Effects of a Novel Dental Gel on Plaque and Gingivitis: A Comparative Study.

ObjectivesThe goal of this prospective, randomized, controlled, double-blinded study was to evaluate the effects of a novel dental gel on plaque and gingival health. The dental gel was designed to (1) break up and prevent re-accumulation of microbial biofilm, and (2) inhibit metal mediated inflammation.Materials and methodsTwenty-five subjects with moderate gingival inflammation (Löe and Silness Gingival Index ≥2) and pocket depths <4 were randomly assigned to brush twice daily for 21 days with the test or the control dental gel. On Days 0, 7, 14 and 21, plaque levels (Quigley-Hein, Turesky Modification Plaque Index), gingival inflammation (Löe and Silness Gingival Index) and gingival bleeding (modified Sulcus Bleeding Index) were determined by one blinded, investigator using a pressure sensitive probe.ResultsAfter 3 weeks, all 3 clinical indices were significantly improved in both groups (P<0.05) and significantly lower in the test group (P<0.05).ConclusionThe novel dental gel formulation was provided effective plaque control and reduced gingival inflammation.Clinical relevanceA novel dentifrice formulation may be an effective tool for plaque removal and maintaining gingival health

The Nature of Optical Features in the Inner Region of the 3C48 Host Galaxy

The well-known quasar 3C48 is the most powerful compact steep-spectrum radio-loud QSO at low redshifts. It also has two unusual optical features within the radius of the radio jet (~1"): (1) an anomalous, high-velocity narrow-line component, having several times as much flux as does the narrow-line component coinciding with the broad-line redshift; and (2) a bright continuum peak (3C48A) ~1" northeast of the quasar. Both of these optical features have been conjectured to be related to the radio jet. Here we explore these suggestions. We have obtained Gemini North GMOS integral-field-unit (IFU) spectroscopy of the central region around 3C48. We use the unique features of the IFU data to remove unresolved emission at the position of the quasar. The resolved emission at the wavelength of the high-velocity component is peaked <~0.25" north of the quasar, at virtually the same position angle as the base of the radio jet. These observations appear to confirm that this high-velocity gas is connected with the radio jet. However, most of the emission comes from a region where the jet is still well collimated, rather than from the regions where the radio maps indicate strong interaction with an external medium. We also present the results of HST STIS spectroscopy of 3C48A. We show that 3C48A is dominated by stars with a luminosity-weighted age of ~1.4 X 10^8 years, substantially older than any reasonable estimate for the age of the radio source. Our IFU data indicate a similar age. Thus, 3C48A almost certainly cannot be attributed to jet-induced star formation. The host galaxy of 3C48 is clearly the result of a merger, and 3C48A seems much more likely to be the distorted nucleus of the merging partner, in which star formation was induced during the previous close passage.Comment: 10 pages, accepted by The Astrophysical Journa

Pearling: stroke segmentation with crusted pearl strings

We introduce a novel segmentation technique, called Pearling, for the semi-automatic extraction of idealized models of networks of strokes (variable width curves) in images. These networks may for example represent roads in an aerial photograph, vessels in a medical scan, or strokes in a drawing. The operator seeds the process by selecting representative areas of good (stroke interior) and bad colors. Then, the operator may either provide a rough trace through a particular path in the stroke graph or simply pick a starting point (seed) on a stroke and a direction of growth. Pearling computes in realtime the centerlines of the strokes, the bifurcations, and the thickness function along each stroke, hence producing a purified medial axis transform of a desired portion of the stroke graph. No prior segmentation or thresholding is required. Simple gestures may be used to trim or extend the selection or to add branches. The realtime performance and reliability of Pearling results from a novel disk-sampling approach, which traces the strokes by optimizing the positions and radii of a discrete series of disks (pearls) along the stroke. A continuous model is defined through subdivision. By design, the idealized pearl string model is slightly wider than necessary to ensure that it contains the stroke boundary. A narrower core model that fits inside the stroke is computed simultaneously. The difference between the pearl string and its core contains the boundary of the stroke and may be used to capture, compress, visualize, or analyze the raw image data along the stroke boundary

Dictionary Learning and Sparse Coding-based Denoising for High-Resolution Task Functional Connectivity MRI Analysis

We propose a novel denoising framework for task functional Magnetic Resonance Imaging (tfMRI) data to delineate the high-resolution spatial pattern of the brain functional connectivity via dictionary learning and sparse coding (DLSC). In order to address the limitations of the unsupervised DLSC-based fMRI studies, we utilize the prior knowledge of task paradigm in the learning step to train a data-driven dictionary and to model the sparse representation. We apply the proposed DLSC-based method to Human Connectome Project (HCP) motor tfMRI dataset. Studies on the functional connectivity of cerebrocerebellar circuits in somatomotor networks show that the DLSC-based denoising framework can significantly improve the prominent connectivity patterns, in comparison to the temporal non-local means (tNLM)-based denoising method as well as the case without denoising, which is consistent and neuroscientifically meaningful within motor area. The promising results show that the proposed method can provide an important foundation for the high-resolution functional connectivity analysis, and provide a better approach for fMRI preprocessing.Comment: 8 pages, 3 figures, MLMI201

