226 research outputs found
Coulomb Drag in the Exciton Regime in Electron-Hole Bilayers
We report electrical transport measurements on GaAs/AlGaAs based
electron-hole bilayers. These systems are expected to make a transition from a
pair of weakly coupled two-dimensional systems to a strongly coupled exciton
system as the barrier between the layers is reduced. Once excitons form,
phenomena such as Bose-Einstein condensation of excitons could be observed. In
our devices, electrons and holes are confined in double quantum wells, and
carriers in the devices are induced with top and bottom gates leading to
variable density in each layer. Separate contact to each layer allows Coulomb
drag transport measurements where current is driven in one layer while voltage
is measured in the other. Coulomb drag is sensitive to interlayer coupling and
has been predicted to provide a strong signature of exciton condensation. Drag
measurement on EHBLs with a 30 nm barrier are consistent with drag between two
weakly coupled 2D Fermi systems where the drag decreases as the temperature is
reduced. When the barrier is reduced to 20 nm, we observe a consistent increase
in the drag resistance as the temperature is reduced. These results indicate
the onset of a much stronger coupling between the electrons and holes which
leads to exciton formation and possibly phenomena related to exciton
condensation.Comment: 12 pages, 3 figure
Theory of sound attenuation in glasses: The role of thermal vibrations
Sound attenuation and internal friction coefficients are calculated for a
realistic model of amorphous silicon. It is found that, contrary to previous
views, thermal vibrations can induce sound attenuation at ultrasonic and
hypersonic frequencies that is of the same order or even larger than in
crystals. The reason is the internal-strain induced anomalously large
Gr\"uneisen parameters of the low-frequency resonant modes.Comment: 8 pages, 3 figures; to appear in PR
Thermal Properties of Graphene, Carbon Nanotubes and Nanostructured Carbon Materials
Recent years witnessed a rapid growth of interest of scientific and
engineering communities to thermal properties of materials. Carbon allotropes
and derivatives occupy a unique place in terms of their ability to conduct
heat. The room-temperature thermal conductivity of carbon materials span an
extraordinary large range - of over five orders of magnitude - from the lowest
in amorphous carbons to the highest in graphene and carbon nanotubes. I review
thermal and thermoelectric properties of carbon materials focusing on recent
results for graphene, carbon nanotubes and nanostructured carbon materials with
different degrees of disorder. A special attention is given to the unusual size
dependence of heat conduction in two-dimensional crystals and, specifically, in
graphene. I also describe prospects of applications of graphene and carbon
materials for thermal management of electronics.Comment: Review Paper; 37 manuscript pages; 4 figures and 2 boxe
Exploring the mechanisms of renoprotection against progressive glomerulosclerosis
In this review, I introduce the strategy developed by our laboratory to explore the mechanisms of renoprotection against progressive glomerulosclerosis leading to renal death. First, I describe the experimental rat model in which disturbances of vascular regeneration and glomerular hemodynamics lead to irreversible glomerulosclerosis. Second, I discuss the possible mechanisms determining the progression of glomerulosclerosis and introduce a new imaging system based on intravital confocal laser scanning microscopy. Third, I provide an in-depth review of the regulatory glomerular hemodynamics at the cellular and molecular levels while focusing on the pivotal role of Ca2+-dependent gap junctional intercellular communication in coordinating the behavior of mesangial cells. Last, I show that local delivery of renoprotective agents, in combination with diagnostic imaging of the renal microvasculature, allows the evaluation of the therapeutic effects of angiotensin II receptor and cyclooxygenase activity local blockade on the progression of glomerulosclerosis, which would otherwise lead to renal death
Differences in lipopolysaccharide- and lipoteichoic acid-induced cytokine/chemokine expression
Bacillus anthracis Peptidoglycan Stimulates an Inflammatory Response in Monocytes through the p38 Mitogen-Activated Protein Kinase Pathway
We hypothesized that the peptidoglycan component of B. anthracis may play a critical role in morbidity and mortality associated with inhalation anthrax. To explore this issue, we purified the peptidoglycan component of the bacterial cell wall and studied the response of human peripheral blood cells. The purified B. anthracis peptidoglycan was free of non-covalently bound protein but contained a complex set of amino acids probably arising from the stem peptide. The peptidoglycan contained a polysaccharide that was removed by mild acid treatment, and the biological activity remained with the peptidoglycan and not the polysaccharide. The biological activity of the peptidoglycan was sensitive to lysozyme but not other hydrolytic enzymes, showing that the activity resides in the peptidoglycan component and not bacterial DNA, RNA or protein. B. anthracis peptidoglycan stimulated monocytes to produce primarily TNFα; neutrophils and lymphocytes did not respond. Peptidoglycan stimulated monocyte p38 mitogen-activated protein kinase and p38 activity was required for TNFα production by the cells. We conclude that peptidoglycan in B. anthracis is biologically active, that it stimulates a proinflammatory response in monocytes, and uses the p38 kinase signal transduction pathway to do so. Given the high bacterial burden in pulmonary anthrax, these findings suggest that the inflammatory events associated with peptidoglycan may play an important role in anthrax pathogenesis
Taxation and market power
"We analyze the incidence and welfare effects of unit sales taxes in experimental monopoly and Bertrand markets. We find, in line with economic theory, that firms with no market power are able to shift a high share of a tax burden on to consumers, independent of whether buyers are automated or human players. In monopoly markets, a monopolist bears a large share of the burden of a tax increase. With human buyers, however, this share is smaller than with automated buyers as the presence of human buyers constrains the pricing behavior of a monopolist." (author's abstract)"Dieser Artikel untersucht Inzidenz- und Wohlfahrtseffekte einer Mengensteuer in experimentellen Monopol- und Bertrand-Märkten. Im Einklang mit der ökonomischen Theorie sind Firmen ohne Marktmacht in der Lage, einen großen Anteil der Last einer Steuererhöhung an die Konsumenten weiterzugeben. Dies gilt unabhängig davon, ob die Käufer simuliert sind oder die Kaufentscheidungen durch reale Käufer getroffen werden. In Monopolmärkten trägt der Monopolist einen großen Anteil der Last einer Steuererhöhung. Werden die Kaufentscheidungen durch reale Käufer getroffen, ist dieser Anteil jedoch kleiner als mit simulierten Käufern, da reale Käufer im Experiment das Preissetzungsverhalten des Monopolisten einschränken." (Autorenreferat
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