A Catalog of Very Isolated Galaxies from the SDSS Data Release 1

We present a new catalog of isolated galaxies obtained through an automated systematic search. These 2980 isolated galaxies were found in approximately 2099 sq deg of sky in the Sloan Digital Sky Survey Data Release 1 (SDSS DR1) photometry. The selection algorithm, implementing a variation on the criteria developed by Karachentseva in 1973, proved to be very efficient and fast. This catalog will be useful for studies of the general galaxy characteristics. Here we report on our results.Comment: 67 pages, which includes 14 figures. Accepted for publication by A

The X-ray Position and Optical Counterpart of the Accretion-Powered Millisecond Pulsar XTE J1814-338

We report the precise optical and X-ray localization of the 3.2 ms accretion-powered X-ray pulsar XTE J1814-338 with data from the Chandra X-Ray Observatory as well as optical observations conducted during the 2003 June discovery outburst. Optical imaging of the field during the outburst of this soft X-ray transient reveals an R = 18 star at the X-ray position. This star is absent (R > 20) from an archival 1989 image of the field and brightened during the 2003 outburst, and we therefore identify it as the optical counterpart of XTE J1814-338. The best source position derived from optical astrometry is R.A. = 18h13m39.s04, Dec.= -33d46m22.3s (J2000). The featureless X-ray spectrum of the pulsar in outburst is best fit by an absorbed power-law (with photon index = 1.41 +- 0.06) plus blackbody (with kT = 0.95 +- 0.13 keV) model, where the blackbody component contributes approximately 10% of the source flux. The optical broad-band spectrum shows evidence for an excess of infrared emission with respect to an X-ray heated accretion disk model, suggesting a significant contribution from the secondary or from a synchrotron-emitting region. A follow-up observation performed when XTE J1814-338 was in quiescence reveals no counterpart to a limiting magnitude of R = 23.3. This suggests that the secondary is an M3 V or later-type star, and therefore very unlikely to be responsible for the soft excess, making synchroton emission a more reasonable candidate.Comment: Accepted for publication in ApJ. 6 pages; 3 figure

An Optical Study of BG Geminorum: An Ellipsoidal Binary with an Unseen Primar Star

We describe optical photometric and spectroscopic observations of the bright variable BG Geminorum. Optical photometry shows a pronounced ellipsoidal variation of the K0 I secondary, with amplitudes of ~0.5 mag at VRI and a period of 91.645 days. A deep primary eclipse is visible for wavelengths < 4400A; a shallower secondary eclipse is present at longer wavelengths. Eclipse timings and the radial velocity curve of the K0 secondary star indicate an interacting binary where a lobe-filling secondary, M_2 ~ 0.5 Msun, transfers material into a extended disk around a massive primary, M_1 ~ 4.5 Msun. The primary star is either an early B-type star or a black hole. If it did contain a black hole, BG Gem would be the longest period black hole binary known by a factor of 10, as well as the only eclipsing black hole binary system.Comment: 27 pages, includes 8 figures and 5 tables, accepted to A

Chandra Phase-Resolved Spectroscopy of the Crab Pulsar

We present the first phase-resolved study of the X-ray spectral properties of the Crab Pulsar that covers all pulse phases. The superb angular resolution of the Chandra X-ray Observatory enables distinguishing the pulsar from the surrounding nebulosity, even at pulse minimum. Analysis of the pulse-averaged spectrum measures interstellar X-ray extinction due primarily to photoelectric absorption and secondarily to scattering by dust grains in the direction of the Crab Nebula. We confirm previous findings that the line-of-sight to the Crab is underabundant in oxygen, although more-so than recently measured. Using the abundances and cross sections from Wilms, Allen & McCray (2000) we find [O/H] = (3.33 +/-0.25) x 10**-4. Analysis of the spectrum as a function of pulse phase measures the low-energy X-ray spectral index even at pulse minimum -- albeit with large statistical uncertainty -- and we find marginal evidence for variations of the spectral index. The data are also used to set a new (3-sigma) upper limit to the temperature of the neutron star of log T(infinity) < 6.30.Comment: 20 Pages including 7 figures. Accepted for publication in the Astrophysical Journa

Drama-based education to motivate participation in substance abuse prevention

BACKGROUND: The substance abuse prevention goal of the theatre production "TUNNELS" was to provide community education on substance abuse to an audience in Durham, NC and surrounding communities. The education effort intended to increase awareness and understanding of the risk and protective factors associated with alcohol and other drug use, and to promote pro-active behaviors in substance abuse prevention within the adult community. It was hypothesized that community-based education via drama would change attitudes toward alcohol and substance abuse, and increase participation in family and community activities aimed at substance abuse prevention. METHODS: A focus group comprised of educators, substance abuse researchers and local substance abuse counselors developed "life stories" of users of alcohol and other drugs and a local playwright incorporated these and other experiences into a series of six vignettes. The production was publicized throughout the Durham area, and 700 adults attending the play signed a consent form and completed the pre-play survey. The participant pool was restricted to those adults who completed both the time-1 and time-2 surveys and resided within Durham and surrounding communities. Paired comparisons of mean responses were analyzed using a paired sample two-tailed t-test. A telephone survey three months after the play assessed attitudes toward substance abuse as a disease, and whether the respondents had increased their participation in prevention activities including discussions of the play with others. RESULTS: Viewing the play increased the knowledge base of participants regarding substance abuse as a disease, even though the audience demonstrated an appreciation of risk and protective factors prior to attending the performance. In the pre-play survey, participants indicated a strong opinion that parental involvement in teen life was important, and therefore this was not increased as a result of viewing the play. It was found that the drama increased intent to participate in substance abuse prevention activities at home and in the community. Follow-up surveys performed three months after the performance indicated that participants had discussed the play with others and had increased their participation in substance abuse prevention activities, particularly regarding donations of money. CONCLUSION: Drama incorporates a component of emotional response to the informational content, and the combination of emotion and information works together to promote individual intentions to become more involved in family and community prevention activities. This study demonstrates the efficacy of drama as a mechanism to educate and motivate. Support for this mechanism is warranted at the level of state, local community, school district, and faith-based and community organizations

