Arrival Directions of Cosmic Rays above 32 EeV from Phase One of the Pierre Auger Observatory

A promising energy range to look for angular correlations between cosmic rays of extragalactic origin and their sources is at the highest energies, above a few tens of EeV (1 EeV equivalent to 10^(18) eV). Despite the flux of these particles being extremely low, the area of similar to 3000 km^(2) covered at the Pierre Auger Observatory, and the 17 yr data-taking period of the Phase 1 of its operations, have enabled us to measure the arrival directions of more than 2600 ultra-high-energy cosmic rays above 32 EeV. We publish this data set, the largest available at such energies from an integrated exposure of 122,000 km^(2) sr yr, and search it for anisotropies over the 3.4 pi steradians covered with the Observatory. Evidence for a deviation in excess of isotropy at intermediate angular scales, with similar to 15 degrees Gaussian spread or similar to 25 degrees top-hat radius, is obtained at the 4 sigma significance level for cosmic-ray energies above similar to 40 EeV

Search for Ultra-high-energy Photons from Gravitational Wave Sources with the Pierre Auger Observatory

A search for time-directional coincidences of ultra-high-energy (UHE) photons above 10 EeV with gravitational wave (GW) events from the LIGO/Virgo runs O1 to O3 is conducted with the Pierre Auger Observatory. Due to the distinctive properties of photon interactions and to the background expected from hadronic showers, a subset of the most interesting GW events is selected based on their localization quality and distance. Time periods of 1000 s around and 1 day after the GW events are analyzed. No coincidences are observed. Upper limits on the UHE photon fluence from a GW event are derived that are typically at & SIM;7 MeV cm(-2) (time period 1000 s) and & SIM;35 MeV cm(-2) (time period 1 day). Due to the proximity of the binary neutron star merger GW170817, the energy of the source transferred into UHE photons above 40 EeV is constrained to be less than 20% of its total GW energy. These are the first limits on UHE photons from GW sources

Searches for Ultra-High-Energy Photons at the Pierre Auger Observatory

The Pierre Auger Observatory, which is the largest air-shower experiment in the world, offers unprecedented exposure to neutral particles at the highest energies. Since the start of data collection more than 18 years ago, various searches for ultra-high-energy (UHE, E greater than or similar to 10^(17) eV) photons have been performed, either for a diffuse flux of UHE photons, for point sources of UHE photons or for UHE photons associated with transient events such as gravitational wave events. In the present paper, we summarize these searches and review the current results obtained using the wealth of data collected by the Pierre Auger Observatory

Densidade de plantio de cultivares de cenoura para processamento submetidas à adubações química e orgânica Planting density of carrot cultivars for industrialization under organic and chemical fertilization

O objetivo deste trabalho foi verificar a produtividade das cultivares de cenoura Alvorada e Carandaí em diferentes densidades de plantio utilizando-se adubações química e orgânica, visando a produção de matéria-prima para o processamento de cenouretes e catetinhos. Foram utilizadas as densidades: 16; 20; 24; 28 e 32 plantas por metro linear, sendo as parcelas compostas por 10 linhas transversais ao sentido do canteiro, com 1 m de comprimento entre si. O delineamento experimental utilizado foi de blocos casualizados em arranjo fatorial 2x2x5 (duas cultivares, dois tipos de adubação e cinco densidades de plantio) com quatro repetições. Foram avaliados: peso total de raízes, estimativa de produtividade, comprimento de raízes, raízes com diâmetro menor que 3,0 cm (%), raízes com ombro verde (%), sobras para o processamento (%), descarte (%) e severidade da queima das folhas. A colheita foi feita aos 104 dias após o plantio. O peso total de raízes e raízes com diâmetro inferior a 3,0 cm não foram influenciados pelo tipo de adubação. O aumento da densidade reduziu a produção de raízes com diâmetro superior a 3,0 cm e o comprimento médio das raízes. Quando utilizou-se adubação química ocorreu maior presença de raízes com ombro verde e a cultivar Alvorada apresentou as maiores porcentagens de raízes com esta característica.<br>In this research the yield of Alvorada and Carandaí carrot cultivars was verified, under different planting densities, submitted to organic and chemical fertilization, aiming to obtain roots with adequate characteristics for cenourete production (similar to baby carrot) and catetinho (mini ball form). Five planting densities were used: 16; 20; 24; 28 and 32 plants m-1) with four replications, in a total of 80 plots of 10 lines spaced 0,25 m from each other. The total root weight, average root length, roots with smaller diameter than 3,0 cm (%), roots with green superior part (%),leftovers for processing (%),discard (%) and the severity of leaf blight were evaluated. Plants were harvested 104 days after sowing. Total root weight and percentage of root diameter smaller than 3,0 cm were not influenced by the type of fertilization. Increasing the planting density resulted in a reduction of the root weight with a diameter over 3,0 cm as well as in the root length, independently of the cultivar. Using chemical fertilization resulted in more roots with green shoulder independently of the employed cultivar; but Alvorada presented higher percentages of green shoulder

The activity of flavones and oleanolic acid from Lippia lacunosa against susceptible and resistant Mycobacterium tuberculosis strains

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is the world’s number one killer among infectious diseases. The search for new natural products that can act as drugs against TB has received increased attention during the last years. In this work we describe the isolation and identification of the active antimycobacterial principles of the dichloromethane extract from Lippia lacunosa Mart. & Schauer, Verbenaceae. Compounds were evaluated for their in vitro activity against Mycobacterium tuberculosis (susceptible and rifampicin resistant strain) using a redox bioassay. From the dichloromethane extract of L. lacunosa leaves, seven methoxy-flavones named cirsimaritin (1), eupatilin (2), eupatorin (3), salvigenin (4), 3′-O-methyl-eupatorin (5), 3′,7-dimethoxy-5,6,4′- trihydroxyflavone (6), and 7′-O-methylapigenin (7), and one triterpene, named oleanolic acid (8), were isolated. All compounds were found to display antimycobacterial activity against susceptible strain, with MIC ranging from 25 to 200 μg/mL. None of them was active against rifampicin resistant strain. This is the first report in the antimycobacterial activity of 6-substituted flavones, as well as the first report of the occurrence of these substances in L. lacunosa