Dermoscopy of Cylindroma

Background. Dermoscopy provides additional criteria for the diagnosis of nonpigmented skin lesions. Case Report. An 80-year-old woman presented with an isolated, firm, dome-shaped, erythematous nodule with surface telangiectasia on her forehead. Dermoscopy showed areas of background pink coloration with arborizing telangiectasia, blue dots/globules, and ulceration. Histologic analysis revealed features of cylindroma. Conclusion. Our case suggests that cylindromas may be added to the list of adnexal tumors mimicking BCC

Overdrive short pulse high peak power diode lasers without catastrophic optical damage

Light Imaging Detection and Ranging (LIDAR) and Optoacoustic biomedical imaging techniques are applications that have a specific laser source requirements: short pulses, high peak power per pulse and high repetition rates. A custom current driver has been designed to fulfill these requirements and characterized in order to generate high current short pulses to drive High Power Diode Lasers (HPDL) beyond their maximum rating value, with a maximum current capacity of 120 A in a range of less than 10 nanoseconds pulse width, rise times up to 2 ns and a repetition rate of 1 kHz. Four commercial HPDLs have been driven generating optical pulses of less than 10 ns and more than four times the maximum rated optical peak power. A single laser device reached a maximum peak power of 880.6 W at 6 ns pulse width, demonstrating stable operation without catastrophic optical damage and improving the typical operation characteristics of the HPDLs for high speed short pulse applications.This work was supported by Comunidad de Madrid under Grant S2018/NMT-4333 MARTINLARA-CM project within the Programa de Actividades de I+D entre grupos de investigación de la Comunidad de Madrid en Tecnologías 2018

Invited Article: Experimental evaluation of gold nanoparticles as infrared scatterers for advanced cardiovascular optical imaging

Documento escrito por un elevado número de autores/as, solo se referencia el/la que aparece en primer lugar y los/las autores/as pertenecientes a la UC3MThe tremendous impact that cardiovascular diseases have in modern society is motivating the research of novel imaging techniques that would make possible early diagnosis and, therefore, efficient treatments. Cardiovascular optical coherence tomography (CV-OCT) emerged as a result of such a demand, and it has already been used at the clinical level. Full utilization of CV-OCT requires the development of novel contrast molecular agents characterized by a large scattering efficiency in the infrared (800-1400 nm). Gold nanoparticles (GNPs) seem to be the best candidates, but their scattering properties in the infrared are hardly known. In most of the cases, scattering properties are extracted from numerical simulations. This knowledge gap here is covered by providing an experimental evaluation of the infrared scattering properties of different GNPs (nanoshells, nanostars, and nanorods). These GNPs display remarkable extinction coefficients in the first and second biological windows, including the particular CV-OCT wavelength. We use a unique combination of techniques (thermal loading experiments, infrared optical coherence tomography, infrared dark field microscopy, and optoacoustic spectroscopy) to experimentally determine the scattering efficiency at three different near-infrared wavelengths (808 nm, 980 nm, and 1280 nm), lying in the first and second biological windows. Consequently, this work determines experimentally the influence of particle morphology on the infrared scattering efficiency of GNPs and evidences the existence of remarkable discrepancies between experimental data and numerical simulations. (C) 2018 Author(s).This work was supported by the Spanish Ministerio de Economía y Competitividad under Project No. MAT2016-75362-C3-1-R. J.A.S.-G. and D.R.A. acknowledge the partial financial support from the Spanish Ministerio de Economía y Competitividad  through the grant LENSBEAM (No. FIS2015-69295-C3-2-P), Ministerio de Educación, Cultura y Deporte through a Ph.D. Fellowship (No. FPU15/03566), and also Consejo Superior de Investigaciones Científicas (i-COOP LIGHT 2015CD0011). J.H. acknowledges the scholarship from the China Scholarship Council (CSC, No. 201506650003). D.T. and P.R.G. acknowledge the Mineco and MdM Excellence Intiative (Nos. FJCI-2014-22398, RYC-2012-10059, CTQ2013-45433-P[FEDER], and MDM-2014-0370-04)

Renovación de pasto llorón (Eragrotis curvula) mediante el arado cinceles en la región semiárida pampeana

PosterEl objetivo de este trabajo es evaluar el nivel de producción de forraje del pasto llorón, y otras gramíneas forrajeras y no forrajeras naturales por efecto del tratamiento mecánico del cincelEEA AnguilFil: Kent, Federico. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Cabo, Sergio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Ruiz, María de los Angeles. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; Argentina. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Beneitez, Adrian Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Lorda, Hector. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; Argentin

Recurrent melanocytic nevi and melanomas in dermoscopy: results of a multicenter study of the International Dermoscopy Society

IMPORTANCE Differentiating recurrent nevi from recurrent melanoma is challenging. OBJECTIVE To determine dermoscopic features to differentiate recurrent nevi from melanomas. DESIGN, SETTING, AND PARTICIPANTS Retrospective observational study of 15 pigmented lesion clinics from 12 countries; 98 recurrent nevi (61.3%) and 62 recurrent melanomas (38.8%) were collected from January to December 2011. MAIN OUTCOMES AND MEASURES Scoring the dermoscopic features, patterns, and colors in correlation with the histopathologic findings. RESULTS In univariate analysis, radial lines, symmetry, and centrifugal growth pattern were significantly more common dermoscopically in recurrent nevi; in contrast, circles, especially if on the head and neck area, eccentric hyperpigmentation at the periphery, a chaotic and noncontinuous growth pattern, and pigmentation beyond the scar's edge were significantly more common in recurrent melanomas. Patients with recurrent melanomas were significantly older than patients with recurrent nevi (mean [SD] age, 63.1 [17.5] years vs 30.2 [12.4] years) (P<.001), and there was a significantly longer time interval between the first procedure and the second treatment (median time interval, 25 vs 8 months) (P<.001). In a multivariate analysis, pigmentation beyond the scar's edge (P=.002), age (P<.001), and anatomic site (P=.002) were significantly and independently associated with the diagnosis of recurrent melanoma in dermoscopy. CONCLUSIONS AND RELEVANCE Dermoscopically, pigmentation beyond the scar's edge is the strongest clue for melanoma. Dermoscopy is helpful in evaluating recurrent lesions, but final interpretation requires taking into account the patient age, anatomic site, time to recurrence, growth pattern, and, if available, the histopathologic findings of the first excision