Unraveling the Geometry of the Crab Nebula's "Inner Ring"

Chandra images of the Crab Nebula resolve the detailed structure of its "inner ring", possibly a termination shock where pulsar-accelerated relativistic particles begin to emit X radiation. Analysis of these images finds that the center of the ellipse-presumably a circular ring in projection-lies about 0.9" (10 light-days at 2 kpc) from the pulsar's image, at a position angle of about 300{\deg} (East of North). This analysis also measures properties of the ellipse: The position angle of the semi-major axis is about 210{\deg} (East of North); the aspect ratio, 0.49. In a simple-albeit, not unique-de-projection of the observed geometry, a circular ring is centered on the axis of symmetry of the pulsar wind nebula. This ring is not equatorial but rather lies near +4.5{\deg} latitude in pulsar-centered coordinates. Alternative geometries are briefly discussed.Comment: 12 pages, f figures, submitted to the Astrophysical Journa

New Observations of the Crab Nebula and Pulsar

We present a phase-resolved study of the X-ray spectrum of the Crab Pulsar, using data obtained in a special mode with the Chandra X-ray Observatory. The superb angular resolution easily enables discerning the Pulsar from the surrounding nebulosity, even at pulse minimum. We find that the Pulsar's X-ray spectral index varies sinusoidally with phase---except over the same phase range for which rather abrupt changes in optical polarization magnitude and position angle have been reported. In addition, we use the X-ray data to constrain the surface temperature for various neutron-star equations of state and atmospheres. Finally, we present new data on dynamical variations of structure within the Nebula

Merging Galaxies in the SDSS EDR

We present a new catalog of merging galaxies obtained through an automated systematic search routine. The 1479 new pairs of merging galaxies were found in approximately 462 sq deg of the Sloan Digital Sky Survey Early Data Release (SDSS EDR; Stoughton et al. 2002) photometric data, and the pair catalog is complete for galaxies in the magnitude range 16.0 <= g* <= 20. The selection algorithm, implementing a variation on the original Karachentsev (1972) criteria, proved to be very efficient and fast. Merging galaxies were selected such that the inter-galaxy separations were less than the sum of the component galaxies' radii. We discuss the characteristics of the sample in terms of completeness, pair separation, and the Holmberg effect. We also present an online atlas of images for the SDSS EDR pairs obtained using the corrected frames from the SDSS EDR database. The atlas images also include the relevant data for each pair member. This catalog will be useful for conducting studies of the general characteristics of merging galaxies, their environments, and their component galaxies. The redshifts for a subset of the interacting and merging galaxies and the distribution of angular sizes for these systems indicate the SDSS provides a much deeper sample than almost any other wide-area catalog to date.Comment: 58 pages, which includes 15 figures and 6 tables. Figures 2, 8, 9, 10, 11, 13, and 14 are provided as JPEG files. For online atlas, see http://home.fnal.gov/~sallam/MergePair/ . Accepted for publication in A

Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases.

PurposeTo describe examples of missed pathogenic variants on whole-exome sequencing (WES) and the importance of deep phenotyping for further diagnostic testing.MethodsGuided by phenotypic information, three children with negative WES underwent targeted single-gene testing.ResultsIndividual 1 had a clinical diagnosis consistent with infantile systemic hyalinosis, although WES and a next-generation sequencing (NGS)-based ANTXR2 test were negative. Sanger sequencing of ANTXR2 revealed a homozygous single base pair insertion, previously missed by the WES variant caller software. Individual 2 had neurodevelopmental regression and cerebellar atrophy, with no diagnosis on WES. New clinical findings prompted Sanger sequencing and copy number testing of PLA2G6. A novel homozygous deletion of the noncoding exon 1 (not included in the WES capture kit) was detected, with extension into the promoter, confirming the clinical suspicion of infantile neuroaxonal dystrophy. Individual 3 had progressive ataxia, spasticity, and magnetic resonance image changes of vanishing white matter leukoencephalopathy. An NGS leukodystrophy gene panel and WES showed a heterozygous pathogenic variant in EIF2B5; no deletions/duplications were detected. Sanger sequencing of EIF2B5 showed a frameshift indel, probably missed owing to failure of alignment.ConclusionThese cases illustrate potential pitfalls of WES/NGS testing and the importance of phenotype-guided molecular testing in yielding diagnoses