Current Renormalisation Constants with an O(a)-improved Fermion Action

Using chiral Ward identities, we determine the renormalisation constants of bilinear quark operators for the Sheikholeslami-Wohlert action lattice at beta=6.2. The results are obtained with a high degree of accuracy. For the vector current renormalisation constant we obtain Z_V=0.817(2)(8), where the first error is statistical and the second is due to mass dependence of Z_V. This is close to the perturbative value of 0.83. For the axial current renormalisation constant we obtain Z_A = 1.045(+10 -14), significantly higher than the value obtained in perturbation theory. This is shown to reduce the difference between lattice estimates and the experimental values for the pseudoscalar meson decay constants, but a significant discrepancy remains. The ratio of pseudoscalar to scalar renormalisation constants, Z_P/Z_S, is less well determined, but seems to be slightly lower than the perturbative value.Comment: 8 pages uuencoded compressed postscript file. Article to be submitted to Phys.Rev.

Model Bond albedos of extrasolar giant planets

The atmospheres of extrasolar giant planets are modeled with various effective temperatures and gravities, with and without clouds. Bond albedos are computed by calculating the ratio of the flux reflected by a planet (integrated over wavelength) to the total stellar flux incident on the planet. This quantity is useful for estimating the effective temperature and evolution of a planet. We find it is sensitive to the stellar type of the primary. For a 5 M_Jup planet the Bond albedo varies from 0.4 to 0.3 to 0.06 as the primary star varies from A5V to G2V to M2V in spectral type. It is relatively insensitive to the effective temperature and gravity for cloud--free planets. Water clouds increase the reflectivity of the planet in the red, which increases the Bond albedo. The Bond albedo increases by an order of magnitude for a 13 M_Jup planet with an M2V primary when water clouds are present. Silicate clouds, on the other hand, can either increase or decrease the Bond albedo, depending on whether there are many small grains (the former) or few large grains (the latter).Comment: 6 pages, 9 figures, uses egs.cls and epsfig.sty, submitted to Physics and Chemistry of the Earth (proceedings of the April 1998 EGS meeting in Nice, France

Quenching Effects in the Hadron Spectrum

Lattice QCD has generated a wealth of data in hadronic physics over the last two decades. Until relatively recently, most of this information has been within the "quenched approximation" where virtual quark--anti-quark pairs are neglected. This review presents a descriptive discussion of the effects of removing this approximation in the calculation of hadronic masses.Comment: To appear in "Lattice Hadron Physics", ed. A.C. Kalloniatis, D.B. Leinweber and A.G. William

Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF

There is considerable interest in the ex vivo propagation of primary human basal epithelial stem/progenitor cells with a view to their use in drug development, toxicity testing and regenerative medicine. These cells can be expanded in co-culture with mitotically inactivated 3T3-J2 murine embryonic feeder cells but, similar to other epithelial cell culture systems employing 3T3-J2 cells, the aspects of cross-talk between 3T3-J2 cells and human airway basal cells that are critical for their expansion remain largely unknown. In this study, we investigated secreted growth factors that are produced by 3T3-J2 cells and act upon primary human airway basal cells. We found robust production of hepatocyte growth factor (HGF) from fibroblast feeder cells following mitotic inactivation. Consistent with the limited cross-species reactivity of murine HGF on the human HGF receptor (MET; HGFR), MET inhibition did not affect proliferative responses in human airway basal cells and HGF could not replace feeder cells in this culture system. However, we found that murine HGF is not completely inactive on human airway epithelial cells or cancer cell lines but stimulates the phosphorylation of GRB2-associated-binding protein 2 (GAB2) and signal transducer and activator of transcription 6 (STAT6). Although HGF induces phosphorylation of STAT6 tyrosine 641 (Y641), there is no subsequent STAT6 nuclear translocation or STAT6-driven transcriptional response. Overall, these findings highlight the relevance of cross-species protein interactions between murine feeder cells and human epithelial cells in 3T3-J2 co-culture and demonstrate that STAT6 phosphorylation occurs in response to MET activation in epithelial cells. However, STAT6 nuclear translocation does not occur in response to HGF, precluding the transcriptional activity of STAT6

Modelling boreholes in complex heterogeneous aquifers

Reliable estimates of the sustainable yield of supply boreholes are critical to ensure that groundwater resources are managed sustainably. Sustainable yields are dependent on the pumped groundwater level in a borehole, how this relates to vertical aquifer heterogeneity, and features of the borehole itself. This paper presents a 3D radial flow model (SPIDERR), based on the Darcy-Forchheimer equation, for simulating the groundwater level response in supply boreholes in unconfined, heterogeneous aquifers. The model provides a tool for investigating the causes of non-linear behaviour in abstraction boreholes, which can have a significant impact on sustainable yields. This is demonstrated by simulating a variable-rate pumping test in a Chalk abstraction borehole. The application suggests the non-linear response to pumping is due to a combination of factors: a reduction in well storage with depth due to changes in the borehole diameter, a reduction in hydraulic conductivity with depth, and non-Darcian flow

An integrated modelling approach for assessing the effect of multiscale complexity on groundwater source yields

