10,766 research outputs found

    Degradation and breakdown characteristics of thin MgO dielectric layers

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    MgO has been suggested as a possible high-k dielectric for future complementary metal-oxide semiconductor processes. In this work, the time dependent dielectric breakdown (TDDB) characteristics of 20 nm MgO films are discussed. Stress induced leakage current measurements indicate that the low measured Weibull slopes of the TDDB distributions for both n-type and p-type devices cannot be attributed to a lower trap generation rate than for SiO2. This suggests that much fewer defects are required to trigger breakdown in MgO under voltage stress than is the case for SiO2 or other metal-oxide dielectrics. This in turn explains the progressive nature of the breakdown in these films which is observed both in this work and elsewhere. The reason fewer defects are required is attributed to the morphology of the films

    Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics

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    Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity determined

    Spin-Echo Measurements for an Anomalous Quantum Phase of 2D Helium-3

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    Previous heat-capacity measurements of our group had shown the possible existence of an anomalous quantum phase containing the zero-point vacancies (ZPVs) in 2D 3^{3}He. The system is monolayer 3^{3}He adsorbed on graphite preplated with monolayer 4^{4}He at densities (ρ\rho) just below the 4/7 commensurate phase (0.8ρ/ρ4/710.8\leq \rho /\rho_{4/7}\leq 1). We carried out pulsed-NMR measurements in order to examine the microscopic and dynamical nature of this phase. The measured decay of spin echo signals shows the non-exponential behaviour. The decay curve can be fitted with the double exponential function, but the relative intensity of the component with a longer time constant is small (5%) and does not depend on density and temperature, which contradicts the macroscopic fluid and 4/7 phase coexistence model. This slowdown is likely due to the mosaic angle spread of Grafoil substrate and the anisotropic spin-spin relaxation time T2T_{2} in 2D systems with respect to the magnetic field direction. The inverse T2T_2 value deduced from the major echo signal with a shorter time constant, which obeys the single exponential function, decreases linearly with decreasing density from n=1n=1, supporting the ZPV model.Comment: 4 pages, 6 figure

    Behavioral Assessment of Emotion Discrimination, Emotion Regulation, and Cognitive Control in Childhood, Adolescence, and Adulthood

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    Emotion discrimination, emotion regulation, and cognitive control are three related, yet separable processes that emerge over the course of development. The current study tested 100 children, adolescents, and adults on an Emotional Go/Nogo task, illustrating the ability of this paradigm to identify the unique developmental patterns for each of these three processes in the context of both positive (happy) and negative emotions (fear, sad, and anger), across three different age groups. Consistent with previous literature, our findings show that emotion discrimination and regulatory abilities (both cognitive control and emotion regulation) improve steadily for each age group, with each age group showing unique patterns of performance. The findings suggest that emotion regulation is constructed from basic cognition control and emotion discrimination skills. The patterns of behavior from the Emotional Go/Nogo task provide normative benchmark data across a wide range of emotions that can be used for future behavioral and neuroimaging studies that examine the developmental construction of emotion regulatory processes

    Pharmacokinetics of a syrup formulation of amoxycillin-potassium clavulanate in children

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    The pharmacokinetics of a syrup formulation consisting of four parts of amoxycillin and one part of potassium clavulanate (Augmentin) were studied in 11 paediatric patients, 3 to 14 years of age. Single oral doses of 25 mg of Augmentin per kg body weight (20 mg of amoxycillin per kg plus 5 mg of potassium clavulanate per kg, i.e. 1 mg of the syrup per kg) were administered on an empty stomach, and were well accepted and tolerated. Mean peak plasma concentrations 60-90 min after dosing were 7.2 mg/l for amoxycillin and 2-0 mg/l for clavulanic acid. Mean terminal phase plasma half-lifes were 1.4 and 1.0 h, respectively. It is concluded that 25-mg/kg doses of this syrup formulation of Augmentin administered three times daily should be adequate therapy for various childhood bacterial infection
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