Helicobacter pylori infection and gastric dysbiosis: Can probiotics administration be useful to treat this condition?

Helicobacter pylori (Hp) is responsible for one of the most common infections in the world. 'e prevalence exceeds 50% of the population in developing countries, and approximately one-third of the adults are colonized in North Europe and North America. It is considered a major pathogenic agent of chronic gastritis, peptic ulcer, atrophic gastritis, gastric cancer, and mucosa-associated lymphoid tissue lymphoma (MALT). Hp colonization modifies the composition of gastric microbiota that could drive the development of gastric disorders. Currently, an emerging problem in Hp treatment is represented by the increasing rate of antimicrobial therapy resistance. In this context, the search for adjuvant agents can be very useful to overcome this issue and probiotics administration can represent a valid option. The aim of this review is to describe the gastric microbiota changes during Hp colonization, the mechanisms of action, and a possible role of probiotics in the treatment of this infection

Improvements on analytic modelling of stellar spots

In this work we present the solution of the stellar spot problem using the Kelvin-Stokes theorem. Our result is applicable for any given location and dimension of the spots on the stellar surface. We present explicitely the result up to the second degree in the limb darkening law. This technique can be used to calculate very efficiently mutual photometric effects produced by eclipsing bodies occulting stellar spots and to construct complex spot shapes.Comment: Resubmitted to MNRAS after accounting for minor comments of second review, 9 pages, 5 figures, software available at http://eduscisoft.com/KSINT

Microwave vs optical crosslink study

The intersatellite links (ISL's) at geostationary orbit is currently a missing link in commercial satellite services. Prior studies have found that potential application of ISL's to domestic, regional, and global satellites will provide more cost-effective services than the non-ISL's systems (i.e., multiple-hop systems). In addition, ISL's can improve and expand the existing satellite services in several aspects. For example, ISL's can conserve the scarce spectrum allocated for fixed satellite services (FSS) by avoiding multiple hopping of the relay stations. ISL's can also conserve prime orbit slot by effectively expanding the geostationary arc. As a result of the coverage extension by using ISL's more users will have direct access to the satellite network, thus providing reduced signal propagation delay and improved signal quality. Given the potential benefits of ISL's system, it is of interest to determine the appropriate implementations for some potential ISL architectures. Summary of the selected ISL network architecture as supplied by NASA are listed. The projected high data rate requirements (greater than 400 Mbps) suggest that high frequency RF or optical implementations are natural approaches. Both RF and optical systems have their own merits and weaknesses which make the choice between them dependent on the specific application. Due to its relatively mature technology base, the implementation risk associated with RF (at least 32 GHz) is lower than that of the optical ISL's. However, the relatively large antenna size required by RF ISL's payload may cause real-estate problems on the host spacecraft. In addition, because of the frequency sharing (for duplex multiple channels communications) within the limited bandwidth allocated, RF ISL's are more susceptible to inter-system and inter-channel interferences. On the other hand, optical ISL's can offer interference-free transmission and compact sized payload. However, the extremely narrow beam widths (on the order of 10 micro-rad) associated with optical ISL's impose very stringent pointing, acquisition, and tracking requirements on the system. Even if the RF and optical systems are considered separately, questions still remain as to selection of RF frequency, direct versus coherent optical detection, etc. in implementing an ISL for a particular network architecture. These and other issues are studied

Hyperentangled mixed phased Dicke states: optical design and detection

We present an experimental method to produce 4-qubit phased Dicke states, based on a source of 2-photon hyperentangled states. By introducing quantum noise in the multipartite system in a controlled way, we have tested the robustness of these states. To this purpose the entanglement of the resulting multipartite entangled mixed states has been verified by using a new kind of structural witness.Comment: 6 pages, 3 figure, supplementary information include

On the Numerical Accuracy of Spreadsheets

This paper discusses the numerical precision of five spreadsheets (Calc, Excel, Gnumeric, NeoOffice and Oleo) running on two hardware platforms (i386 and amd64) and on three operating systems (Windows Vista, Ubuntu Intrepid and Mac OS Leopard). The methodology consists of checking the number of correct significant digits returned by each spreadsheet when computing the sample mean, standard deviation, first-order autocorrelation, F statistic in ANOVA tests, linear and nonlinear regression and distribution functions. A discussion about the algorithms for pseudorandom number generation provided by these platforms is also conducted. We conclude that there is no safe choice among the spreadsheets here assessed: they all fail in nonlinear regression and they are not suited for Monte Carlo experiments.

SOPHIE velocimetry of Kepler transit candidates IX. KOI-415 b: a long-period, eccentric transiting brown dwarf to an evolved Sun

We report the discovery of a long-period brown-dwarf transiting companion of the solar-type star KOI-415. The transits were detected by the Kepler space telescope. We conducted Doppler measurements using the SOPHIE spectrograph at the Observatoire de Haute-Provence. The photometric and spectroscopic signals allow us to characterize a 62.14+-2.69 Mjup, brown-dwarf companion of an evolved 0.94+-0.06 Msun star in a highly eccentric orbit of P = 166.78805+-0.00022 days and e = 0.698+-0.002. The radius of KOI-415 b is 0.79 (-0.07,+0.12) Rjup, a value that is compatible with theoretical predictions for a 10 Gyr, low-metallicity and non-irradiated object.Comment: accepted in A&A Letter