755 research outputs found

    Numerical computations for singular semilinear elliptic boundary value problems

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    AbstractThe paper studies a class of Dirichlet problems with homogeneous boundary conditions for singular semilinear elliptic equations in a bounded smooth domain in . A numerical method is devised to construct an approximate Green's function by using radial basis functions and the method of fundamental solutions. An estimate of the error involved is also given. A weak solution of the above given problem is a solution of its corresponding nonlinear integral equation. A computational method is given to find the minimal weak solution U, and the critical index λ* (such that a weak solution U exists for λ < λ*, and U does not exist for λ > λ*)

    Skin thickness of the anterior, anteromedial, and anterolateral thigh: a cadaveric study for split-skin graft donor sites

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    Background: The depth of graft harvest and the residual dermis available for reepithelization primarily influence the healing of split-skin graft donor sites. When the thigh region is chosen, the authors hypothesize based on thickness measurements that the anterolateral region is the optimal donor site. Methods: Full-thickness skin specimens were sampled from the anteromedial, anterior, and anterolateral regions of human cadavers. Skin specimens were cut perpendicularly with a custom-made precision apparatus to avoid the overestimation of thickness measurements. The combined epidermal and dermal thicknesses (overall skin thickness) were measured using a digital calliper. The specimens were histologically stained to visualize their basement membrane, and microscopy images were captured. Since the epidermal thickness varies across the specimen, a stereological method was used to eliminate observer bias. Results: Epidermal thickness represented 2.5% to 9.9% of the overall skin thickness. There was a significant difference in epidermal thickness from one region to another (P&#60;0.05). The anterolateral thigh region had the most consistent and highest mean epidermal thickness (60±3.2 µm). We observed that overall skin thickness increased laterally from the anteromedial region to the anterior and anterolateral regions of the thigh. The overall skin thickness measured 1,032±435 µm in the anteromedial region compared to 1,220±257 µm in the anterolateral region. Conclusions: Based on skin thickness measurements, the anterolateral thigh had the thickest epidermal and dermal layers. We suggest that the anterolateral thigh region is the optimal donor site for split-skin graft harvests from the thigh

    Hemiplegia in Men: A Case Study

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    Hemiplegia, or paralysis of one side of the body, is caused by injury or illness (for example, a stroke), and leads to other disabilities. People with hemiplegia are limited physically in their daily activities. This limitation affects their social well-being and thus can lead to depression. This paper provides a comprehensive literature review on hemiplegia in men. A single case study of a man with hemiplegia living in Hong Kong is also presented here. A critical discussion of the signs and symptoms of “male-type” depression and humanising attitudes towards men with hemiplegia follows. Critical areas in rehabilitation, social support, and developing partnerships are also highlighted. This paper intends to facilitate better understanding by health and social care providers of the needs of men with hemiplegia. Implications for clinical practice and research are likewise addressed. Further studies using multiple case studies are recommended to ensure a comprehensive understanding of hemiplegia in men

    Anorexic Eating: Two Case Studies in Hong Kong

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    Little attention has been paid to the eating experience of anorectic females during the course of their illness. In order to enrich this understanding, two adult anorexics were selected and their emails were collected and analyzed. Analysis of these emails reveals the patients\u27 experiences with and feelings about eating, which can provide an in-depth understanding of their circumstances and family dynamics. The paper ends with a discussion of the results, limitations, and implications of using emails as the data source of a qualitative study, and how they can reveal the informants\u27 inner landscapes

    Client Service Receipt Inventory as a standardised tool for measurement of socio-economic costs in the rare genetic disease population (CSRI-Ra)

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    The measurement of costs is fundamental in healthcare decision-making, but it is often challenging. In particular, standardised methods have not been developed in the rare genetic disease population. A reliable and valid tool is critical for research to be locally meaningful yet internationally comparable. Herein, we sought to develop, contextualise, translate, and validate the Client Service Receipt Inventory for the RAre disease population (CSRI-Ra) to be used in cost-of-illness studies and economic evaluations for healthcare planning. Through expert panel discussions and focus group meetings involving 17 rare disease patients, carers, and healthcare and social care professionals from Hong Kong, we have developed the CSRI-Ra. Rounds of forward and backward translations were performed by bilingual researchers, and face validity and semantic equivalence were achieved through interviews and telephone communications with focus group participants and an additional of 13 healthcare professional and university students. Intra-class correlation coefficient (ICC) was used to assess criterion validity between CSRI-Ra and electronic patient record in a sample of 94 rare disease patients and carers, with overall ICC being 0.69 (95% CI 0.56–0.78), indicating moderate to good agreement. Following rounds of revision in the development, contextualisation, translation, and validation stages, the CSRI-Ra is ready for use in empirical research. The CSRI-Ra provides a sufficiently standardised yet adaptable method for collecting socio-economic data related to rare genetic diseases. This is important for near-term and long-term monitoring of the resource consequences of rare diseases, and it provides a tool for use in economic evaluations in the future, thereby helping to inform planning for efficient and effective healthcare. Adaptation of the CSRI-Ra to other populations would facilitate international research

    Fish to 2050 in the ASEAN region

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    The Association of Southeast Asian Nations (ASEAN) has emerged as a global fish producer, owing to the rapid growth of aquaculture in Southeast Asia and its large offshore fishing fleet. Fish is a regional commodity that is traded globally, and this region is at the frontline of the global trend toward meeting seafood demand by 2050. Fisheries and aquaculture are increasingly becoming a primary source of protein and micronutrients, foreign exchange, livelihoods and well-being for the population in the region. Therefore, it is imperative for ASEAN decision-makers to enhance policies nationally and regionally to maximize the synergies between socioeconomic development and protecting natural resources and the environment in the region. This paper presents a baseline (business-as-usual) projection of fish supply, net trade, consumption and nutrition in the ASEAN region to 2050
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