Enophthalmos caused by an orbital venous malformation

Orbital vascular malformations usually present with proptosis. We report a case where a patient with an orbital venous malformation presented with enophthalmos. Since many underlying orbital pathologies, including orbital metastases, can cause enophthalmos, it is important to investigate patients properly. Computed tomographic imaging of the orbit remains the most useful tool in the management of patients with enophthalmos.published_or_final_versio

Orbital myiasis complicating squamous cell carcinoma of eyelid

Myiasis is infestation of the body by fly maggots. Immobile patients with skin wounds in exposed areas are at high risk of developing myiasis. We report a case of orbital myiasis from the species Chrysomya bezziana complicating squamous cell carcinoma of the eyelid. Magnetic resonance imaging of the orbit is useful for delineating the extent of the infestation and identifying residual maggots. In extensive orbital myiasis, exenteration is needed to prevent intracranial extension of tissue destruction.published_or_final_versio

Digital evidence search kit

With the rapid development of electronic commerce and Internet technology, cyber crimes have become more and more common. There is a great need for automated software systems that can assist law enforcement agencies in cyber crime evidence collection. This paper describes a cyber crime evidence collection tool called DESK (Digital Evidence Search Kit), which is the product of several years of cumulative efforts of our Center together with the Hong Kong Police Force and several other law enforcement agencies of the Hong Kong Special Administrative Region. We will use DESK to illustrate some of the desirable features of an effective cyber crime evidence collection tool. © 2005 IEEE.published_or_final_versio

A retrospective analysis of complications of treatment of nevus of Ota with the Q-switched Alexandrite (QS Alex) and Q-switched Neodymium: Yttrium-Aluminum-Garnet (QS Nd-YAG) lasers

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Validity and Reliability of Curl-Up Test on Assessing the Core Endurance for Kindergarten Children in Hong Kong

Objective: The purpose of this study was to examine the test-retest reliability and the criterion validity of a curlup test (CUT) as a measure of core stability, core endurance and dynamic stability in kindergarten children. CUT performance was also compared to half hold lying test (HHLT) and walking time on course (WTC) among without obstacle, with low obstacle and high obstacle measures of core stability, core endurance and dynamic stability. Methods: To estimate reliability, 33 males and 27 female kindergarten children (M aged=4.5 years old) performed the CUT on 2 different days. In the validity phase of the study, scores of all participants were obtained on three field test measures of core stability, core endurance and dynamic stability (CUT, HHLT and WTC). Results: Results indicate that the MCU test has no significant correlation on intra-class test-retest reliability (R=0.13, p>0.01). The criterion validity of the CUT for kindergarten children has is comparable to that of the HHLT(r=0.98, p<0.01) and WTC without obstacle(r=0.96, p<0.01), with low obstacle (r=0.96, p<0.01) and with high obstacle (r=0.98, p<0.01). Result indicates that the CUT test cannot produces reasonably accurate and stable measures of core stability, core endurance and dynamic stability. Conclusion: These preliminary findings provide evidences into the CUT test cannot produces reasonably accurate and stable measures of core stability, core endurance and dynamic stability for kindergarten children

Nevus of Ota: a new classification based upon the response to laser treatment

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A new model using routinely available clinical parameters to predict significant liver fibrosis in chronic hepatitis B

Objective: We developed a predictive model for significant fibrosis in chronic hepatitis B (CHB) based on routinely available clinical parameters. Methods: 237 treatment-naïve CHB patients [58.4% hepatitis B e antigen (HBeAg)-positive] who had undergone liver biopsy were randomly divided into two cohorts: training group (n = 108) and validation group (n = 129). Liver histology was assessed for fibrosis. All common demographics, viral serology, viral load and liver biochemistry were analyzed. Results: Based on 12 available clinical parameters (age, sex, HBeAg status, HBV DNA, platelet, albumin, bilirubin, ALT, AST, ALP, GGT and AFP), a model to predict significant liver fibrosis (Ishak fibrosis score ≥3) was derived using the five best parameters (age, ALP, AST, AFP and platelet). Using the formula log(index+1) = 0.025+0.0031(age)+0.1483 log(ALP)+0.004 log(AST)+0.0908 log(AFP+1)-0.028 log(platelet), the PAPAS (Platelet/Age/Phosphatase/AFP/AST) index predicts significant fibrosis with an area under the receiving operating characteristics (AUROC) curve of 0.776 [0.797 for patients with ALT <2×upper limit of normal (ULN)] The negative predictive value to exclude significant fibrosis was 88.4%. This predictive power is superior to other non-invasive models using common parameters, including the AST/platelet/GGT/AFP (APGA) index, AST/platelet ratio index (APRI), and the FIB-4 index (AUROC of 0.757, 0.708 and 0.723 respectively). Using the PAPAS index, 67.5% of liver biopsies for patients being considered for treatment with ALT <2×ULN could be avoided. Conclusion: The PAPAS index can predict and exclude significant fibrosis, and may reduce the need for liver biopsy in CHB patients. © 2011 Seto et al.published_or_final_versio

Dysmenorrhoea among Hong Kong university students: prevalence, impact, and management

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Protecting digital legal professional privilege LPP data

The Best Paper AwardTo enable free communication between legal advisor and his client for proper functioning of the legal system, certain documents, known as Legal professional privilege (LPP) documents, can be excluded as evidence for prosecution. In physical world, protection of LPP information is well addressed and proper procedure for handling LPP articles has been established. However, there does not exist a forensically sound procedure for protecting 'digital' LPP information. In this paper, we try to address this important, but rarely addressed, issue. We point out the difficulties of handling digital LPP data and discuss the shortcomings of the current practices, then we propose a feasible procedure for solving this problem. © 2008 IEEE.published_or_final_versionThe 3rd International Workshop on Systematic Approaches to Digital Forensic Engineering (IEEE/SADFE 2008), Oakland, CA., 22 May 2008. In Proceedings of the 3rd SADFE, 2008, p. 91-10

Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons.

BACKGROUND: Establishing correct neuronal circuitry is crucial to proper function of the vertebrate nervous system. The abundance of chondroitin sulfate (CS) proteoglycans in embryonic neural environments suggests that matrix proteoglycans regulate axonal projections when fiber tracts have not yet formed. Among the early-born neurons, the vestibular nucleus (VN) neurons initiate commissural projections soon after generation at E12.5 and reach the contralateral target by E15.5 in the rat hindbrain. We therefore exploited 24-hour cultures (1 day in vitro (DIV)) of the rat embryos and chondroitinase ABC treatment of the hindbrain matrix to reveal the role of CS moieties in axonal initiation and projection in the early hindbrain. RESULTS: DiI tracing from the VN at E12.5(+1 DIV) showed contralaterally projecting fibers assuming fascicles that hardly reached the midline in the controls. In the enzyme-treated embryos, the majority of fibers were unfasciculated as they crossed the midline at 90°. At E13.5(+1 DIV), the commissural projections formed fascicles and crossed the midline in the controls. Enzyme treatment apparently did not affect the pioneer axons that had advanced as thick fascicles normal to the midline and beyond, towards the contralateral VN. Later projections, however, traversed the enzyme-treated matrix as unfasciculated fibers, deviated from the normal course crossing the midline at various angles and extending beyond the contralateral VN. This suggests that CSs also limit the course of the later projections, which otherwise would be attracted to alternative targets. CONCLUSIONS: CS moieties in the early hindbrain therefore control the course and fasciculation of axonal projections and the timing of axonal arrival at the target.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are