5 research outputs found

    Obésité (ob) adulte : Evolution sur 11 ans et facteurs prédictifs a Bamako : Study of adult obesity (OB): Evolution over 11 years and predictive factors in Bamako

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    Objectif Evaluer la prĂ©valence et les prĂ©dicteurs de l'obĂ©sitĂ© chez l'adulte dans la population gĂ©nĂ©rale.MĂ©thodologie Il s’agissait d’une Ă©tude comparative entre 2002 et 2013 de l’obĂ©sitĂ© en population gĂ©nĂ©rale sur des sujets ĂągĂ©s de 20 ans et plus. Les enquĂȘtes ont Ă©tĂ© menĂ©es selon la procĂ©dure STEP de l’OMSL’obĂ©sitĂ© a Ă©tĂ© Ă©valuĂ©e sur l’indice de masse corporelle (IMC) et le tout de taille (TT).Les analyses ont Ă©tĂ© rĂ©alisĂ©es en utilisant SPSS et le seuil de significativĂ© fixĂ© Ă  0,05.RĂ©sultats L’échantillon comprenait 1237 sujets ĂągĂ©s de 20 ans au moins avec une prĂ©dominance masculine. La proportion de sujets avec des facteurs de risque cardiovasculaires Ă©tait plus importante en 2013 avec 6% de tabagiques, 16,7% d’hypertendus et 9,1% de diabĂ©tique.Les moyennes pour l’ñge, l’IMC, le TT ainsi que la PAD Ă©taient plus Ă©levĂ©es en 2013 avec des diffĂ©rences respectives de 4,27 ans, 2,23 Kg/m2, 8,25 cm et 0,37 mmHgLa prĂ©valence de l’obĂ©sitĂ© basĂ©e sur l’IMC a passĂ© de 3,2% en 2002 Ă  11,5% en 2013 et celle basĂ©e sur le TT 16,5 Ă  33,2.Les facteurs prĂ©dictifs de l’obĂ©sitĂ© Ă©taient le sexe fĂ©minin, l’ñge entre 30-44 ans et l’hypertension artĂ©rielle.ConclusionLa prĂ©valence de l’obĂ©sitĂ© augmente d’oĂč la nĂ©cessitĂ© d’une surveillance plus attentive. Les programmes de lutte contre le surpoids et l’obĂ©sitĂ© doivent ĂȘtre Ă©laborĂ©s au mĂȘme titre que ceux pour le diabĂšte et l’hypertension artĂ©rielle Objective to assess the prevalence and predictors of adult obesity in the general population.Methodology This was a comparative study of obesity in the general population on subjects aged 20 and over. The surveys were conducted according to the WHO STEP procedureObesity was assessed on body mass index (BMI) and waist circumference (WC).Analyzes were performed using SPSS and the significance level set at 0.05.Results The sample included 1237 subjects aged 20 or over with a male predominance. The proportion of subjects with cardiovascular risk factors was higher in 2013 with 6% smokers, 16.7% hypertensives and 9.1% diabetics.The averages for age, BMI, TT and DBP were higher in 2013 with respective differences of 4.27 years, 2.23 kg/m2, 8.25 cm and 0.37 mmHgThe prevalence of obesity based on BMI increased from 3.2% in 2002 to 11.5% in 2013 and that based on WC from 16.5 to 33.2%. Predictors of obesity were female sex, age between 30-44 years and high blood pressure.Conclusion The prevalence of obesity is increasing, hence the need for more careful monitoring. Programs to fight against overweight and obesity should be developed in the same way as those for diabetes and high blood pressure

    The Minimum Information about a Molecular Interaction CAusal STatement (MI2CAST).

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    A large variety of molecular interactions occurs between biomolecular components in cells. When a molecular interaction results in a regulatory effect, exerted by one component onto a downstream component, a so-called 'causal interaction' takes place. Causal interactions constitute the building blocks in our understanding of larger regulatory networks in cells. These causal interactions and the biological processes they enable (e.g. gene regulation) need to be described with a careful appreciation of the underlying molecular reactions. A proper description of this information enables archiving, sharing and reuse by humans and for automated computational processing. Various representations of causal relationships between biological components are currently used in a variety of resources. Here, we propose a checklist that accommodates current representations, called the Minimum Information about a Molecular Interaction CAusal STatement (MI2CAST). This checklist defines both the required core information, as well as a comprehensive set of other contextual details valuable to the end user and relevant for reusing and reproducing causal molecular interaction information. The MI2CAST checklist can be used as reporting guidelines when annotating and curating causal statements, while fostering uniformity and interoperability of the data across resources. The checklist together with examples is accessible at https://github.com/MI2CAST/MI2CAST. Supplementary data are available at Bioinformatics online
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