Renormalized Path Integral for the Two-Dimensional Delta-Function Interaction

A path-integral approach for delta-function potentials is presented. Particular attention is paid to the two-dimensional case, which illustrates the realization of a quantum anomaly for a scale invariant problem in quantum mechanics. Our treatment is based on an infinite summation of perturbation theory that captures the nonperturbative nature of the delta-function bound state. The well-known singular character of the two-dimensional delta-function potential is dealt with by considering the renormalized path integral resulting from a variety of schemes: dimensional, momentum-cutoff, and real-space regularization. Moreover, compatibility of the bound-state and scattering sectors is shown.Comment: 26 pages. The paper was significantly expanded and numerous equations were added for the sake of clarity; the main results and conclusions are unchange

Agregado de semilla de Piptochaetium napostaense para rehabilitación del pastizal en áreas intervenidas de bosque de calden

PosterEl Bosque de Caldén requiere de intervenciones que permitan recuperar y/o potenciar los bienes y servicios ecosistémicos que brinda. En un establecimiento del caldenal pampeano, se intervinieron dos áreas: topadora con rastrillo (TR) y raleo manual selectivo (RMS). Con el objetivo de rehabilitar el pastizal de estas áreas, se sembraron semillas de Piptochaetium napostaense.EEA AnguilFil: Porta Siota, Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Sawczuk, Natalia. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Suarez, Carla. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Morici, Ernesto Francisco. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; Argentina. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Petruzzi, Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional la Pampa-San Luis; Argentina. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Ernst, Ricardo. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; Argentina. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Estelrich, Hector Daniel. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Butti, Lucas Ramiro. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Agencia de Extensión Rural Guatrache; ArgentinaFil: Cabo, Sergio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Poey, María Sol. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Agencia de Extensión Rural Victorica; ArgentinaFil: Breit, Milton Adrian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Agencia de Extensión Rural Victorica; ArgentinaFil: Ruiz, María de los Angeles. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; Argentin

Rehabilitación de pastizales naturales a partir de la siembra con forrajeras nativas en La Pampa

PosterEl objetivo de este trabajo fue evaluar el establecimiento de especies forrajeras nativas a partir de una intervención antrópica (quema, aleo selectivo, topadora), seguida de la siembra de estas especies nativas en sectores carentes de banco de semilla de las mismas con la finalidad de mejorar el pastizal.EEA INTA AnguilFil: Cabo, Sergio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Ruiz, María de los Angeles. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Porta Siota, Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Poey, María Sol. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Agencia de Extensión Rural Victorica; ArgentinaFil: Breit, Milton Adrian. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Agencia de Extensión Rural Victorica; ArgentinaFil: Butti, Lucas Ramiro. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Agencia de Extensión Rural Guatrache; ArgentinaFil: Ernst, Ricardo. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; Argentina. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Sawczuk, Natalia. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Fuentes, María Elena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil; ArgentinaFil: Petruzzi, Horacio. Instituto Nacional de Tecnología Agropecuaria (INTA). Centro Regional la Pampa-San Luis; ArgentinaFil: Suarez, Carla. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Morici, Ernesto Francisco. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales; Argentina. Universidad Nacional de La Pampa. Facultad de Agronomía; ArgentinaFil: Estelrich, Hector Daniel. Universidad Nacional de La Pampa. Facultad de Agronomía; Argentin

Characterization of individuals at high risk of developing melanoma in Latin America: bases for genetic counseling in melanoma

PURPOSE: CDKN2A is the main high-risk melanoma-susceptibility gene, but it has been poorly assessed in Latin America. We sought to analyze CDKN2A and MC1R in patients from Latin America with familial and sporadic multiple primary melanoma (SMP) and compare the data with those for patients from Spain to establish bases for melanoma genetic counseling in Latin America. METHODS: CDKN2A and MC1R were sequenced in 186 Latin American patients from Argentina, Brazil, Chile, Mexico, and Uruguay, and in 904 Spanish patients. Clinical and phenotypic data were obtained. RESULTS: Overall, 24 and 14% of melanoma-prone families in Latin America and Spain, respectively, had mutations in CDKN2A. Latin American families had CDKN2A mutations more frequently (P = 0.014) than Spanish ones. Of patients with SMP, 10% of those from Latin America and 8.5% of those from Spain had mutations in CDKN2A (P = 0.623). The most recurrent CDKN2A mutations were c.-34G>T and p.G101W. Latin American patients had fairer hair (P = 0.016) and skin (P < 0.001) and a higher prevalence of MC1R variants (P = 0.003) compared with Spanish patients. CONCLUSION: The inclusion criteria for genetic counseling of melanoma in Latin America may be the same criteria used in Spain, as suggested in areas with low to medium incidence, SMP with at least two melanomas, or families with at least two cases among first- or second-degree relatives.Genet Med 18 7, 727-736

Dermoscopic evaluation of nodular melanoma

Importance: Nodular melanoma (NM) is a rapidly progressing potentially lethal skin tumor for which early diagnosis is critical