Evaluation in Europe: An Overview

The article presents an overview of evaluation in Europe, highlighting the activities and publications of the European Evaluation Society

An Update on Evaluation in Europe

Details of events and news items listed below can be found on the corresponding Web sites

Evaluation: The International Journal of Theory, Research and Practice

The first 2005 issue of Evaluation (Volume 11(1), January 2005) begins with two contributions to A Visit to the World of Practice, both of which focus on results-based evaluation and impact assessment within the context of the Millennium Development Goals (MDGs). Please visit http://ddp-ext.worldbank.org/ext/MDG/-home.do for information on the MDGs

Evaluation: The International Journal of Theory, Research and Practice (2003-2004)

This article analyzes four issues of the journal Evaluation regarding whether articles published are specific to theory, research, or practice.

Lithium-induced EEG changes in patients with affective disorders

In 12 patients with affective disorders (ICD-10: F31, F32, F33), EEGs were recorded before and after 4.4 months of lithium treatment. Effects of lithium on the EEG were analyzed by power spectral analysis controlled for vigilance. We found (1) an increase in relative power in both delta and theta band which was related to the lithium plasma level, (2) a decrease in relative alpha power especially at occipital leads and (3) a reduction of the dominant alpha frequency. The changes in relative power were more pronounced in the right hemisphere, which is in contrast to the hypothesis of a site-specific localization of lithium effects only in left anterior regions. Copyright (C) 2000 S. Karger AG,Basel

Climate neutral truck traffic due to algae-based fuels? TAB-Fokus

Biofuels produced from algae represent an innovative approach with regard to the renewable and climatefriendly energy supply of the truck fleet which currently is predominantly powered by diesel fuel. Algae have a significantly higher productivity than conventional energy crops and can help prevent land use conflicts with food production or nature conservation. Research on the production of algae-based fuels is being conducted worldwide. So far, however, it has not been possible to produce algae-based fuel in an energy-efficient and economically viable way on a scale that is relevant for road haulage. Options for improving competitiveness can be found in optimising the selection and cultivation of algae and the utilisation of algae in so-called biorefineries, where various algae-based resources and products are produced simultaneously

Robustness and timing of cellular differentiation through population-based symmetry breaking

During mammalian development, cell types expressing mutually exclusive genetic markers are differentiated from a multilineage primed state. These observations have invoked single-cell multistability view as the dynamical basis of differentiation. However, the robust regulative nature of mammalian development is not captured therein. Considering the well-established role of cell-cell communication in this process, we propose a fundamentally different dynamical treatment in which cellular identities emerge and are maintained on population level, as a novel unique solution of the coupled system. Subcritical system’s organization here enables symmetry-breaking to be triggered by cell number increase in a timed, self-organized manner. Robust cell type proportions are thereby an inherent feature of the resulting inhomogeneous solution. This framework is generic, as exemplified for early embryogenesis and neurogenesis cases. Distinct from mechanisms that rely on pre-existing asymmetries, we thus demonstrate that robustness and accuracy necessarily emerge from the cooperative behaviour of growing cell populations during development

Nogo-a regulates neural precursor migration in the embryonic mouse cortex

Although Nogo-A has been intensively studied for its inhibitory effect on axonal regeneration in the adult central nervous system, little is known about its function during brain development. In the embryonic mouse cortex, Nogo-A is expressed by radial precursor/glial cells and by tangentially migrating as well as postmigratory neurons. We studied radially migrating neuroblasts in wild-type and Nogo-A knockout (KO) mouse embryos. In vitro analysis showed that Nogo-A and its receptor components NgR, Lingo-1, TROY, and p75 are expressed in cells emigrating from embryonic forebrain-derived neurospheres. Live imaging revealed an increased cell motility when Nogo-A was knocked out or blocked with antibodies. Antibodies blocking NgR or Lingo-1 showed the same motility-enhancing effect supporting a direct role of surface Nogo-A on migration. Bromodeoxyuridine (BrdU) labeling of embryonic day (E)15.5 embryos demonstrated that Nogo-A influences the radial migration of neuronal precursors. At E17.5, the normal transient accumulation of radially migrating precursors within the subventricular zone was not detectable in the Nogo-A KO mouse cortex. At E19, migration to the upper cortical layers was disturbed. These findings suggest that Nogo-A and its receptor complex play a role in the interplay of adhesive and repulsive cell interactions in radial migration during cortical developmen

Tailoring the frictional properties of granular media

A method of modifying the roughness of soda-lime glass spheres is presented, with the purpose of tuning inter-particle friction. The effect of chemical etching on the surface topography and the bulk frictional properties of grains is systematically investigated. The surface roughness of the grains is measured using white light interferometry and characterised by the lateral and vertical roughness length scales. The underwater angle of repose is measured to characterise the bulk frictional behaviour. We observe that the co-efficient of friction depends on the vertical roughness length scale. We also demonstrate a bulk surface roughness measurement using a carbonated soft drink.Comment: 10 pages, 17 figures, submitted to Phys. Rev.