Ba & Eu Abundances in M15 giant stars

To investigate the Ba and Eu abundances for a sample of 63 giant stars in the globular cluster M15. This is the largest sample of M15 giants stars for which Ba abundances have been determined and, due to the target selection of the original research programme, the Ba abundances are complete along the red giant branch. Stellar parameters were taken from the previous key study and a microturbulence-surface gravity relation was determined for precise measurement of the Ba line at 6496.898 Angstroms, which has a high sensitivity to microturbulence. Element abundances for Ba, La, Eu, Ca, Ni and Fe were calculated using spectrum synthesis and equivalent widths techniques. A bimodal distribution in Ba, Eu and La abundances was found within the sample. The low Ba,Eu,La mode had mean abundances of =-2.41+/-0.16, =-1.80+/-0.08 and =-2.19+/-0.13 while the high Ba,Eu,La mode had mean abundances of =-2.00+/-0.16, =-1.65+/-0.13 and =-1.95+/-0.11. Both modes are indicative of a pollution scenario dominated by the r-process, hence contributions from explosive nucleosynthesis of massive stars. There may be evidence of further enhancement by another heavy element process and of potential anticorrelations in Na-O for both modes indicating a complex formation and evolution history for M15.Comment: 20 pages, 15 figure

Differential chemical abundance analysis of a 47 Tuc AGB star with respect to Arcturus

This study resolves a discrepancy in the abundance of Zr in the 47 Tucanae asymptotic giant branch star Lee 2525. This star was observed using the echelle spectrograph on the 2.3 m telescope at Siding Spring Observatory. The analysis was undertaken by calibrating Lee 2525 with respect to the standard giant star Arcturus. This work emphasises the importance of using a standard star with stellar parameters comparable to the star under analysis rather than a calibration with respect to the Sun (Koch & McWilliam 2008). Systematic errors in the analysis process are then minimised due to the similarity in atmospheric structure between the standard and programme stars. The abundances derived for Lee 2525 were found to be in general agreement with the Brown & Wallerstein (1992) values except for Zr. In this study Zr has a similar enhancement ([Zr/Fe] = +0.51 dex) to another light s-process element, Y ([Y/Fe] = +0.53 dex), which reflects current theory regarding the enrichment of s-process elements by nuclear processes within AGB stars (Busso et al. 2001). This is contrary to the results of Brown & Wallerstein (1992) where Zr was under-abundant ([Zr/Fe] = +0.51 dex) and Y was over-abundant ([Y/Fe] = +0.50 dex) with respect to Fe.Comment: 11 pages, 5 figures Accepted for publication in MNRA

The Metabolism and Transplacental Transfer of Oseltamivir in the Ex Vivo Human Model

Oseltamivir phosphate is extensively metabolized in the ex vivo human placenta model, and the transplacental passage of the metabolite oseltamivir carboxylate is incomplete. Objective. To evaluate the metabolism and transplacental transfer of oseltamivir (Tamiflu) in the ex vivo human placental model. Study Design. Perfusion studies were performed in six placentas from term, uncomplicated deliveries. Concentrations of oseltamivir phosphate (OP) that were 5-6 fold, 20–30 fold, and 600–800 fold above the therapeutic peak were tested, as neither OP nor its active metabolite, oseltamivir carboxylate (OC), could be detected at near-therapeutic concentrations. The transplacental transfer and accumulation of OC were assessed using the 14C antipyrine reference method. Results. OP was extensively metabolized to OC. In the 4 placentas with the highest concentration of OP, OC had a mean clearance index of 0.13 ± 0.08, suggesting that transplacental passage occurs at a relatively low rate. Measurable fetal accumulation occurred in the two placentas with the highest initial concentrations. Conclusions. Oseltamivir phosphate was extensively metabolized in the ex vivo model. Transplacental transfer of the metabolite was incomplete and accumulation was minimal

Prerequisites for Successful Fiscal Reform: Some Preliminary Results

Journal of Public Budgeting, Accounting and Financial Management, Winter 1998.Refereed Journal ArticleThis paper examines whether any relationship exists between success or failure of policy reform on the one hand, and various political/economic conditions in place at the time of reform on the other. Nineteen countries were scored using three financial variables to measure the degree of success or failure of the reform. The independent variables were country scores for ten different economic and political conditions. The independent variables were used to try and predict a priori which of the nineteen countries would succeed and which would fail. Eighteen of the nineteen countries were correctly placed into their respective success group. However only three of the ten conditions appeared important in predicting success: a visionary leader, a crisis, and a comprehensive program. Other writers have suggested different sets of predicting variables

Recent progress on the accurate determination of the equation of state of neutron and nuclear matter

The problem of accurately determining the equation of state of nuclear and neutron matter at density near and beyond saturation is still an open challenge. In this paper we will review the most recent progress made by means of Quantum Monte Carlo calculations, which are at present the only ab-inito method capable to treat a sufficiently large number of particles to give meaningful estimates depending only on the choice of the nucleon-nucleon interaction. In particular, we will discuss the introduction of density-dependent interactions, the study of the temperature dependence of the equation of state, and the possibility of accurately studying the effect of the onset of hyperons by developing an accurate hyperon-nucleon and hyperon-nucleon-nucleon interaction.Comment: 3 figures, 1 table, to appear in the Proceedings of "XIII Convegno di Cortona su Problemi di Fisica Nucleare Teorica", Cortona (Italy), April 6-8, 201

s- and r-process element abundances in the CMD of 47 Tucanae using the Robert Stobie Spectrograph on SALT