Hot gas and dust in a protostellar cluster near W3(OH

We used the IRAM Interferometer to obtain sub-arcsecond resolution observations of the high-mass star-forming region W3(OH) and its surroundings at a frequency of 220 GHz. With the improved angular resolution, we distinguish 3 peaks in the thermal dust continuum emission originating from the hot core region about 6 arcsec (0.06 pc) east of W3(OH). The dust emission peaks are coincident with known radio continuum sources, one of which is of non-thermal nature. The latter source is also at the center of expansion of a powerful bipolar outflow observed in water maser emission. We determine the hot core mass to be 15 solar masses based on the integrated dust continuum emission. Simultaneously many molecular lines are detected allowing the analysis of the temperature structure and the distribution of complex organic molecules in the hot core. From HNCO lines, spanning a wide range of excitation, two 200 K temperature peaks are found coincident with dust continuum emission peaks suggesting embedded heating sources within them.Comment: 12 pages, 3 figure

A multi-particle model of the 3C 48 host

The first successful multi-particle model for the host of the well-known quasi-stellar object (QSO) 3C 48 is reported. It shows that the morphology and the stellar velocity field of the 3C 48 host can be reproduced by the merger of two disk galaxies. The conditions of the interaction are similar to those used for interpreting the appearance of the ''Antennae'' (NGC 4038/39) but seen from a different viewing angle. The model supports the controversial hypothesis that 3C 48A is the second nucleus of a merging galaxy, and it suggests a simple solution for the problem of the missing counter tidal tail.Comment: 5 pages, 5 figures, accepted for publication in A&

Full-Polarization Observations of OH Masers in Massive Star-Forming Regions: I. Data

We present full-polarization VLBA maps of the ground-state, main-line, 2 Pi 3/2, J = 3/2 OH masers in 18 Galactic massive star-forming regions. This is the first large polarization survey of interstellar hydroxyl masers at VLBI resolution. A total of 184 Zeeman pairs are identified, and the corresponding magnetic field strengths are indicated. We also present spectra of the NH3 emission or absorption in these star-forming regions. Analysis of these data will be presented in a companion paper.Comment: 111 pages, including 42 figures and 21 tables, to appear in ApJ

Neutron-induced background in the CONUS experiment

CONUS is a novel experiment aiming at detecting elastic neutrino nucleus scattering in the fully coherent regime using high-purity Germanium (Ge) detectors and a reactor as antineutrino ($\bar\nu$) source. The detector setup is installed at the commercial nuclear power plant in Brokdorf, Germany, at a very small distance to the reactor core in order to guarantee a high flux of more than 10$^{13}\bar\nu$/(s$\cdot$cm$^2$). For the experiment, a good understanding of neutron-induced background events is required, as the neutron recoil signals can mimic the predicted neutrino interactions. Especially neutron-induced events correlated with the thermal power generation are troublesome for CONUS. On-site measurements revealed the presence of a thermal power correlated, highly thermalized neutron field with a fluence rate of (745$\pm$30)cm$^{-2}$d$^{-1}$. These neutrons that are produced by nuclear fission inside the reactor core, are reduced by a factor of $\sim$10$^{20}$ on their way to the CONUS shield. With a high-purity Ge detector without shield the $\gamma$-ray background was examined including highly thermal power correlated $^{16}$N decay products as well as $\gamma$-lines from neutron capture. Using the measured neutron spectrum as input, it was shown, with the help of Monte Carlo simulations, that the thermal power correlated field is successfully mitigated by the installed CONUS shield. The reactor-induced background contribution in the region of interest is exceeded by the expected signal by at least one order of magnitude assuming a realistic ionization quenching factor of 0.2.Comment: 28 pages, 28 figure

Radio Continuum and Recombination Line Study of UC HII Regions with Extended Envelopes

We have carried out 21 cm radio continuum observations of 16 UC HII regions using the VLA (D-array) in search of associated extended emission. We have also observed H76$_\alpha$ recombination line towards all the sources and He76$_\alpha$ line at the positions with strong H76$_\alpha$ line emission. The UC HII regions have simple morphologies and large (>10) ratios of single-dish to VLA fluxes. Extended emission was detected towards all the sources. The extended emission consists of one to several compact components and a diffuse extended envelope. All the UC HII regions but two are located in the compact components, where the UC HII regions always correspond to their peaks. The compact components with UC HII regions are usually smaller and denser than those without UC HII regions. Our recombination line observations indicate that the ultracompact, compact, and extended components are physically associated. The UC HII regions and their associated compact components are likely to be ionized by the same sources on the basis of the morphological relations mentioned above. This suggests that almost all of the observed UC HII regions are not `real' UC HII regions and that their actual ages are much greater than their dynamical age (<10000 yr). We find that most of simple UC HII regions previously known have large ratios of single-dish to VLA fluxes, similar to our sources. Therefore, the `age problem' of UC HII regions does not seem to be as serious as earlier studies argued. We present a simple model that explains extended emission around UC HII regions. Some individual sources are discussed.Comment: 29 pages, 28 postscript figures, Accepted for publication in Ap