5 research outputs found
Analysis of B-genome derived simple sequence repeat (SSR) markers in Musa spp.
A study was conducted to investigate the genetic variability between 40 Musa genotypes maintained at the Musa germplasm collection of the International Institute for Tropical Agriculture, Ibadan using nine B-genome derived simple sequence repeat (SSR) markers. The nine primers produced reproducible and discrete fragments and generated a total of 23 alleles with an average of 2.1. The hierarchical cluster analysis showed clusters of diploid cultivars separate from triploid ones (with the exception of TMB149 (BB) and TMB131 (AB)). Average gene diversity was He = 0.412, and differentiation, given by the fixation index (FST) was low at 0.13
Analysis of B-genome derived simple sequence repeat (SSR) markers in Musa spp.
A study was conducted to investigate the genetic variability between 40 Musa genotypes maintained at the Musa germplasm collection of the International Institute for Tropical Agriculture, Ibadan using nine B-genome derived simple sequence repeat (SSR) markers. The nine primers produced reproducible and discrete fragments and generated a total of 23 alleles with an average of 2.1. The hierarchical cluster analysis showed clusters of diploid cultivars separate from triploid ones (with the exception of TMB149 (BB) and TMB131 (AB)). Average gene diversity was He = 0.412, and differentiation, given by the fixation index (FST) was low at 0.131.Keywords: Banana, genetic diversity, gene differentiation, plantai
Reactive community-based self-administered treatment against residual malaria transmission: study protocol for a randomized controlled trial
Background: Systematic treatment of all individuals living in the same compound of a clinical malaria case may
clear asymptomatic infections and possibly reduce malaria transmission, where this is focal. High and sustained
coverage is extremely important and requires active community engagement. This study explores a communitybased
approach to treating malaria case contacts.
Methods/design: This is a cluster-randomized trial to determine whether, in low-transmission areas, treating
individuals living in the same compound of a clinical malaria case with dihydroartemisinin-piperaquine can reduce
parasite carriage and thus residual malaria transmission. Treatment will be administered through the local health
system with the approach of encouraging community participation designed and monitored through formative
research. The trial goal is to show that this approach can reduce in intervention villages the prevalence of
Plasmodium falciparum infection toward the end of the malaria transmission season.
Discussion: Adherence and cooperation of the local communities are critical for the success of mass treatment
campaigns aimed at reducing malaria transmission. By exploring community perceptions of the changing trends in
malaria burden, existing health systems, and reaction to self-administered treatment, this study will develop and
adapt a model for community engagement toward malaria elimination that is cost-effective and fits within the
existing health system.
Trial registration: Clinical trials.gov, NCT02878200. Registered on 25 August 2016