A recent study by Wylie et al 2006 has revealed that s-process element abundances are enhanced relative to iron in both red giant branch and asymptotic giant branch stars of 47 Tucanae. A more detailed investigation into s-process element abundances throughout the colour-magnitude diagram of 47 Tucanae is vital in order to determine whether the observed enhancements are intrinsic to the cluster. This paper explores this possibility through observational and theoretical means. The visibility of s- and r-process element lines in synthetic spectra of giant and dwarf stars throughout the colour magnitude diagram of 47 Tucanae has been explored. It was determined that a resolving power of 10 000 was sufficient to observe s-process element abundance variations in globular cluster giant branch stars. These synthetic results were compared with the spectra of eleven 47 Tucanae giant branch stars observed during the performance verification of the Robert Stobie Spectrograph on the Southern African Large Telescope. Three s-process elements, Zr, Ba, Nd, and one r-process element, Eu, were investigated. No abundance variations were found such that [X/Fe] = 0.0 +/- 0.5 dex. It was concluded that this resolving power, R ~ 5000, was not sufficient to obtain exact abundances but upper limits on the s-process element abundances could be determined.Comment: 7 pages, 11 figure

The Gaia-ESO Survey: N-body modelling of the Gamma Velorum cluster

The Gaia-ESO Survey has recently unveiled the complex kinematic signature of the Gamma Velorum cluster: this cluster is composed of two kinematically distinct populations (hereafter, population A and B), showing two different velocity dispersions and a relative ~2 km s^-1 radial velocity (RV) shift. In this paper, we propose that the two populations of the Gamma Velorum cluster originate from two different sub-clusters, born from the same parent molecular cloud. We investigate this possibility by means of direct-summation N-body simulations. Our scenario is able to reproduce not only the RV shift and the different velocity dispersions, but also the different centroid (~0.5 pc), the different spatial concentration and the different line-of-sight distance (~5 pc) of the two populations. The observed 1-2 Myr age difference between the two populations is also naturally explained by our scenario, in which the two sub-clusters formed in two slightly different star formation episodes. Our simulations suggest that population B is strongly supervirial, while population A is close to virial equilibrium. We discuss the implications of our models for the formation of young star clusters and OB associations in the Milky Way.Comment: 12 pages, 7 figures, 2 tables, Astronomy and Astrophysics, in pres

Renal and Segmental Artery Hemodynamic Response to Mild Hypercapnia

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The AMBRE project: chemical evolution models for the Milky Way thick and thin discs

We study the chemical evolution of the thick and thin discs of the Galaxy by comparing detailed chemical evolution models with recent data from the Archéologie avec Matisse Basée sur les aRchives de l'ESO project. The data suggest that the stars in the thick and thin discs form two distinct sequences with the thick disc stars showing higher [α/Fe] ratios. We adopt two different approaches to model the evolution of thick and thin discs. In particular, we adopt (i) a two-infall approach where the thick disc forms fast and before the thin disc and by means of a fast gas accretion episode, whereas the thin disc forms by means of a second accretion episode on a longer time-scale; (ii) a parallel approach, where the two discs form in parallel but at different rates. By comparing our model results with the observed [Mg/Fe] versus [Fe/H] and the metallicity distribution functions in the two Galactic components, we conclude that the parallel approach can account for a group of α-enhanced metal-rich stars present in the data, whereas the two-infall approach cannot explain these stars unless they are the result of stellar migration. In both approaches, the thick disc has formed on a time-scale of accretion of 0.1 Gyr, whereas the thin disc formed on a time-scale of 7 Gyr in the solar region. In the two-infall approach, a gap in star formation between the thick and thin disc formation of several hundreds of Myr should be present, at variance with the parallel approach where no gap is present

The Gaia-ESO Survey: Tracing interstellar extinction

Large spectroscopic surveys have enabled in the recent years the computation of three-dimensional interstellar extinction maps thanks to accurate stellar atmospheric parameters and line-of-sight distances. Such maps are complementary to 3D maps extracted from photometry, allowing a more thorough study of the dust properties. Our goal is to use the high-resolution spectroscopic survey Gaia-ESO in order to obtain with a good distance resolution the interstellar extinction and its dependency as a function of the environment and the Galactocentric position. We use the stellar atmospheric parameters of more than 5000 stars, obtained from the Gaia-ESO survey second internal data release, and combine them with optical (SDSS) and near-infrared (VISTA) photometry as well as different sets of theoretical stellar isochrones, in order to calculate line-of-sight extinction and distances. The extinction coefficients are then compared with the literature to discuss their dependancy on the stellar parameters and position in the Galaxy. Within the errors of our method, our work does not show that there is any dependence of the interstellar extinction coefficient on the atmospheric parameters of the stars. We do not find any evidence of the variation of E(J-H)/E(J-K) with the angle from the Galactic centre nor with Galactocentric distance. This suggests that we are dealing with a uniform extinction law in the SDSS ugriz bands and the near-IR JHKs bands. Therefore, extinction maps using mean colour-excesses and assuming a constant extinction coefficient can be used without introducing any systematic errors.Comment: 13 pages, 14 figures, 1 Appendix accepted for publication in Astronomy&Astrophysic