A new multi-scale groundwater modelling methodology is presented to simulate pumped water levels in abstraction boreholes within regional groundwater models, providing a robust tool for assessing the sustainable yield of supply boreholes and improving our understanding of groundwater availability during drought. A 3D borehole-scale model, which solves the Darcy-Forchheimer equation in cylindrical co-ordinates to simulate both linear and non-linear radial flow to a borehole in a heterogeneous aquifer, is embedded within a Cartesian grid, using a hybrid radial-Cartesian finite difference method. The local-scale model is coupled to a regional groundwater model, ZOOMQ3D, using the OpenMI model linkage software, providing a flexible and efficient tool for assessing the behaviour of a groundwater source within its regional hydrogeological context during historic droughts and under climate change. The advantages of the new method are demonstrated through application to a Chalk supply borehole in the UK

A Bayesian Approach to Calibrating Period-Luminosity Relations of RR Lyrae Stars in the Mid-Infrared

A Bayesian approach to calibrating period-luminosity (PL) relations has substantial benefits over generic least-squares fits. In particular, the Bayesian approach takes into account the full prior distribution of the model parameters, such as the a priori distances, and refits these parameters as part of the process of settling on the most highly-constrained final fit. Additionally, the Bayesian approach can naturally ingest data from multiple wavebands and simultaneously fit the parameters of PL relations for each waveband in a procedure that constrains the parameter posterior distributions so as to minimize the scatter of the final fits appropriately in all wavebands. Here we describe the generalized approach to Bayesian model fitting and then specialize to a detailed description of applying Bayesian linear model fitting to the mid-infrared PL relations of RR Lyrae variable stars. For this example application we quantify the improvement afforded by using a Bayesian model fit. We also compare distances previously predicted in our example application to recently published parallax distances measured with the Hubble Space Telescope and find their agreement to be a vindication of our methodology. Our intent with this article is to spread awareness of the benefits and applicability of this Bayesian approach and encourage future PL relation investigations to consider employing this powerful analysis method.Comment: 6 pages, 1 figure. Accepted for publication in Astrophysics & Space Science. Following a presentation at the conference The Fundamental Cosmic Distance Scale: State of the Art and the Gaia Perspective, Naples, May 201

Effect of altering the type of dietary carbohydrate early postpartum on reproductive performance and milk production in pasture-grazed dairy cows

peer-reviewedABSTRACTThe objective of this study was to assess the effect of increasing dietary starch for approximately 30 d postpartum on reproduction outcomes in pasture-grazed, seasonal-calving dairy cows. Cows (n = 948) from 3 commercial herds were blocked by age (2, 3, and >3 yr), breed, and expected calving date and randomly assigned to 1 of 2 postpartum treatment groups: high starch (34.7 ± 1.9% nonstructural carbohydrate; mean ± SD) or low starch (22.5 ± 0.4% nonstructural carbohydrate). The high-starch group in all 3 farms received 4.0 to 4.5 kg/d of a 75:25 cracked corn:barley grain mixture in the dairy parlor, split evenly between the morning and afternoon milkings. The low-starch cows received 5.0 to 5.5 kg/d of a 50:50 mixture of palm kernel meal:soy hulls (herds 1 and 3) fed in the parlor; low-starch cows in the remaining herd (herd 2) did not receive a concentrate feed. Cows were cograzed on ryegrass–white clover dominant pastures and were offered corn silage (herds 1 and 3) and canola, corn distillers grain, and palm kernel meal (herd 1) throughout the study. At 1 mo before the start of the seasonal breeding period, the high-starch supplement was removed, and within each herd treatment groups were managed similarly through breeding. Presence of purulent vaginal discharge was assessed at 28 DIM, and tail paint was assessed weekly from 2 to 6 wk postpartum for signs of estrus. The interval to first observed estrus was unaffected by treatment (32.7 vs. 33.5 ± 2 d for high and low starch, respectively), but there were tendencies for a herd × treatment interaction for proportion of cows pregnant to first service and for pregnancy within 6 wk. This interaction was significant for the proportion of cows finally pregnant; a lower proportion of high-starch cows were pregnant to first service, pregnant by 6 wk, and pregnant by the end of the seasonal breeding period in herd 1, but diet did not affect these outcomes in the other herds. Our results do not support a positive effect on reproduction from increasing dietary starch in seasonally bred grazing dairy cows. However, the interactions indicate variability in the herd response to dietary starch early postpartum and imply that pregnancy rate could potentially be compromised through the provision of starch to grazing dairy cows in early lactation (i.e., prebreeding). The experiment was not designed to define the reasons for these interactions, but differences should be considered in future research on the subject

The Leptonic Decay Constants of Qˉq\bar{Q}q Mesons and the Lattice Resolution

We present a high statistics study of the leptonic decay constant $f_P$ of heavy pseudoscalar mesons using propagating heavy Wilson quarks within the quenched approximation, on lattices covering sizes from about 0.7~fm to 2~fm. Varying $\beta$ between 5.74 and 6.26 we observe a sizeable $a$ dependence of $f_P$ when one uses the quark field normalization that was suggested by Kronfeld and Mackenzie, compared with the weaker dependence observed for the standard relativistic norm. The two schemes come into agreement when one extrapolates to $a \rightarrow 0$. The extrapolations needed to reach the continuum quantity $f_B$ introduce large errors and lead to the value $f_B=0.18(5)$~GeV in the quenched approximation. This suggests that much more effort will be needed to obtain an accurate lattice prediction for $f_B$.Comment: 11 pages Latex + 5 tables + 8 postscript figures, unix shell archive, DESY preprint DESY 93-17