171 research outputs found

    Renormalization Group Running of Lepton Mixing Parameters in See-Saw Models with S4S_4 Flavor Symmetry

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    We study the renormalization group running of the tri-bimaximal mixing predicted by the two typical S4S_4 flavor models at leading order. Although the textures of the mass matrices are completely different, the evolution of neutrino mass and mixing parameters is found to display approximately the same pattern. For both normal hierarchy and inverted hierarchy spectrum, the quantum corrections to both atmospheric and reactor neutrino mixing angles are so small that they can be neglected. The evolution of the solar mixing angle θ12\theta_{12} depends on tan⁥β\tan\beta and neutrino mass spectrum, the deviation from its tri-bimaximal value could be large. Taking into account the renormalization group running effect, the neutrino spectrum is constrained by experimental data on θ12\theta_{12} in addition to the self-consistency conditions of the models, and the inverted hierarchy spectrum is disfavored for large tan⁥β\tan\beta. The evolution of light-neutrino masses is approximately described by a common scaling factor.Comment: 23 pages, 6figure

    The 3-3-1 model with S_4 flavor symmetry

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    We construct a 3-3-1 model based on family symmetry S_4 responsible for the neutrino and quark masses. The tribimaximal neutrino mixing and the diagonal quark mixing have been obtained. The new lepton charge \mathcal{L} related to the ordinary lepton charge L and a SU(3) charge by L=2/\sqrt{3} T_8+\mathcal{L} and the lepton parity P_l=(-)^L known as a residual symmetry of L have been introduced which provide insights in this kind of model. The expected vacuum alignments resulting in potential minimization can origin from appropriate violation terms of S_4 and \mathcal{L}. The smallness of seesaw contributions can be explained from the existence of such terms too. If P_l is not broken by the vacuum values of the scalar fields, there is no mixing between the exotic and the ordinary quarks at the tree level.Comment: 20 pages, revised versio

    NN,N\Delta Couplings and the Quark Model

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    We examine mass-corrected SU(6) symmetry predictions in the quark model relating vector, axial-vector and strong NN and N\Delta couplings, and demonstrate that the experimental N\Delta value is significantly higher than predicted in each case. Nevertheless the Goldberger-Treiman relation is satisfied in both sectors. Possible origins of the discrepancy of the quark model predictions with experiment are discussed.Comment: 22 pg. Latex file, figures available by reques

    Q methodology and rural research

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    Traditionally, rural scholarship has been limited in its methodological approach. This has begun to change in recent years as rural researchers have embraced a range of different methodological tools. The aim of this article is to contribute to greater methodological pluralism in rural sociology by introducing readers to a method of research that is rarely engaged in the field, that is, Q methodology. The article describes the defining features of the approach as well as providing examples of its application to argue that it is a method that offers particular opportunities and synergies for rural social science research

    Development of a versatile laboratory experiment to teach the metabolic transformation of hydrolysis

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    In this paper we describe an easy, reliable, versatile and inexpensive laboratory experiment to teach the metabolic transformation of hydrolysis to Pharmacy students. The experiment does not require the sacrifice of any experimental animal, or any work with organs or tissues, and so can be implemented in a typical university chemistry laboratory. We used acetylsalicylic acid (ASA), hexyl salicylate (HS) and two enzymes, a lipase and an esterase. Since both ASS and HS liberate salicylic acid (SA) upon hydrolysis, students can evaluate the different enzymatic transformations by monitoring the amount of SA liberated. The learning outcomes are an enhanced student understanding of: (1) the process of hydrolysis; (2) the application of enzymatic transformations of molecules from food to xenobiotics; (3) the differences between the general specificity of substrate of both enzymes; (4) the concepts of the lipophilic pocket; (5) the catalytic triad and its regioselectivity in relation to the ester bond. A questionnaire was administered to participating students at three points in time: at the beginning of the module, after enzymatic hydrolysis was taught in class, and after the laboratory experiment. From an analysis of the questionnaire data we conclude that this practical helped Pharmacy students to understand these concepts

    Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging

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    Licopeno Ê um carotenóide com potente atividade antioxidante encontrado em grande quantidade no tomate e usado no combate a diversas doenças como doenças cardiovasculares e diferentes tipos de cânceres, incluindo o câncer de próstata. O objetivo desse trabalho foi desenvolver uma emulsão contendo extrato de licopeno obtido do tomate salada e avaliar a citotoxicidade do extrato, a estabilidade, o comportamento reológico, atividade antioxidante e permeação do fitocosmÊtico. O cosmÊtico foi desenvolvido utilizando fase oleosa contendo derivados de KaritÊ e submetido à avaliação da estabilidade físico-química, espalhabilidade, anålise tÊrmica, comportamento reológico, qualidade microbiológica, citotoxicidade, atividade antioxidante e testes de permeação e retenção cutânea. Os resultados demonstraram que o fitocosmÊtico Ê eståvel, apresenta comportamento reológico desejåvel para uma formulação tópica e Ê um produto promissor para ser utilizado no combate à aceleração do envelhecimento cutâneo.Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging

    Strategies for Controlled Placement of Nanoscale Building Blocks

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    The capability of placing individual nanoscale building blocks on exact substrate locations in a controlled manner is one of the key requirements to realize future electronic, optical, and magnetic devices and sensors that are composed of such blocks. This article reviews some important advances in the strategies for controlled placement of nanoscale building blocks. In particular, we will overview template assisted placement that utilizes physical, molecular, or electrostatic templates, DNA-programmed assembly, placement using dielectrophoresis, approaches for non-close-packed assembly of spherical particles, and recent development of focused placement schemes including electrostatic funneling, focused placement via molecular gradient patterns, electrodynamic focusing of charged aerosols, and others

    Track E Implementation Science, Health Systems and Economics

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138412/1/jia218443.pd
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