42 research outputs found

    Effect of Cubic Temperature Profiles on Ferro Convection in a Brinkman Porous Medium

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    The effect of cubic temperature profiles on the onset ferroconvection in a Brinkman porous medium in presence of a uniform vertical magnetic field is studied. The lower and upper boundaries are taken to be rigid-isothermal and ferromagnetic. The Rayleigh-Ritz method with Chebyshev polynomials of the second kind as trial functions is employed to extract the critical stability parameters numerically. The results indicate that the stability of ferroconvection is significantly affected by cubic temperature profiles and the mechanism for suppressing or augmenting the same is discussed in detail. It is observed that the effect of Darcy number magnetic number and nonlinearity of the fluid magnetization parameter is to hasten, while an increase in the ratio of viscosity parameter and Biot number is to delay the onset of ferroconvection in a Brinkman porous medium. Further, increase in and decrease in is to decrease the size of the convection cells

    Potency analysis of cellular therapies: the emerging role of molecular assays

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    Potency testing is an important part of the evaluation of cellular therapy products. Potency assays are quantitative measures of a product-specific biological activity that is linked to a relevant biological property and, ideally, a product's in vivo mechanism of action. Both in vivo and in vitro assays can be used for potency testing. Since there is often a limited period of time between the completion of production and the release from the laboratory for administration to the patient, in vitro assays such are flow cytometry, ELISA, and cytotoxicity are typically used. Better potency assays are needed to assess the complex and multiple functions of cellular therapy products, some of which are not well understood. Gene expression profiling using microarray technology has been widely and effectively used to assess changes of cells in response to stimuli and to classify cancers. Preliminary studies have shown that the expression of noncoding microRNA which play an important role in cellular development, differentiation, metabolism and signal transduction can distinguish different types of stem cells and leukocytes. Both gene and microRNA expression profiling have the potential to be important tools for testing the potency of cellular therapies. Potency testing, the complexities associated with potency testing of cellular therapies, and the potential role of gene and microRNA expression microarrays in potency testing of cellular therapies is discussed

    Effect of non-uniform concentration distribution on double diffusive convection in magnetic fluid

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    427-435<span style="font-size:11.0pt;line-height:115%; font-family:" calibri","sans-serif";mso-ascii-theme-font:minor-latin;mso-fareast-font-family:="" "times="" new="" roman";mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:="" minor-latin;mso-bidi-font-family:arial;mso-ansi-language:en-us;mso-fareast-language:="" en-us;mso-bidi-language:ar-sa"="">The effect of non-uniform concentration distribution on double diffusive convection in a Boussinesq magnetic fluid layer confined between two rigid boundaries is studied analytically using the Galerkin method. The condition for direct and oscillatory modes for different non-linear basic concentration distributions is establislied. It is shown that different non-uniform concentration gradients and diffusivity ratio significantly influence the stability of the system when convection is induced by buoyancy force and/or magnetization.</span

    Effect of basic temperature gradients on Marangoni convection in ferromagnetic fluids

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    95-106<span style="font-size: 15.5pt;mso-bidi-font-size:8.5pt;font-family:" times="" new="" roman","serif""="">The effect of different basic temperature gradients on the onset of Marangoni ferroconvection is studied. The resulting eigenvalue problem is solved by Galerkin technique for the lower boundary rigid and either conducting or adiabatic and the upper boundary at which the surface tension acts is free adiabatic. The results indicate that the stability of Marangoni ferroconvection is significantly affected by basic temperature gradients and the mechanism for suppressing or augmenting the same is discussed in detail. It is found that, the results obtained under the limiting conditions compare well with the existing ones. </span

    Effect of non-uniform concentration distribution on double diffusive convection in magnetic fluids

    No full text
    The effect of non-uniform concentration distribution on double diffusive convection in a Boussinesq magnetic fluid layer confined between two rigid boundaries is studied analytically using the Galerkin method. The condition for direct and oscillatory modes for different non-linear basic concentration distributions is established. Different non-uniform concentration gradients and diffusivity ratio significantly influence the stability of the system when convection is induced by buoyancy force and/or magnetization

    Effect of basic temperature gradients on Marangoni convection in ferromagnetic fluids

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    The effect of different basic temperature gradients on the onset of Marangoni ferroconvection is studied. The resulting eigenvalue problem is solved by Galerkin technique for the lower boundary rigid and either conducting or adiabatic and the upper boundary at which the surface tension acts is free adiabatic. The results indicate that the stability of Marangoni ferroconvection is significantly affected by basic temperature gradients and the mechanism for suppressing or augmenting the same is discussed in detail. It is found that, the results obtained under the limiting conditions compare well with the existing ones
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