1,867 research outputs found

    The Quantum Cyclic Rotation Gate

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    A circular shift operator (or cyclic rotation gate) ROTk applies a rightward (or leftward) shift of k positions to a register of n qubits so that the element at position x is moved to position (x + k) mod n. While it is known that there exists a quantum rotation operator that can be implemented in O(log(n))-time, through the repeated parallel application of the elementary Swap operators, there is no systematic procedure that concretely constructs the quantum operator ROT for variable size n of the quantum register and a variable parameter k. We show a concrete implementation of the cyclic rotation operator (denoted ROT) in a quantum circuit model of computation. The depth of the obtained circuit implementing the cyclic rotation operator is upper-bounded by log n; therefore, the operator ROTk can be implemented in O(log(n))-time. When the parameter k dictating the magnitude of the rotation is a power of 2, namely when k = 2m for some 2, the depth of the circuit is exactly log(n) - log(k)

    Active primate simulator Final report

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    Systems engineering data and design specifications for Biosatellite active primate simulato

    Sustainable gardens: an evaluation tool for management and planning strategies.

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    An evaluation tool was defined in order to manage gardens considering the six main directives of sustainability, from plant collections to public awareness and fruition

    Seed morphology and seed coat structure in Mediterranean plants: implication for evolution, taxonomy and germinative performance

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    A better understanding of morphological, ultra-structural and anatomical seed coat characteristics can contribute to explain and predict seed performance under certain environmental conditions and select the most suitable treatments promoting seed germination. The Seed Banks at the Botanic Gardens of Catania and Palermo (Sicily) are particularly involved in research studies aimed to detect and describe macro- and micro-morphological features of seeds from different plant families and genera, using both light and scanning electron microscopy. These studies mainly aim to 1) recognize and compare inter- and intra-specific variation of seed coat traits, with particular attention on rare and threatened species; 2) evaluate the usefulness of these traits in taxonomic and phylogenetic studies; 3) establish correlations between seed coat structures and seed germination; 4) understand the seed coat adaptive potential and sensitivity to particular ecological conditions and changing environments

    Optical mapping of neuronal activity during seizures in zebrafish

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    Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a better understanding of the mechanisms underlying this pathology and improve our approaches to the development of new drugs. Recently, zebrafish has become an important model for studying epilepsy both in basic research and in drug discovery. Here, we employed a transgenic line with pan-neuronal expression of the genetically-encoded calcium indicator GCaMP6s to measure neuronal activity in zebrafish larvae during seizures induced by pentylenetretrazole (PTZ). With this approach, we mapped neuronal activity in different areas of the larval brain, demonstrating the high sensitivity of this method to different levels of alteration, as induced by increasing PTZ concentrations, and the rescuing effect of an anti-epileptic drug. We also present simultaneous measurements of brain and locomotor activity, as well as a high-throughput assay, demonstrating that GCaMP measurements can complement behavioural assays for the detection of subclinical epileptic seizures, thus enabling future investigations on human hypomorphic mutations and more effective drug screening methods. Notably, the methodology described here can be easily applied to the study of many human neuropathologies modelled in zebrafish, allowing a simple and yet detailed investigation of brain activity alterations associated with the pathological phenotype

    Preterm birth after loop electrosurgical excision procedure (LEEP). how cone features and microbiota could influence the pregnancy outcome

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    OBJECTIVE: In the last years, the mean age of women who underwent cervical treatment for high-grade cervical intraepithelial neoplasia (CIN 2-3) is similar to the age of women having their first pregnancy. The aim of this study was to evaluate the risk of preterm birth in subsequent pregnancies after loop electrosurgical excision procedure (LEEP). PATIENTS AND METHODS: From January 2013 to January 2016 the study identified a total of 1435 women, nulliparous, who underwent LEEP for CIN 2-3, and who wished to have their first pregnancy. Before surgery, the lengths of the cervix were calculated by transvaginal sonography. After the treatment, the dimension of the removed tissue was evaluated. During the pregnancy, all women carried out periodic transvaginal sonography and vaginal-cervical swabs. RESULTS: The average age of patients was 31.96±5.24 years; the interval between the surgical procedure and pregnancy was 12.04±4.67 months; the gestational age at births was 37.53±2.91 weeks. The first vaginal and cervical swab performed during pregnancy was negative in 81.8% of patients. The most prevalent infections were related to C. Albicans, G. Vaginalis, and Group B Streptococcus (GBS). The rate of preterm delivery was significantly higher in women with a minor cervical length. CONCLUSIONS: The length and the volume of cervical tissue excised have been shown to be directly related to the risk for preterm birth. Furthermore, vaginal infections and their persistence during pregnancy in women with a history of LEEP may be associated with an increased risk for preterm birth, compared with women with no history of LEEP
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