary graphs. We extracted information on the diagnostic test accuracy of studies including the sensitivity, specificity, and 95% confidence intervals of these measures and summarized the findings using forest plots. Study specific sensitivities and specificities were also plotted in receiver operating curve space. MAIN RESULTS: Three studies met the inclusion criteria, with a total of 1620 participants. The sensitivities of the Mini-Cog in the individual studies were reported as 0.99, 0.76 and 0.99. The specificity of the Mini-Cog varied in the individual studies and was 0.93, 0.89 and 0.83. There was clinical and methodological heterogeneity between the studies which precluded a pooled meta-analysis of the results. Methodological limitations were present in all the studies introducing potential sources of bias, specifically with respect to the methods for participant selection. AUTHORS' CONCLUSIONS: There are currently few studies assessing the diagnostic test accuracy of the Mini-Cog in community settings. The limited number of studies and the methodological limitations that are present in the current studies make it difficult to provide recommendations for or against the use of the Mini-Cog as a cognitive screening test in community settings. Additional well-designed studies comparing the Mini-Cog to other brief cognitive screening tests are required in order to determine the accuracy and utility of the Mini-Cog in community based settings
Development of a strontium optical lattice clock for the SOC mission on the ISS
The ESA mission "Space Optical Clock" project aims at operating an optical
lattice clock on the ISS in approximately 2023. The scientific goals of the
mission are to perform tests of fundamental physics, to enable space-assisted
relativistic geodesy and to intercompare optical clocks on the ground using
microwave and optical links. The performance goal of the space clock is less
than uncertainty and
instability. Within an EU-FP7-funded project, a strontium optical lattice clock
demonstrator has been developed. Goal performances are instability below and fractional inaccuracy .
For the design of the clock, techniques and approaches suitable for later space
application are used, such as modular design, diode lasers, low power
consumption subunits, and compact dimensions. The Sr clock apparatus is fully
operational, and the clock transition in Sr was observed with linewidth
as small as 9 Hz.Comment: 12 pages, 8 figures, SPIE Photonics Europe 201
An addressable quantum dot qubit with fault-tolerant control fidelity
Exciting progress towards spin-based quantum computing has recently been made
with qubits realized using nitrogen-vacancy (N-V) centers in diamond and
phosphorus atoms in silicon, including the demonstration of long coherence
times made possible by the presence of spin-free isotopes of carbon and
silicon. However, despite promising single-atom nanotechnologies, there remain
substantial challenges in coupling such qubits and addressing them
individually. Conversely, lithographically defined quantum dots have an
exchange coupling that can be precisely engineered, but strong coupling to
noise has severely limited their dephasing times and control fidelities. Here
we combine the best aspects of both spin qubit schemes and demonstrate a
gate-addressable quantum dot qubit in isotopically engineered silicon with a
control fidelity of 99.6%, obtained via Clifford based randomized benchmarking
and consistent with that required for fault-tolerant quantum computing. This
qubit has orders of magnitude improved coherence times compared with other
quantum dot qubits, with T_2* = 120 mus and T_2 = 28 ms. By gate-voltage tuning
of the electron g*-factor, we can Stark shift the electron spin resonance (ESR)
frequency by more than 3000 times the 2.4 kHz ESR linewidth, providing a direct
path to large-scale arrays of addressable high-fidelity qubits that are
compatible with existing manufacturing technologies
Development of a strontium optical lattice clock for the SOC mission on the ISS
Ultra-precise optical clocks in space will allow new studies in fundamental
physics and astronomy. Within an European Space Agency (ESA) program, the Space
Optical Clocks (SOC) project aims to install and to operate an optical lattice
clock on the International Space Station (ISS) towards the end of this decade.
It would be a natural follow-on to the ACES mission, improving its performance
by at least one order of magnitude. The payload is planned to include an
optical lattice clock, as well as a frequency comb, a microwave link, and an
optical link for comparisons of the ISS clock with ground clocks located in
several countries and continents. Within the EU-FP7-SPACE-2010-1 project no.
263500, during the years 2011-2015 a compact, modular and robust strontium
lattice optical clock demonstrator has been developed. Goal performance is a
fractional frequency instability below 1x10^{-15}, tau^{-1/2} and a fractional
inaccuracy below 5x10^{-17}. Here we describe the current status of the
apparatus' development, including the laser subsystems. Robust preparation of
cold {88}^Sr atoms in a second stage magneto-optical trap (MOT) is achieved.Comment: 27 Pages, 15 figures, Comptes Rendus Physique 201
The Space Optical Clocks Project: Development of high-performance transportable and breadboard optical clocks and advanced subsystems
The use of ultra-precise optical clocks in space ("master clocks") will allow
for a range of new applications in the fields of fundamental physics (tests of
Einstein's theory of General Relativity, time and frequency metrology by means
of the comparison of distant terrestrial clocks), geophysics (mapping of the
gravitational potential of Earth), and astronomy (providing local oscillators
for radio ranging and interferometry in space). Within the ELIPS-3 program of
ESA, the "Space Optical Clocks" (SOC) project aims to install and to operate an
optical lattice clock on the ISS towards the end of this decade, as a natural
follow-on to the ACES mission, improving its performance by at least one order
of magnitude. The payload is planned to include an optical lattice clock, as
well as a frequency comb, a microwave link, and an optical link for comparisons
of the ISS clock with ground clocks located in several countries and
continents. Undertaking a necessary step towards optical clocks in space, the
EU-FP7-SPACE-2010-1 project no. 263500 (SOC2) (2011-2015) aims at two
"engineering confidence", accurate transportable lattice optical clock
demonstrators having relative frequency instability below 1\times10^-15 at 1 s
integration time and relative inaccuracy below 5\times10^-17. This goal
performance is about 2 and 1 orders better in instability and inaccuracy,
respectively, than today's best transportable clocks. The devices will be based
on trapped neutral ytterbium and strontium atoms. One device will be a
breadboard. The two systems will be validated in laboratory environments and
their performance will be established by comparison with laboratory optical
clocks and primary frequency standards. In this paper we present the project
and the results achieved during the first year.Comment: Contribution to European Frequency and Time Forum 2012, Gothenburg,
Swede
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